Patents by Inventor Robert E. Handschumacher

Robert E. Handschumacher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immobilized cyclophilin and methods of using such
    Patent number: 5047512
    Abstract: Homogeneous cyclophilin, a soluble binding protein, having a specific binding activity of above 50 ug cyclosporin A per mg protein and a molecular weight of about 17,600 daltons, reversibly binds immunosuppressants or antibodies thereto such as cyclosporin or anti-cyclophilin. It is isolated from the cytosol of several different mammalian tissues and can be used in various diagnostic and purifications procedures.
    Type: Grant
    Filed: June 23, 1987
    Date of Patent: September 10, 1991
    Inventors: Robert E. Handschumacher, Matthew W. Harding, David W. Speicher
  • Cyclophilin
    Patent number: 4722999
    Abstract: Homogeneous cyclophilin, a soluble binding protein, having a specific binding activity of above 50 ug cyclosporin A per mg protein and a molecular weight of about 17,600 daltons, reversibly binds immunosuppressants or antibodies thereto such as cyclosporin or anti-cyclophilin. It is isolated from thecytosol of several different mammalian tissues and can be used in various diagnostic and purifications procedures.
    Type: Grant
    Filed: May 3, 1985
    Date of Patent: February 2, 1988
    Assignee: Yale University
    Inventors: Robert E. Handschumacher, Matthew W. Harding, David W. Speicher