Abstract: The embodiments disclosed herein relate to diagnostic products, and more particularly to lateral flow devices for detecting, for example, infectious diseases, molecules derived from infectious agents, and toxic substances. In an embodiment, a lateral flow device includes a top portion including a self-sealing test sample port and a self-sealing test reagent port; a bottom portion including a channel sufficiently designed to hold a lateral flow test strip; a test sample well sufficiently designed to accept and filter components of a test sample; a test reagent well sufficiently designed to accept components of a test reagent; and a tilting frame sufficiently designed to press the test reagent well against the lateral flow test strip while simultaneously lifting the test sample well from the lateral flow test strip.

Abstract: A method is disclosed treating a tumor in a host by administering a nonemulsified ultrapurified polymerized hemoglobin solution to the host and also administering a chemotherapeutic agent to the host. In a particularly preferred embodiment, the hemoglobin is bovine hemoglobin.

Abstract: Male animals may be chemically castrated by injecting both testes and/or both spermatic cords with a castratingly effective amount of a protease enzyme such as a chymopapain-rich enzyme preparation.

Abstract: An optical density technique for measuring protein concentration generally, or for measuring minute traces of endotoxin in an unknown material by the clotting of Limulus lysate protein. After the clotting step, the clotted protein is separated and digested in from 0.1 to 0.4N strong alkali such as sodium hydroxide and then photometrically analyzed, for example with the Lowry test. Greatly improved stability of a quantitative endopoint is achieved under this circumstance.

Abstract: A family of catalysts is disclosed for providing improved capacity for Limulus lysate solution to precipitate in the presence of extremely low concentrations of endotoxin. The catalyst family includes imidazole, manganese ions, Cleland's reagent, magnesium ions, strontium ions, barium ions, cysteine, lithium ions, and various combinations of the above materials. Solutions of the above catalysts may be used to advantage to reconstitute lyophilized Limulus lysate.