Abstract: A device, system, and method for maintaining temperature control of a distribution item, or of the contents of a distribution item, as the distribution item moves through the distribution network. A container housing an item can include a cooling unit, a heating unit, or both, and control circuitry including a temperature sensor. The control circuitry activates the cooling unit or heating unit as required to maintain the item at a desired temperature or within a desired temperature range.

Abstract: A system includes a mandrel contoured to define a tapering tubular shape of a workpiece cured on the mandrel and a demolding tool. The demolding tool is configured to remove the workpiece from the mandrel after the workpiece is cured on the mandrel and cut longitudinally. The demolding tool is configured to remove the workpiece from the mandrel by deforming a first end of the workpiece to at least partially disengage the first end of the workpiece from a first end of the mandrel, and subsequently, deforming a second end of the workpiece to at least partially disengage the second end of the workpiece from a second end of the mandrel. The first end of the workpiece may have a first cross-sectional area that is smaller than a second cross-sectional area of the second end of the workpiece.

Abstract: Disclosed are various embodiments for facilitating the cancellation or reversion of unauthorized operations. An operation initiated to be executed with respect to a user account is received from a computing device that has been authenticated. A notification of the operation is sent through at least one communication channel in response to receiving the operation. The notification facilitates a reply that causes the operation to be cancelled when the reply is sent within a first time period and causes the operation to be reverted when the reply is sent within a second time period after an expiration of the first time period.

Abstract: A security system is provided. The security system includes a control panel located within a secured space, a plurality of sensors coupled to the control panel that detect security events within the secured space, a user interface within the secured area coupled to the control panel, a camera located in the user interface that collects video images in the secured space surrounding the user interface upon activation of one of the plurality of sensors, a sound transducer located in the user interface, a programmed processor within one of the user interface and the control panel that supports VoIP calls between a called or calling party and the user interface and a control button on the user interface that activates a VoIP connection with a called or calling party through the user interface and control panel.

Abstract: Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.

Abstract: A system includes a mandrel contoured to define a tapering tubular shape of a workpiece cured on the mandrel and a demolding tool. The demolding tool is configured to remove the workpiece from the mandrel after the workpiece is cured on the mandrel and cut longitudinally. The demolding tool is configured to remove the workpiece from the mandrel by deforming a first end of the workpiece to at least partially disengage the first end of the workpiece from a first end of the mandrel, and subsequently, deforming a second end of the workpiece to at least partially disengage the second end of the workpiece from a second end of the mandrel. The first end of the workpiece may have a first cross-sectional area that is smaller than a second cross-sectional area of the second end of the workpiece.

Abstract: Disclosed herein are crystalline forms of ((2-Ethylbutanoyl)oxy)methyl (R)-2-hydroxy-3-propionamido-3,4-dihydro-2H-benzo[e][1,2]oxaborinine-8-carboxylate. Also disclosed herein are methods of treating a bacterial with a crystalline form of ((2-Ethylbutanoyl)oxy)methyl (R)-2-hydroxy-3-propionamido-3,4-dihydro-2H-benzo[e][1,2]oxaborinine-8-carboxylate.

Abstract: Described herein are certain boron-containing compounds, compositions, preparations and their use as modulators of the transpeptidase function of bacterial penicillin-binding proteins and as antibacterial agents. In some embodiments, the compounds described herein inhibit penicillin-binding proteins. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.

Abstract: The present invention relates to pharmaceutical compositions containing boron-containing compounds and their use as inhibitors of beta-lactamase enzymes and as antibacterial agents in combination with a beta-lactam antibiotic.

Abstract: Described herein are certain boron-containing compounds, compositions, preparations and their use as modulators of the transpeptidase function of bacterial penicillin-binding proteins and as antibacterial agents. In some embodiments, the compounds described herein inhibit penicillin-binding proteins. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.

Abstract: Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.

Abstract: A power-take off (PTO) system for a vehicle having a powertrain comprising an engine and a hybrid electric transmission includes a PTO device configured to provide power to an accessory load of the vehicle, a housing for a gear clutch of the transmission, the housing being formed of steel, needle bearings for the gear clutch, and a gear defined by or attached to an outer surface of the housing, wherein at least one electric motor of the transmission is configured to drive the PTO device via the gear clutch and the gear while the engine is disconnected from the transmission or is shut off.

Abstract: Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.

Abstract: Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.

Abstract: Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.

Abstract: Described herein are certain boron-containing compounds, compositions, preparations and their use as modulators of the transpeptidase function of bacterial penicillin-binding proteins and as antibacterial agents. In some embodiments, the compounds described herein inhibit penicillin-binding proteins. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.

Abstract: The disclosed embodiments provide a system that manages access to a computer-based resource. During operation, the system obtains a request for the computer-based resource, wherein the request identifies a user seeking access to the computer-based resource. Next, the system obtains a set of security levels for a set of identity-proofing techniques, wherein the set of security levels is based on a first set of success rates of the identity-proofing techniques in preventing fraudulent access to computer-based resources. The system then calculates an identity assurance level for the user based on the set of security levels and a second set of success rates of the user in completing one or more of the identity-proofing techniques. Upon determining that the identity assurance level of the user meets a minimum identity assurance level for accessing the computer-based resource, the system enables access to the computer-based resource in a response to the request.

Abstract: Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.

Abstract: Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.

Abstract: Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.