Patents by Inventor Robert E. McDevitt

Robert E. McDevitt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6451827
    Abstract: This invention provides compounds of Formula I having the structure wherein: B, C, D, and R1 are as defined hereinbefore in the specification, or a pharmaceutically acceptable salt thereof, which are useful in treating metabolic disorders related to insulin resistance or hyperglycemia.
    Type: Grant
    Filed: January 26, 2001
    Date of Patent: September 17, 2002
    Assignee: Wyeth
    Inventors: John A. Butera, Craig E. Caufield, Russell F. Graceffa, Alexander Greenfield, Eric G. Gundersen, Lisa Marie Havran, Alan H. Katz, Joseph R. Lennox, Scott C. Mayer, Robert E. McDevitt
  • Patent number: 6391897
    Abstract: This invention provides substituted compounds of the general formulae: wherein B and E are C or N; D, G and W are O, S, or N; or salt forms thereof, and methods and pharmaceutical compositions for their use in treating disorders related to insulin resistance or hyperglycemia.
    Type: Grant
    Filed: March 2, 2001
    Date of Patent: May 21, 2002
    Assignee: American Home Products Corporation
    Inventors: Michael S. Malamas, Robert E. McDevitt, Folake O. Adebayo
  • Patent number: 6369072
    Abstract: This invention provides substituted compounds of the general formulae: wherein B and E are C or N; D, G and W are O, S, or N; or salt forms thereof, and methods and pharmaceutical compositions for their use in treating disorders related to insulin resistance or hyperglycemia.
    Type: Grant
    Filed: March 2, 2001
    Date of Patent: April 9, 2002
    Assignee: American Home Products Corporation
    Inventors: Michael S. Malamas, Robert E. McDevitt, Folake O. Adebayo
  • Patent number: 6362170
    Abstract: This invention provides smooth muscle cell proliferation inhibitors of formula I having the structure wherein Y is C or N; where n is 0-3; X is R1, and R2 are each independently, hydrogen, alkyl of 1 to 6 carbon atoms, halo, acetyl, phenyl, CF3, CN, OH, NO2, NH2, alkoxy of 1 to 6 carbon atoms, or alkoxynitrile of 1 to 6 carbon atoms; R3 is hydrogen, acylamide of 2 to 6 carbon atoms or alkoxy of 1 to 6 carbon atoms; R4, R5, R6, R7, and R8 are each, independently, acyl of 1 to 6 carbon atoms, benzyl substituted with R1, and R2; or benzoyl substituted with R1 and R2; R9 and R10 are each, independently, acyl of 1 to 6 carbon atoms, or the R9 and R10 groups on the 4′ and 6′ positions of the maltose may be taken together to form a cyclic acetal which may be substituted with alkyl of 1 to 6 carbon atoms, two alkyl groups each having 1 to 6 carbon atoms, pyridine substituted with R1, phenyl substituted with R1, benzyl substituted with R1, 2-phenylethyl substituted
    Type: Grant
    Filed: November 22, 1999
    Date of Patent: March 26, 2002
    Assignee: American Home Products Corporation
    Inventors: Robert E. McDevitt, Folake O. Adebayo
  • Publication number: 20020035272
    Abstract: This invention provides compounds of Formula I having the structure 1
    Type: Application
    Filed: April 23, 2001
    Publication date: March 21, 2002
    Applicant: American Home Products Corporation
    Inventors: Paul J. Dollings, Robert E. McDevitt, Folake O. Adebayo
  • Patent number: 6340670
    Abstract: This invention provides smooth muscle cell proliferation inhibitors of formula I having the structure with the variables defined herein.
    Type: Grant
    Filed: November 22, 1999
    Date of Patent: January 22, 2002
    Assignee: American Home Products Corporation
    Inventors: Scott C. Mayer, Paul J. Dollings, Robert E. McDevitt
  • Patent number: 6339064
    Abstract: This invention provides smooth muscle cell proliferation inhibitors of formula I having the structure wherein Y is C or N; where n is 0-3; X is R1, and R2 are independently, hydrogen, alkyl of 1 to 6 carbon atoms, or halo, acetyl, phenyl, CF3, CN, OH, NO2, NH2, alkoxy of 1 to 6 carbon atoms, or cyanoalkoxy of 2 to 7 carbon atoms; R3 is hydrogen, acylamide of 2 to 6 carbon atoms or alkoxy of 1 to 6 carbon atoms; R4, R5, R6, R7, and R8 are each, independently, acyl of 1 to 6 carbon atoms, benzyl substituted with R1, and R2; or benzoyl substituted with R1 and R2; R9 and R10 are each, independently, acyl of 1 to 6 carbon atoms, or the R9 and R10 groups on the 4′ and 6′ positions of the maltose may be taken together to form a cyclic acetal which may be substituted with alkyl of 1 to 6 carbon atoms, two alkyl groups each having 1 to 6 carbon atoms, pyridine substituted with R1, phenyl substituted with R1, benzyl substituted with R1, 2-phenylethyl substituted wit
    Type: Grant
    Filed: November 22, 1999
    Date of Patent: January 15, 2002
    Assignee: American Home Products Corporation
    Inventors: Robert E. McDevitt, Folake O. Adebayo
  • Publication number: 20010018525
    Abstract: This invention provides compounds of Formula I having the structure 1
    Type: Application
    Filed: January 26, 2001
    Publication date: August 30, 2001
    Inventors: John A. Butera, Craig E. Caufield, Russell F. Graceffa, Alexander Greenfield, Eric G. Gundersen, Lisa M. Havran, Alan H. Katz, Joseph R. Lennox, Scott C. Mayer, Robert E. McDevitt
  • Patent number: 6248764
    Abstract: This invention provides compounds of Formula I having the structure or a pharmaceutically acceptable salt thereof, which are useful in treating metabolic disorders related to insulin resistance or hyperglycemia.
    Type: Grant
    Filed: May 4, 2000
    Date of Patent: June 19, 2001
    Assignee: American Home Products Corporation
    Inventors: Paul J. Dollings, Robert E. McDevitt, Folake O. Adebayo
  • Patent number: 6232322
    Abstract: This invention provides compounds of Formula I having the structure wherein A, R3, R4, and R5 are as defined hereinbefore in the specification, or a pharmaceutically acceptable salt thereof, which are useful in treating metabolic disorders related to insulin resistance or hyperglycemia.
    Type: Grant
    Filed: May 10, 1999
    Date of Patent: May 15, 2001
    Assignee: American Home Products Corporation
    Inventors: Michael S. Malamas, Robert E. McDevitt, Folake O. Adebayo
  • Patent number: 6214877
    Abstract: This invention provides compounds of Formula I having the structure wherein: B, C, D, and R1 are as defined hereinbefore in the specification, or a pharmaceutically acceptable salt thereof, which are useful in treating metabolic disorders related to insulin resistance or hyperglycemia.
    Type: Grant
    Filed: May 10, 1999
    Date of Patent: April 10, 2001
    Inventors: John A. Butera, Craig E. Caufield, Russell F. Graceffa, Alexander Greenfield, Eric G. Gundersen, Lisa Marie Havran, Alan H. Katz, Joseph R. Lennox, Scott C. Mayer, Robert E. McDevitt
  • Patent number: 6103708
    Abstract: This invention provides compounds of Formula I having the structure: ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, W, X, Y, and Z are as defined in the specification, or a pharmaceutically acceptable salt thereof, which are useful in treating metabolic disorders related to insulin resistance or hyperglycemia.
    Type: Grant
    Filed: May 10, 1999
    Date of Patent: August 15, 2000
    Assignee: American Home Products Corporation
    Inventors: Paul J. Dollings, Robert E. McDevitt, Folake O. Adebayo