Patents by Inventor Robert E. Ormond

Robert E. Ormond has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Strain of Streptomyces for producing antiparasitic compounds
    Patent number: 4429042
    Abstract: Novel compounds are produced by the fermentation of a nutrient medium with the previously undescribed microorganism Streptomyces avermitilis. They may be isolated by solvent extraction and chromatographic fractionation techniques. The compounds, which are described generically as C-076 have significant parasiticidal activity. The compounds may be included in compositions for the oral or parenteral administration to animals for the prevention and cure of parasitic infections.
    Type: Grant
    Filed: December 30, 1981
    Date of Patent: January 31, 1984
    Assignee: Merck & Co., Inc.
    Inventors: George Albers-Schonberg, Hyman Wallick, Robert E. Ormond, Thomas W. Miller, Richard W. Burg
  • 22-Hydroxy derivatives of C-076 compounds, pharmaceutical compositions and method of use
    Patent number: 4412991
    Abstract: There is disclosed novel derivatives of C-076 compounds wherein the 22-position, normally substituted, is substituted with a hydroxy group. The compounds are isolated from the C-076 fermentation broth of Streptomyces avermitilis. The compounds have potent anthelmintic, insecticidal, and acaricidal activity and compositions for that use are also disclosed.
    Type: Grant
    Filed: August 28, 1981
    Date of Patent: November 1, 1983
    Assignee: Merck & Co., Inc.
    Inventor: Robert E. Ormond
  • Novel substances and process for their production
    Patent number: 4310519
    Abstract: Novel compounds are produced by the fermentation of a nutrient medium with the previously undescribed microorganism Streptomyces avermitilis. They may be isolated by solvent extraction and chromatographic fractionation techniques. The compounds, which are described generically as C-076 have significant parasiticidal activity. The compounds may be included in compositions for the oral or parenteral administration to animals for the treatment of parasitic infections.
    Type: Grant
    Filed: September 8, 1978
    Date of Patent: January 12, 1982
    Assignee: Merck & Co., Inc.
    Inventors: George Albers-Schonberg, Hyman Wallick, Robert E. Ormond, Thomas W. Miller, Richard W. Burg
  • Method for the separation of antibiotic macrolides
    Patent number: 4160084
    Abstract: This case relates to a novel process which aids in the isolation and purification of novel compounds which are produced by the microorganism, Streptomyces avermitilis. The process described utilizes a column containing a hydroxyalkylated dextran gel as a step in the separation of the desired compounds. The compounds which are isolated and purified are described generically as C-076 and have significant parasiticidal activity.
    Type: Grant
    Filed: October 11, 1977
    Date of Patent: July 3, 1979
    Assignee: Merck & Co., Inc.
    Inventors: Thomas W. Miller, Kenneth E. Wilson, Robert E. Ormond