Abstract: Disclosed herein are diagnostic assays using surface enhanced Raman spectroscopy (SERS)-active particles, including liquid-based assays; magnetic capture assays; microparticle-nanoparticle satellite structures for signal amplification in an assay; composite SERS-active particles useful for enhanced detection of targets; and sample tubes and processes for using the same.

Abstract: Disclosed herein are diagnostic assays using surface enhanced Raman spectroscopy (SERS)-active particles, including liquid-based assays; magnetic capture assays; microparticle-nanoparticle satellite structures for signal amplification in an assay; composite SERS-active particles useful for enhanced detection of targets; and sample tubes and processes for using the same.

Abstract: Disclosed herein are diagnostic assays using surface enhanced Raman spectroscopy (SERS)-active particles, including liquid-based assays; magnetic capture assays; microparticle-nanoparticle satellite structures for signal amplification in an assay; composite SERS-active particles useful for enhanced detection of targets; and sample tubes and processes for using the same.

Abstract: The present invention is a foldable device for retrieving golf, tennis, or other balls. The invention comprises an elongated shaft having handles at one end and a pair of elongated arm members hinged to the shaft at an opposite end. When fully deployed, the arm members form a V-shaped collection member adapted to be moved along the surface of a putting green or tennis court to gather scattered balls within a first region of the collection member and then collect the gathered balls within a second region of the collection member for eventual lifting and transport.

Abstract: Disclosed herein are diagnostic assays using surface enhanced Raman spectroscopy (SERS)-active particles, including liquid-based assays; magnetic capture assays; microparticle-nanoparticle satellite structures for signal amplification in an assay; composite SERS-active particles useful for enhanced detection of targets; and sample tubes and processes for using the same.

Abstract: The present invention is a foldable device for retrieving golf, tennis, or other balls. The invention comprises an elongated shaft having handles at one end and a pair of elongated arm members hinged to the shaft at an opposite end. When fully deployed, the arm members form a V-shaped collection member adapted to be moved along the surface of a putting green or tennis court to gather scattered balls within a first region of the collection member and then collect the gathered balls within a second region of the collection member for eventual lifting and transport.

Abstract: Strand Displacement Amplification has been adapted to reverse transcription amplification of RNA targets. The method of the invention is referred to as reverse transcription SDA (rtSDA) and may be performed as a two-step process or as a one-step process in which cDNA copies of an RNA target sequence are generated and amplified concurrently. In the one-step process, rtSDA reaction conditions are such that a conventional reverse transcriptase and a DNA-dependent polymerase function together in a single reaction to produce cDNA and amplify it.

Abstract: Mycobacteriophage DS6A has been characterized and found to specifically infect all species of the TB complex, without any detectable infection of mycobacteria species other than those of the TB complex. DNA sequence analysis revealed several potential open reading frames, including one encoding a protein analogous to gp37 of mycobacteriophage L5 and a second encoding a protein with significant homology to the S. coelicolor DNA polymerase .beta. subunit. Based on the DNA sequence analysis, cloning sites can be identified for insertion of reporter genes, making DS6A useful as a reporter phage for specific detection and identification of species of the TB complex.

Abstract: Mycobacteriophage DS6A has been characterized and found to specifically infect all species of the TB complex, without any detectable infection of mycobacteria species other than those of the TB complex. DNA sequence analysis revealed several potential open reading frames, including one encoding a protein analogous to gp37 of mycobacteriophage L5 and a second encoding a protein with significant homology to the S. coelicolor DNA polymerase .beta. subunit. Based on the DNA sequence analysis, cloning sites can be identified for insertion of reporter genes, making DS6A useful as a reporter phage for specific detection and identification of species of the TB complex.

Abstract: Mycobacteriophage DS6A has been characterized and found to specifically infect all species of the TB complex, without any detectable infection of mycobacteria species other than those of the TB complex. DNA sequence analysis revealed several potential open reading frames, including one encoding a protein analogous to gp37 of mycobacteriophage L5 and a second encoding a protein with significant homology to the S. coelicolor DNA polymerase .beta. subunit. Based on the DNA sequence analysis, cloning sites can be identified for insertion of reporter genes, making DS6A useful as a reporter phage for specific detection and identification of species of the TB complex.

Abstract: Mycobacteriophage DS6A has been characterized and found to specifically infect all species of the TB complex, without any detectable infection of mycobacteria species other than those of the TB complex. DNA sequence analysis revealed several potential open reading frames, including one encoding a protein analogous to gp37 of mycobacteriophage L5 and a second encoding a protein with significant homology to the S. coelicolor DNA polymerase .beta. subunit. Based on the DNA sequence analysis, cloning sites can be identified for insertion of reporter genes, making DS6A useful as a reporter phage for specific detection and identification of species of the TB complex.

Abstract: This invention is directed to the storing of digital, information, This storage system comprises a number of layers of transparent or translucent material. In each layer there is a chemical or chemicals subject to change by being contacted with different electromagnetic wave lengths. For example, if there be eight layers then the chemical or chemicals in any layer is subject to be changed by an electromagnetic radiation of a wave length different than for any of the other seven layers. In this manner, with eight layers it is possible to have an eight bit byte. Actually, under premutations and combinations it is possible to have as many as eight bit bytes from the eight layers. It is conceivable that there may be more than eight layers such as sixteen layers of thirty-two layers. There is the possibility of storing large amounts of information in a small volumn.

Abstract: This invention is directed to the storing of digital information. This storage system comprises a number of layers of transparent or translucent material. In each layer there is a chemical or chemicals subject to change by being contacted with different electromagnetic wave lengths. For example, if there be eight layers then the chemical or chemicals in any layer is subject to be changed by an electromagnetic radiation of a wave length different than of the other seven layers. In this manner, with eight layers it is possible to have an eight bit byte. Actually, under premutations and combinations it is possible to have as many as eight bit bytes from the eight layers. It is conceivable that there may be more than eight layers such as sixteen layers of thirty-two layers. There is the possibility of storing large amounts of information in a small volume.

Abstract: This invention is directed to the storing of digital information. This storage system comprises a number of layers of transparent or translucent material. In each layer there is a chemical or chemicals subject to change by being contacted with different electromagnetic wave lengths. For example, if there be eight layers then the chemical or chemicals in any layer is subject to be changed by an electromagnetic radiation of a wave length different than for any of the other seven layers. In this manner, with eight layers it is possible to have an eight bit byte. Actually, under premutations and combinations it is possible to have as many as eight bit bytes from the eight layers. It is conceivable that there may be more than eight layers such as sixteen layers of thirty-two layers. There is the possibility of storing large amounts of information in a small volume.

Abstract: This invention is directed to the separation of electromagnetic radiation into a, plurality, of selective wave length bands or colors. The term color separation, broadly applied, is meant to be the separation of primary and secondary or complementary wave lengths or colors for the purpose of geometric imaging. Such color separation is achieved, substantially, instantaneously, without the loss of wave length energy or color intensity by a novel means of reflection, transmission and color filtration. The separated colors or selective wave length bands can be, substantially, instantaneously, recreated as a geometric image or can be recorded for later recreation as a geometric image such as by photographic or movie films or by tapes; lithographic plated or engravings. Also, the separated colors or selective wave length bands can be used in making printing plates, directly, without using film.

Abstract: This invention is directed to the separation of electromagnetic radiation into a, plurality, of selective wave length bands or colors. The term color separation, broadly applied, is meant to be the separation of primary and secondary or complementary wave lengths or colors for the purpose of geometric imaging. Such color separation is achieved, substantially, instantaneously, without the loss of wave length energy or color intensity by a novel means of reflection, transmission and color filtration. The separated colors or selective wave length bands can be, substantially, instantaneously, recreated as a geometric image or can be recorded for later recreation as a geometric image such as by photographic or movie films or by tapes; lithographic plated or engravings. Also, the separated colors or selective wave length bands can be used in making printing plates, directly, without using film.

Abstract: This invention is directed to the separation of electromagnetic radiation into a, plurality, of selective wave length bands or colors. The term color separation, broadly applied, is meant to be the separation of primary and secondary or complementary wave lengths or colors for the purpose of geometric imaging. Such color separation is achieved, substantially, instantaneously, without the loss of wave length energy or color intensity by a novel means of reflection, transmission and color filtration. The separated colors or selective wave length bands can be, substantially, instantaneously, recreated as a geometric image or can be recorded for later recreation as a geometric image such as by photographic or movie films or by tapes; lithographic plates or engravings. Also, the separated colors or selective wave length bands can be used in making printing plates, directly, without using film.

Abstract: A pivotally mounted closure means for a cylindrical can of the type from which a potable fluid is consumed. A collar member of resilient construction snugly engages the can about its periphery. An ear member projects in a radial direction from the collar member and provides two pivotal mounting means. The first pivotal mounting means is provided at the distal free end of the ear member and the second is spaced radially inwardly therefrom. A deflection plate depending to a closure member pivots about the first pivotal means responsive to deflection thereof by a consumer-actuated lever member that pivots about said second pivotal means.

Abstract: This invention is directed to the separation of electromagnetic radiation into a plurality of selective wave length bands or colors. The term color separation, broadly applied, is meant to be the separation of primary and secondary or complementary wave lengths or colors for the purpose of geometric imaging. Such color separation is achieved, substantially, instantaneously, without the loss of wave length energy or color intensity by a novel means of reflection, transmission and color filtration. The separated colors or selective wave length bands can be, substantially, instantaneously, recreated as a geometric image or can be recorded for later recreation as a geometric image such as by photographic or movie films or by tapes; lithographic plates or engravings. Also, the separated colors or selective wave length bands can be used in making printng plates, directly, without using film.