Patents by Inventor Robert E. Ruhfel

Robert E. Ruhfel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for drying dye-terminator sequencing reagents
    Patent number: 7407747
    Abstract: A dry composition comprising a nucleotide linked to a fluorescent dye is provided. A method of making a dry composition comprising the step of drying a solution comprising a nucleotide linked to a fluorescent dye is provided. A method is provided for performing a reaction on a nucleic acid substrate comprising: (a) providing a vessel containing a dried composition comprising a nucleotide linked to a fluorescent dye, and (b) adding to the vessel an aqueous solution and the nucleic acid substrate. A kit is provided for determining the sequence of a nucleic acid, the kit comprising a dry composition comprising a nucleotide linked to a fluorescent dye.
    Type: Grant
    Filed: October 15, 2002
    Date of Patent: August 5, 2008
    Assignee: Applera Corporation
    Inventors: Kathleen M. Perry, Robert E. Ruhfel, Sandra L. Spurgeon, Peter Ma
  • Method for drying dye-terminator sequencing reagents
    Publication number: 20040072167
    Abstract: A dry composition comprising a nucleotide linked to a fluorescent dye is provided. A method of making a dry composition comprising the step of drying a solution comprising a nucleotide linked to a fluorescent dye is provided. A method is provided for performing a reaction on a nucleic acid substrate comprising: (a) providing a vessel containing a dried composition comprising a nucleotide linked to a fluorescent dye, and (b) adding to the vessel an aqueous solution and the nucleic acid substrate. A kit is provided for determining the sequence of a nucleic acid, the kit comprising a dry composition comprising a nucleotide linked to a fluorescent dye.
    Type: Application
    Filed: October 15, 2002
    Publication date: April 15, 2004
    Inventors: Kathleen M. Perry, Robert E. Ruhfel, Sandra L. Spurgeon, Peter Ma