Abstract: A securing apparatus for selectively securing an ablating element of an ablation instrument proximate to a targeted region of a biological tissue. The securing apparatus includes a support base affixed to the ablation instrument relative the ablating element, and having a support face adapted to seat against the biological tissue proximate to the ablation element. The support base further defines a passage having one end communicably coupled to a vacuum source and an opposite end terminating at an orifice at the support face. The support face together with the biological tissue forms a hermetic seal thereagainst during operation of the vacuum source to secure the ablation instrument thereagainst. Essentially, the hermetic seal and the vacuum source cooperate to form a vacuum force sufficient to retain the ablation device against the biological tissue.

Abstract: A directional ablation instrument for ablation of a targeted tissue. The instrument includes a transmission line having a proximal portion suitable for connection to an electromagnetic energy source, and an elongated antenna device having a longitudinal axis and an end coupled to the transmission line. The antenna is adapted to generate an electric field sufficiently strong to cause tissue ablation of the targeted tissue. An elongated support assembly includes a central axis, and an ablation surface extending longitudinally along an exterior surface portion of the support assembly. The support assembly is configured to receive the antenna device in the ablation surface such that the longitudinal axis of the antenna device is off-set from the support assembly central axis. Further, the antenna device is oriented toward the surface portion for positioning of the antenna device substantially adjacent to or in contact with the targeted tissue during operable use.

Abstract: A catheter system with an enhanced steering system, allowing for positioning the distal portion of the catheter proximate to a desired biological target tissue site, is provided. The system includes an elongated tubular member having a steerable distal end configured to deflect, or otherwise direct, and properly position at least a portion of the distal end comprising an ablation device during a surgical procedure allowing for the placement of the deflected portion adjacent or proximate to the target tissue surface. The steering system may alternatively be incorporated into a separate guiding catheter as part of the catheter system.

Abstract: A securing apparatus for selectively securing an ablating element of an ablation instrument proximate to a targeted region of a biological tissue. The securing apparatus includes a support base affixed to the ablation instrument relative the ablating element, and having a support face adapted to seat against the biological tissue proximate to the ablation element. The support base further defines a passage having one end communicably coupled to a vacuum source and an opposite end terminating at an orifice at the support face. The support face together with the biological tissue forms a hermetic seal thereagainst during operation of the vacuum source to secure the ablation instrument thereagainst. Essentially, the hermetic seal and the vacuum source cooperate to form a vacuum force sufficient to retain the ablation device against the biological tissue.

Abstract: An ablation instrument having a flexible portion at or near the distal portion of the instrument, is provided. The instrument includes an elongated tubular member having a steerable distal end configured to deflect, or otherwise direct, and properly position at least a portion of the distal portion, comprising an ablation device, during an ablation procedure. The instrument further includes a deflectable member which cooperates with the steering system allowing for the proper placement of the ablation device adjacent or proximate to the target tissue surface. The steering system may alternatively be incorporated into a separate guiding catheter as part of the catheter system.

Abstract: A catheter system with an enhanced steering system, allowing for positioning the distal portion of the catheter proximate to a desired biological target tissue site, is provided. The system includes an elongated tubular member having a steerable distal end configured to deflect, or otherwise direct, and properly position at least a portion of the distal end comprising an ablation device during a surgical procedure allowing for the placement of the deflected portion adjacent or proximate to the target tissue surface. The steering system may alternatively be incorporated into a separate guiding catheter as part of the catheter system.

Abstract: An ablation instrument having a flexible portion at or near the distal portion of the instrument, is provided. The instrument includes an elongated tubular member having a steerable distal end configured to deflect, or otherwise direct, and properly position at least a portion of the distal portion, comprising an ablation device, during an ablation procedure. The instrument further includes a deflectable member which cooperates with the steering system allowing for the proper placement of the ablation device adjacent or proximate to the target tissue surface. The steering system may alternatively be incorporated into a separate guiding catheter as part of the catheter system.

Abstract: A securing apparatus for selectively securing an ablating element of an ablation instrument proximate to a targeted region of a biological tissue. The securing apparatus includes a support base affixed to the ablation instrument relative the ablating element, and having a support face adapted to seat against the biological tissue proximate to the ablation element. The support base further defines a passage having one end communicably coupled to a vacuum source and an opposite end terminating at an orifice at the support face. The support face together with the biological tissue forms a hermetic seal thereagainst during operation of the vacuum source to secure the ablation instrument thereagainst. Essentially, the hermetic seal and the vacuum source cooperate to form a vacuum force sufficient to retain the ablation device against the biological tissue.

Abstract: A directional ablation instrument for ablation of a targeted tissue. The instrument includes a transmission line having a proximal portion suitable for connection to an electromagnetic energy source, and an elongated antenna device having a longitudinal axis and an end coupled to the transmission line. The antenna is adapted to generate an electric field sufficiently strong to cause tissue ablation of the targeted tissue. An elongated support assembly includes a central axis, and an ablation surface extending longitudinally along an exterior surface portion of the support assembly. The support assembly is configured to receive the antenna device in the ablation surface such that the longitudinal axis of the antenna device is off-set from the support assembly central axis. Further, the antenna device is oriented toward the surface portion for positioning of the antenna device substantially adjacent to or in contact with the targeted tissue during operable use.

Abstract: A directional ablation instrument for ablation of a targeted tissue. The instrument includes a transmission line having a proximal portion suitable for connection to an electromagnetic energy source, and an elongated antenna device having a longitudinal axis and an end coupled to the transmission line. The antenna is adapted to generate an electric field sufficiently strong to cause tissue ablation of the targeted tissue. An elongated support assembly includes a central axis, and a ablation surface extending longitudinally along an exterior surface portion of the support assembly. The support assembly is configured to receive the antenna device in the ablation surface such that the longitudinal axis of the antenna device is offset from the support assembly central axis. Further, the antenna device is oriented toward the surface portion for positioning of the antenna device substantially adjacent to or in contact with the targeted tissue during operable use.

Abstract: A directional ablation instrument for ablation of a targeted tissue. The instrument includes a transmission line having a proximal portion suitable for connection to an electromagnetic energy source, and an elongated antenna device having a longitudinal axis and an end coupled to the transmission line. The antenna is adapted to generate an electric field sufficiently strong to cause tissue ablation of the targeted tissue. An elongated support assembly includes a central axis, and a ablation surface extending longitudinally along an exterior surface portion of the support assembly. The support assembly is configured to receive the antenna device in the ablation surface such that the longitudinal axis of the antenna device is off-set from the support assembly central axis. Further, the antenna device is oriented toward the surface portion for positioning of the antenna device substantially adjacent to or in contact with the targeted tissue during operable use.

Abstract: A securing apparatus for selectively securing an ablating element of an ablation instrument proximate to a targeted region of a biological tissue. The securing apparatus includes a support base affixed to the ablation instrument relative the ablating element, and having a support face adapted to seat against the biological tissue proximate to the ablation element. The support base further defines a passage having one end communicably coupled to a vacuum source and an opposite end terminating at an orifice at the support face. The support face together with the biological tissue forms a hermetic seal thereagainst during operation of the vacuum source to secure the ablation instrument thereagainst. Essentially, the hermetic seal and the vacuum source cooperate to form a vacuum force sufficient to retain the ablation device against the biological tissue.

Abstract: A directional reflective shield assembly (25) is provided for a microwave ablation instrument (20) having an antenna (23) coupled to a transmission line (21). The antenna (23) is formed to generate an electric field sufficiently strong to cause tissue ablation. The shield assembly (25) includes a cradle device (26) disposed about the antenna (23) in a manner substantially shielding a surrounding area of the antenna (23) from the electric field radially generated therefrom. The cradle device (26) further provides a window portion (27) communicating with the antenna (23) which is strategically located relative the antenna to direct a majority of the field generally in a predetermined direction.

Abstract: A catheter which may be configured as a loop during an ablation procedure, and a method of use for such a catheter, are disclosed. According to one aspect of the present invention, an ablation catheter includes a flexible distal member arranged to inserted into a first vessel in the body of a patient, and an elongated flexible tubular member with a distal portion which is coupled to a proximal portion of the flexible distal member. The elongated flexible tubular member has a flexibility that is greater than or equal to the flexibility of the flexible distal member. The catheter also includes a transmission line which is at least partially disposed within the elongated flexible tubular member. A proximal end of the transmission line is suitable for connection to an electromagnetic energy source. The catheter further includes a transducer that is coupled to the transmission line, and is arranged to generate an electric field sufficiently strong to cause tissue ablation.

Abstract: A directional reflective shield assembly (25) is provided for a microwave ablation instrument (20) having an antenna (23) coupled to a transmission line (21). The antenna (23) is formed to generate an electric field sufficiently strong to cause tissue ablation. The shield assembly (25) includes a cradle device (26) disposed about the antenna (23) in a manner substantially shielding a surrounding area of the antenna (23) from the electric field radially generated therefrom. The cradle device (26) further provides a window portion (27) communicating with the antenna (23) which is strategically located relative the antenna to direct a majority of the field generally in a predetermined direction.

Abstract: A catheter which may be configured as a loop during an ablation procedure, and a method of use for such a catheter, are disclosed. According to one aspect of the present invention, a method for medical treatment using an ablation catheter system that includes a catheter with a transmission line disposed within a flexible tubular member and a transducer that is located at a central portion of the catheter that is proximal to a distal tip portion of the catheter involves introducing the catheter into a first vessel of the body of a patient and past the heart of the patient such that the distal tip portion of the catheter at least partially passes out of the body through a second vessel while the central portion of the catheter is positioned within a cardiac chamber.

Abstract: Methods and apparatus for connecting relatively small wires to standard size electrical connectors. An enlarged conductive region is formed on an end of the wire, the conductive region having an outer dimension adapted to be securely received in the connector, and the enlarged conductive region is covered with a nonconductive sleeve to electrically isolate the conductive region, the conductive region and nonconductive sleeve together defining an enlarged connector lead. The enlarged conductive region may be a conductive tube through which the wire is inserted and then spot welded, folded and/or crimped, or a multiple folded segment of the wire end, covered by a nonconductive shrink tube. The resulting enlarged connector lead may be received in a standard insulation displacement connector as part of a system for coupling the wire to electrical circuitry, the connector including a blade for piercing the nonconductive sleeve to electrically couple the wire to a terminal on the connector.

Abstract: A radiation transmitting sheath comprises a tubular body having a radiation guide extending axially therein. A coupler for attaching a radiation source is provided at the proximal end of the sheath. A dispersive tip for dispersing radiation from the radiation guide over a conical field is provided at the distal end of the sheath. Such sheaths are useful for providing illumination and endoscopic viewing methods and for providing sensitizing radiation in photodynamic therapy of body cavities.

Abstract: This invention is a surgical instrument and specifically is a catheter for treating a target site by delivering a controlled amount of a therapeutic or diagnostic agent (the target site being accessible by a tortuous path through the vasculature), the perfusion tip assembly on first catheter, and a process of using that catheter to deliver fluids to the selected vascular site.

Abstract: An optical apparatus functions as a laser catheter for removal, penetration or treatment of human tissue or other biotic material. The arrangement of the optical components, including the focal length of the lens and the spacing between the lens and the source of light is selected to yield an output beam having advantageous characteristics which are particularly suitable for medical laser treatment. Such characteristics include a relatively long beam throw, a long focal range, and a small output beam waist. A hollow tip, preferably conical in shape, is utilized to provide a tactile indicator as to the cutting action of the output beam.