Patents by Inventor Robert Eason
Robert Eason has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11185857Abstract: Techniques for making fluid flow devices are described. The technique is based on radiation-induced conversion of a radiation-sensitive substance from a first state to a second state. With adjustment of the radiation parameters such as power and scan speed we can control the depths of barriers that are formed within a substrate which can produce 3D flow paths. We have used this depth-variable patterning protocol for stacking and sealing of multilayer substrates, for assembly of backing layers for two-dimensional (2D) lateral flow devices and for fabrication of 3D devices. Since the 3D flow paths can be formed via a single laser-writing process by controlling the patterning parameters, this is a distinct improvement over other methods that require multiple complicated and repetitive assembly procedures.Type: GrantFiled: May 10, 2017Date of Patent: November 30, 2021Assignee: University of SouthamptonInventors: Robert Eason, Collin Sones, Ioannis Katis, Peijun He
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Publication number: 20190168217Abstract: Techniques for making fluid flow devices are described. The technique is based on radiation-induced conversion of a radiation-sensitive substance from a first state to a second state. With adjustment of the radiation parameters such as power and scan speed we can control the depths of barriers that are formed within a substrate which can produce 3D flow paths. We have used this depth-variable patterning protocol for stacking and sealing of multilayer substrates, for assembly of backing layers for two-dimensional (2D) lateral flow devices and for fabrication of 3D devices. Since the 3D flow paths can be formed via a single laser-writing process by controlling the patterning parameters, this is a distinct improvement over other methods that require multiple complicated and repetitive assembly procedures.Type: ApplicationFiled: May 10, 2017Publication date: June 6, 2019Applicant: University of SouthamptonInventors: Robert EASON, Collin SONES, loannis KATIS, Peijun HE
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Patent number: 9417233Abstract: Magnetic beads that include polyvalent ligands comprising various carbohydrates are described. Methods for fabricating such magnetic beads are also provided as well as methods of their use to capture and enrich pathogen cell population for subsequent culture, lysis and identification.Type: GrantFiled: January 22, 2015Date of Patent: August 16, 2016Assignee: LIFE TECHNOLOGIES CORPORATIONInventors: Aldrich Lau, Robert Eason, Maxim Brevnov, Handong Li, Kevin Hacker
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Patent number: 9228227Abstract: Methods for preparation of 2?,3?-dideoxynucleotides support structures, such as 2?,3?-dideoxyguanosine, 2?,3?-dideoxyadenosine, and 3?-deoxythymidine support structures are disclosed. Various methods of using such structures are also provided, such as their use for automated DNA synthesis and pyrophosphorolysis activated polymerization.Type: GrantFiled: February 5, 2014Date of Patent: January 5, 2016Assignee: Life Technologies CorporationInventors: Zhaochun Ma, Khairuzzaman Bashar Mullah, Robert Eason
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Publication number: 20150197743Abstract: Magnetic beads that include polyvalent ligands comprising various carbohydrates are described. Methods for fabricating such magnetic beads are also provided as well as methods of their use to capture and enrich pathogen cell population for subsequent culture, lysis and identification.Type: ApplicationFiled: January 22, 2015Publication date: July 16, 2015Inventors: Aldrich Lau, Robert Eason, Maxim Brevnov, Handong Li, Kevin Hacker
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Publication number: 20150045547Abstract: Methods for preparation of 2?,3?-dideoxynucleotides support structures, such as 2?,3?-dideoxyguanosine, 2?,3?-dideoxyadenosine, and 3?-deoxythymidine support structures are disclosed. Various methods of using such structures are also provided, such as their use for automated DNA synthesis and pyrophosphorolysis activated polymerization.Type: ApplicationFiled: February 5, 2014Publication date: February 12, 2015Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Zhaochun MA, Khairuzzaman Bashar Mullah, Robert Eason
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Patent number: 8945509Abstract: Magnetic beads that include polyvalent ligands comprising various carbohydrates are described. Methods for fabricating such magnetic beads are also provided as well as methods of their use to capture and enrich pathogen cell population for subsequent culture, lysis and identification.Type: GrantFiled: August 22, 2011Date of Patent: February 3, 2015Assignee: Life Technologies CorporationInventors: Aldrich Lau, Robert Eason, Maxim Brevnov, Handong Li, Kevin Hacker
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Publication number: 20120045767Abstract: Magnetic beads that include polyvalent ligands comprising various carbohydrates are described. Methods for fabricating such magnetic beads are also provided as well as methods of their use to capture and enrich pathogen cell population for subsequent culture, lysis and identification.Type: ApplicationFiled: August 22, 2011Publication date: February 23, 2012Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Aldrich LAU, Robert Eason, Maxim Brevnov, Handong Li, Kevin Hacker
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Publication number: 20110294122Abstract: Methods for preparation of 2?,3?-dideoxynucleotides support structures, such as 2?,3?-dideoxyguanosine, 2?,3?-dideoxyadenosine, and 3?-deoxythymidine support structures are disclosed. Various methods of using such structures are also provided, such as their use for automated DNA synthesis and pyrophosphorolysis activated polymerization.Type: ApplicationFiled: May 26, 2011Publication date: December 1, 2011Applicant: Life Technologies CorporationInventors: Zhaochun Ma, Khairuzzaman Bashar Mullah, Robert Eason
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Publication number: 20110014617Abstract: Methods and kits for detecting a target nucleic acid in a sample are described. In some embodiments, the sample to be analyzed includes a primer which hybridizes to at least a portion of the target nucleic acid, a probe having a first region which hybridizes to at least a portion of the target nucleic acid and a second region having a detectable label, a polymerase which extends the hybridized primer and an enzyme comprising nuclease activity that can cleave the hybridized hybridization probe to thereby release a labeled probe fragment. In some embodiments, the sample can then be contacted with a solid support comprising surface bound capture probes which can hybridize to the labeled probe fragment(s). These capture probes more readily bind to the probe fragment(s) than to the intact hybridization probe. The label can then be detected on the support surface. In this manner, improved discrimination between the probe fragments and the intact hybridization probes can be achieved.Type: ApplicationFiled: June 15, 2010Publication date: January 20, 2011Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Kristian Scaboo, Vissarion Aivazachvili, Timothy Liu, Robert Eason, Konrad Faulstich
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Publication number: 20080241838Abstract: Methods and kits for detecting a target nucleic acid in a sample are described. In some embodiments, the sample to be analyzed includes a primer which hybridizes to at least a portion of the target nucleic acid, a probe having a first region which hybridizes to at least a portion of the target nucleic acid and a second region having a detectable label, a polymerase which extends the hybridized primer and an enzyme comprising nuclease activity that can cleave the hybridized hybridization probe to thereby release a labeled probe fragment. In some embodiments, the sample can then be contacted with a solid support comprising surface bound capture probes which can hybridize to the labeled probe fragment(s). These capture probes more readily bind to the probe fragment(s) than to the intact hybridization probe. The label can then be detected on the support surface. In this manner, improved discrimination between the probe fragments and the intact hybridization probes can be achieved.Type: ApplicationFiled: December 28, 2007Publication date: October 2, 2008Applicant: APPLERA CORPORATION, APPLIED BIOSYSTEMS GROUPInventors: Kristian Scaboo, Vissarion Aivazachvili, Timothy Liu, Robert Eason, Konrad Faulstich
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Publication number: 20070099211Abstract: Methods for detecting a target polynucleotide sequences are provided that utilize a probe having a target-complementary segment and a detectable tag. By cleaving the detectable tab and associating the tag with a tag complement coupled to an electrode, an electrochemical signal can be detected that is related to the presence of the tag:tag complement complex.Type: ApplicationFiled: July 17, 2006Publication date: May 3, 2007Inventors: Vissarion Aivazachvili, Kristian Scaboo, Aldrich Lau, Konrad Faulstich, Robert Eason, John Van Camp, Timothy Liu
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Publication number: 20060104568Abstract: A method of inducing refractive index modifications in ferroelectric materials through the application of light in the form of scanned or patterned irradiation, removing the light to leave a permanent refractive index modified structure. This method can be used to design and engineer surface or near-surface structures in the form of waveguides, junctions, splitters and couplers, for application in optical circuitry, integrated optics, and active waveguide devices.Type: ApplicationFiled: July 21, 2003Publication date: May 18, 2006Inventors: Robert Eason, Sakellaris Mailis, Christos Riziotis
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Patent number: 6952307Abstract: A method of inducing a periodic variation of nonlinearity in a sample of ferroelectric material, comprises applying an electrically insulting mask to surface of the sample, applying an electric field across the sample to produce domain inversion in the sample, and removing the electric field when non-inverted regions of the sample remain only in the vicinity of the surface of the sample beneath parts of the surface covered by the mask. This method can be used to engineer accurate domain periods of submicron dimensions or larger which are confined to a surface region of the ferroelectric material, so that the poled material can be used to fabricate planar waveguide devices for nonlinear optical applications. In particular, the submicron periods can be exploited in the fabrication of one and two-dimensional photonic band gap devices.Type: GrantFiled: June 26, 2002Date of Patent: October 4, 2005Assignee: University of SouthamptonInventors: Vasilis Apostolopoulos, Alessandro Busacca, Sakellaris Mailis, Robert Eason
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Publication number: 20040207903Abstract: A method of inducing a periodic variation of nonlinearity in a sample of ferroelectric material, comprises applying an electrically insulting mask to surface of the sample, applying an electric field across the sample to produce domain inversion in the sample, and removing the electric field when non-inverted regions of the sample remain only in the vicinity of the surface of the sample beneath parts of the surface covered by the mask. This method can be used to engineer accurate domain periods of submicron dimensions or larger which are confined to a surface region of the ferroelectric material, so that the poled material can be used to fabricate planar waveguide devices for nonlinear optical applications. In particular, the submicron periods can be exploited in the fabrication of one and two-dimensional photonic band gap devices.Type: ApplicationFiled: May 26, 2004Publication date: October 21, 2004Inventors: Vasilis Apostolopoulos, Alessandro Busacca, Sakellaris Maillis, Robert Eason