Abstract: Described herein are methods that define cellular populations that are sensitive to RARA agonists and identify patient populations that will benefit from treatment with RARA agonists. The methods may comprise administering RARA agonists to patient populations.

Abstract: The invention provides novel devices to allow for the accelerated evaluation of the impacts of light exposure on the contents of the packaging system. Through this approach and using the methods described herein, it can be determined how the components of a complete package system perform collectively to influence its photoprotective performance enabling a first ever method to quantitate these impacts. The use of this device with the methods described herein will allow for package designs to be optimized for the photoprotection performances, for the impacts of packaging production defects to be explored, and for the influence of packaging form (e.g., surface area to volume ratio) to be determined. Such device capabilities allow a first ever means to provide simulated retail, isothermal light exposures to complete package systems.

Abstract: The invention provides novel methods to place a complete package system filled with a sample into a light exposure chamber as a complete unit with periodic monitoring of the contents of the packaging system. Through this approach, it can be determined how the components of a complete package system perform collectively to influence its photoprotective performance enabling a first ever method to quantitate these impacts. In turn this will allow for package designs to be optimized for the photoprotection performances, for the impacts of packaging production defects to be explored, and for the influence of packaging form (e.g., surface area to volume ratio) to be determined. Such capabilities allow a first ever means to optimize package systems for photoprotective performance.

Abstract: This invention provides methods for determining photosensitive properties of product materials by exposing the product materials to controlled light exposures and measuring for changes in the product materials to quantify light sensitivity.

Abstract: The invention provides cooling apparatus comprising: a solar heat collection means (2); two or more absorption refrigeration modules (1), each module being arranged to receive heat from the heat collection means and to re-circulate refrigerant through an evaporator (16); and means for putting a fluid to be cooled into thermal contact with each of the evaporators.

Abstract: The invention provides cooling apparatus comprising: a solar heat collection means (2); two or more absorption refrigeration modules (1), each module being arranged to receive heat from the heat collection means and to re-circulate refrigerant through an evaporator (16); and means for putting a fluid to be cooled into thermal contact with each of the evaporators.

Abstract: An apparatus and method for testing a component of a magnetic disk drive in which one or more drive-based components is used in the testing process. Each of the drive-based components is based on a corresponding one of the components of the magnetic disk drive. During testing, the component to be tested and at least one of the drive-based components are selectively engaged.

Abstract: The housing positioning system and method encompasses a residential subdivision having rectangular adjacent building lots including adjacent driveway areas perpendicular to a street and separated by a fence having a partial gradient. Dwelling units are placed on the lots so that a front wall of each dwelling unit faces the driveway area at approximately a 45° angle. A structure having an exterior wall disposed perpendicular to a centerline of the driveway areas includes a common internal wall to form separate garages servicing each of the respective dwelling units. Additionally, the structure may have a rear wall that is essentially parallel and proximate to a rear lot line. Alternatively, each dwelling unit may have an attached garage. For each property, a storage shed may be disposed adjacent to the garage. To limit yard maintenance, the driveway areas may wrap around a rear-facing wall of the dwellings.

Abstract: The invention includes an apparatus and method of selecting memory cells within a memory array. The method includes receiving a memory cell address. A column address and a row address are generated from the memory cell address. Row select lines or column select lines are pre-charged. A self-timed charging circuit is initiated to provide an adequate amount of time to charge a selected row, and to initiate elimination of static current flowing to unselected rows after a self-timed delay. The other of the row select lines or the column select lines are then pre-charged. Memory cells are selected based upon the column address and the row address. One of two states of the memory cells can be based upon sensing threshold voltages of sense lines that correspond with the selected memory cells.

Abstract: An apparatus and method for testing a component of a magnetic disk drive in which one or more drive-based components is used in the testing process. Each of the drive-based components is based on a corresponding one of the components of the magnetic disk drive. During testing, the component to be tested and at least one of the drive-based components are selectively engaged.

Abstract: A wireless podium microphone (1) incorporates a body pack transmitter (26). The microphone (1) includes a microphone element (6) that is interconnected to a weighted base (2) by a deformable neck (3). The base (2) includes a first cavity (10) for housing electrical components associated with the operation of the microphone element (6) and a second cavity (21) in which the transmitter (25) may be securely mounted. A keyway (31) receives and constrains a button (30) that is affixed to the transmitter housing (27). Parallel guides (36, 37) are formed within the second cavity (21) and prevent lateral movement of the transmitter (26). An antenna guide (43) is mounted to the base (2) and permits the transmitter antenna (28) to be oriented to the desired antenna polarization.

Abstract: The invention is a method and apparatus for planarizing a wafer. Discrete measurements are taken across the surface of the wafer at a desired spatial density. The measurements may be generated using a flash lamp to reflect a light signal off the surface of the wafer with a spectrometer analyzing the reflected light. A plurality of probes may be used at different locations to shorten the time necessary for taking measurements across the full front surface of the wafer and for allowing a plurality of areas to be sampled substantially simultaneously. A control system receives the measurements and their corresponding locations. The control system is then able to analyze the data looking for areas or bands on the front surface of the wafer that need an increase or decrease in material removal rate. The control system is then able to adjust one or more planarization parameters to improve the process for the current wafer or for future wafers.

Abstract: The invention includes an apparatus and method of selecting memory cells within a memory array. The method includes receiving a memory cell address. A column address and a row address are generated from the memory cell address. Row select lines or column select lines are pre-charged. A self-timed charging circuit is initiated to provide an adequate amount of time to charge a selected row, and to initiate elimination of static current flowing to unselected rows after a self-timed delay. The other of the row select lines or the column select lines are then pre-charged. Memory cells are selected based upon the column address and the row address. One of two states of the memory cells can be based upon sensing threshold voltages of sense lines that correspond with the selected memory cells.

Abstract: The invention includes a logic gate. The logic gate includes a charge holding device. A charging circuit selectively provides a predetermined charge for the charge holding device. A logic gate output is a function of charge on the charge holding device. The logic gate further includes a plurality of inputs. The plurality of inputs are electrically connected to the charge holding device so that the charge of the charge holding device is modified if any of the plurality of inputs is a first voltage potential. The invention also includes an address decoder. The address decoder includes a charge holding device. A charging circuit selectively provides a predetermined charge for the charge holding device. An address decoder output is a function of charge on the charge holding device. The address decoder further includes a plurality of address lines.

Abstract: The invention is a method and apparatus for planarizing a wafer. Discrete measurements are taken across the surface of the wafer at a desired spatial density. The measurements may be generated using a flash lamp to reflect a light signal off the surface of the wafer with a spectrometer analyzing the reflected light. A plurality of probes may be used at different locations to shorten the time necessary for taking measurements across the full front surface of the wafer and for allowing a plurality of areas to be sampled substantially simultaneously. A control system receives the measurements and their corresponding locations. The control system is then able to analyze the data looking for areas or bands on the front surface of the wafer that need an increase or decrease in material removal rate. The control system is then able to adjust one or more planarization parameters to improve the process for the current wafer or for future wafers.

Abstract: The invention includes an apparatus and method of selecting memory cells within a memory array. The method includes receiving a memory cell address. A column address and a row address are generated from the memory cell address. Row select lines or column select lines are pre-charged. A self-timed charging circuit is initiated to provide an adequate amount of time to charge a selected row, and to initiate elimination of static current flowing to unselected rows after a self-timed delay. The other of the row select lines or the column select lines are then pre-charged. Memory cells are selected based upon the column address and the row address. One of two states of the memory cells can be based upon sensing threshold voltages of sense lines that correspond with the selected memory cells.

Abstract: The invention includes a logic gate. The logic gate includes a charge holding device. A charging circuit selectively provides a predetermined charge for the charge holding device. A logic gate output is a function of charge on the charge holding device. The logic gate further includes a plurality of inputs. The plurality of inputs are electrically connected to the charge holding device so that the charge of the charge holding device is modified if any of the plurality of inputs is a first voltage potential. The invention also includes an address decoder. The address decoder includes a charge holding device. A charging circuit selectively provides a predetermined charge for the charge holding device. An address decoder output is a function of charge on the charge holding device. The address decoder further includes a plurality of address lines.

Abstract: The invention is a method and apparatus for planarizing a wafer. Discrete measurements are taken across the surface of the wafer at a desired spatial density. The measurements may be generated using a flash lamp to reflect a light signal off the surface of the wafer with a spectrometer analyzing the reflected light. A plurality of probes may be used at different locations to shorten the time necessary for taking measurements across the full front surface of the wafer and for allowing a plurality of areas to be sampled substantially simultaneously. A control system receives the measurements and their corresponding locations. The control system is then able to analyze the data looking for areas or bands on the front surface of the wafer that need an increase or decrease in material removal rate. The control system is then able to adjust one or more planarization parameters to improve the process for the current wafer or for future wafers.

Abstract: A fluid delivery system is provided for delivering a fluid to a polishing surface of a chemical mechanical polishing tool. The system includes a platen, manifold and slurry delivery conduit. The platen has a plurality of conduits for allowing a fluid to pass to the polishing surface. The manifold, through the use of a plurality of channels, controls the fluid distribution to the conduits in the platen. The channel cross-sectional area at substantially every point is greater than, preferably 1.5 to 2 times, the combined cross-sectional area of all the conduits being serviced by the channel. This results in the conduits being the most restrictive feature and a uniform pressure within the manifold. However, the volume of the channels should also be reduced as this reduces the time necessary for a fluid change over. The slurry delivery conduit communicates fluid from a fluid source to the channels in the manifold.

Abstract: The invention provides calibrated spectrometers in a multi-spectrometer system, where chemical mechanical polishing endpoint detection is an issue. In one aspect of the invention, a spectrometer is calibrated by selecting a filter slide having a predetermined light transmittance or reflectance variation with location (e.g. angular or linear displacement) on the slide. Light is incident on locations on the filter slide, and this incidence light is either transmitted or reflected. Transmitted or reflected light is received by a spectrometer, and the wavelength measured is compared with the known wavelength that corresponds to its location on the slide. The spectrometer is calibrated by normalizing the wavelength readings obtained at various locations on the slide with the known readings dictated by the reference slide. The spectrometers are also calibrated to a standard light source for intensity of light.