Abstract: The present disclosure relates to a novel, engineered enveloped vector that can be used for gene delivery. The engineered enveloped vector comprises an engineered envelope comprising: (a) a viral envelope protein and optionally, (b) a non-viral membrane-bound protein. The present disclosure also provides a method of making and using the engineered enveloped vector.

Abstract: The present disclosure relates to a novel, engineered enveloped vector that can be used for gene delivery. The engineered enveloped vector comprises an engineered envelope comprising: (a) a viral envelope protein and optionally, (b) a non-viral membrane-bound protein. The present disclosure also provides a method of making and using the engineered enveloped vector.

Abstract: The present disclosure provides novel nucleic acid-guided nucleases and methods of using the nucleases for genome editing. The present disclosure further provides a system for editing a target region in a genome comprising a nucleic acid-guided nuclease, a heterologous guide nucleic acid for complexing with the nucleic acid-guided nuclease, and an editing polynucleotide configured to bind to the target region.

Abstract: The present disclosure relates to a novel, engineered enveloped vector that can be used for gene delivery. The engineered enveloped vector comprises an engineered envelope comprising: (a) a viral envelope protein and optionally, (b) a non-viral membrane-bound protein. The present disclosure also provides a method of making and using the engineered enveloped vector.

Abstract: The present disclosure provides novel nucleic acid-guided nucleases and methods of using the nucleases for genome editing. The present disclosure further provides a system for editing a target region in a genome comprising a nucleic acid-guided nuclease, a heterologous guide nucleic acid for complexing with the nucleic acid-guided nuclease, and an editing polynucleotide configured to bind to the target region.

Abstract: Various examples of a motorcycle cover are provided. The cover can include a main body comprising a one or more layered material. The one or more layered material can include a flame resistant material, a heat reflective material, and a heat resistant material. The cover can also include one or more regions connected to and/or within the main body. The one or more regions can be configured to hold a stabilizing material to increase stability of the cover. The cover can be configured to protect the motorcycle within an inner side of the cover from a fire exterior to an outer side of the cover.

Abstract: A vehicle arresting device for rapidly disabling a moving vehicle includes a plurality of first wires and a plurality of second wires. Each second wire is coupled to each first wire. The first wires and the second wires are gridded and define a plurality of intersections. Each of a plurality of spikes, which is barbed, is coupled to and extends from a respective intersection. The spikes are configured to penetrate and couple to one or more tires of a vehicle passing over the spikes. The first wires and the second wires are rotationally compelled to entangle rotational components of the vehicle to arrest the vehicle.

Abstract: A sound emitting assembly inserted into a body or frame (106) or handgrip of a personal transport means (90) said assembly comprising: (i) a package comprising an electronically actuated sound generator, an electronic circuit to feed a signal to the sound generator and a source of stored electric power, and (ii) an actuating switch (118) separated from the package and linked to the package by an electric pathway (119) such that when the switch (118) is activated by the user, a sound is emitted from said body or frame (106) or handgrip distant from the switch (118).

Abstract: A sound emitting assembly that is inserted into a body or frame or handgrip of a personal transport means is provided. The assembly comprising a package comprising an electronically actuated sound generator, an electronic circuit to feed a signal to the sound generator and a source of stored electric power, and an actuating switch separated from the package and linked to the package by an electric pathway such that when the switch is activated by the user, a sound is emitted from said body or frame or handgrip distant from the switch.