Abstract: According to a general aspect, an apparatus includes a substrate, a plurality of microneedles, and a medicinal composition. The substrate has a surface. The plurality of microneedles is disposed on the surface of the substrate. The medicinal composition is configured to be delivered to a body of a person when the substrate is adhered to the body of the person. In some implementations, the medicinal composition is configured to help blood flow within bodily tissue of the person.

Abstract: A tissue removal device may include a handle. The device may include a sheath coupled to the handle. A first portion of the sheath may be within the handle. A second portion of the sheath may protrude from the handle. The sheath may include a passage. The device may include an end effector coupled to an end of the sheath. The device may include a drive member coupled to the handle and to the end effector. The drive member may extend through the passage of the sheath to the end effector. Actuation of the handle may move the end effector between an open state, for receiving material, and a closed state, for holding onto material, by causing relative movement between the drive member and the sheath. Further actuation of the handle may move the end effector relative to the handle while the end effector remains in the closed state.