Patents by Inventor Robert Edward MacKenzie

Robert Edward MacKenzie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS
    Publication number: 20090192138
    Abstract: The invention provides novel deazaxanthine and deazahypoxanthine compounds. The compounds may be useful in the therapy of diseases and conditions in which dipeptidylpeptidase-IV (DPP-IV) is implicated.
    Type: Application
    Filed: December 20, 2006
    Publication date: July 30, 2009
    Inventors: Daniel Kaspar Baeschlin, David Edward Clark, Stephen John Dunsdon, Garry Fenton, Amanda Fillmore, Neil Victor Harris, Christopher Higgs, Christopher Antony Hurley, Sussie Lerche Krintel, Robert Edward Mackenzie, Nils Ostermann, Finton Sirockin, Jonathan Mark Sutton
  • Indane derivatives
    Patent number: 6762199
    Abstract: The invention is directed to physiologically active compounds of general formula (I): wherein: R1 represents aryl, heteroaryl or a group R3—L2—Ar1—L3—; R2 represents hydrogen or lower alkyl; R3 represents aryl or heteroaryl; and Ar1 represents an optionally substituted saturated, partially saturated or fully unsaturated 8 to 10 membered bicyclic ring system containing at least one heteroatom selected from O, S or N; Y is carboxy or an acid bioisostere; and their corresponding N-oxides or prodrugs, and pharmaceutically acceptable salts and solvates of such compounds and their corresponding N-oxides or prodrugs. Such compounds have valuable pharmaceutical properties, in particular the ability to regulate the interaction of VCAM-1 and fibronectin with the integrin VLA-4 (&agr;4&bgr;1).
    Type: Grant
    Filed: August 28, 2002
    Date of Patent: July 13, 2004
    Assignee: Aventis Pharma Limited
    Inventors: Garry Fenton, Clive McCarthy, Robert Edward MacKenzie, Andrew David Morley
  • Indane derivatives
    Publication number: 20030199564
    Abstract: The invention is directed to physiologically active compounds of general formula (I): 1
    Type: Application
    Filed: August 28, 2002
    Publication date: October 23, 2003
    Inventors: Garry Fenton, Clive McCarthy, Robert Edward Mackenzie, Andrew David Morley