Patents by Inventor Robert Emil
Robert Emil has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220001028Abstract: Disclosed herein are compositions comprising AAV9 viral vectors and methods of using them to treat SMA patients, e.g., Type II and Type III Spinal Muscular Atrophy (SMA) patients.Type: ApplicationFiled: November 27, 2019Publication date: January 6, 2022Inventors: James Michael HATFIELD, Robert Emil HODGE, Douglas FELTNER, Joseph BALLEYDIER, Matthew MERIGGIOLI, Brian K. KASPAR, Allan Arman KASPAR
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Patent number: 11179404Abstract: The present application is directed to an aqueous pharmaceutical formulation comprising less than about 5% w/v sodium deoxycholate maintained at a pH sufficient to substantially inhibit precipitation of the sodium deoxycholate. Also disclosed herein, are methods for inhibiting precipitation of sodium deoxycholate in an aqueous solution comprising less than about 5% w/v of sodium deoxycholate, said method comprising maintaining pH of the solution of from at least about 8.0 to about 8.5.Type: GrantFiled: November 7, 2019Date of Patent: November 23, 2021Assignee: Allergan Sales, LLCInventors: Robert Emil Hodge, Jeffrey Douglas Webster
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Publication number: 20210317474Abstract: Methods for preparing and purifying viral particles, and compositions and uses comprising the same, are provided.Type: ApplicationFiled: November 1, 2018Publication date: October 14, 2021Inventors: Brian K. KASPAR, James Michael HATFIELD, Joseph BALLEYDIER, Allan Arman KASPAR, Robert Emil HODGE
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Publication number: 20210252021Abstract: The present application is directed to an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid, wherein the composition is maintained at a pH from about 8.1 to about 8.5 such that the composition is stabilized against precipitation. Also disclosed herein, are methods for stabilizing an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid against precipitation, said method comprising maintaining pH of the solution from about 8.1 to about 8.5.Type: ApplicationFiled: February 17, 2021Publication date: August 19, 2021Applicant: ALLERGAN SALES, LLCInventors: Robert Emil Hodge, Jeffrey Douglas Webster, Robert M. Moriarty
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Patent number: 10946030Abstract: The present application is directed to an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid, wherein the composition is maintained at a pH from about 8.1 to about 8.5 such that the composition is stabilized against precipitation. Also disclosed herein, are methods for stabilizing an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid against precipitation, said method comprising maintaining pH of the solution from about 8.1 to about 8.5.Type: GrantFiled: July 28, 2017Date of Patent: March 16, 2021Assignee: Allergan Sales, LLCInventors: Robert Emil Hodge, Jeffrey Douglas Webster, Robert M. Moriarty
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Publication number: 20200188414Abstract: The present application is directed to an aqueous pharmaceutical formulation comprising less than about 5% w/v sodium deoxycholate maintained at a pH sufficient to substantially inhibit precipitation of the sodium deoxycholate. Also disclosed herein, are methods for inhibiting precipitation of sodium deoxycholate in an aqueous solution comprising less than about 5% w/v of sodium deoxycholate, said method comprising maintaining pH of the solution of from at least about 8.0 to about 8.Type: ApplicationFiled: November 7, 2019Publication date: June 18, 2020Inventors: Robert Emil Hodge, Jeffrey Douglas Webster
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Patent number: 10500214Abstract: The present application is directed to an aqueous pharmaceutical formulation comprising less than about 5% w/v sodium deoxycholate maintained at a pH sufficient to substantially inhibit precipitation of the sodium deoxycholate. Also disclosed herein, are methods for inhibiting precipitation of sodium deoxycholate in an aqueous solution comprising less than about 5% w/v of sodium deoxycholate, said method comprising maintaining pH of the solution of from at least about 8.0 to about 8.5.Type: GrantFiled: August 14, 2018Date of Patent: December 10, 2019Assignee: ALLERGAN SALES, LLCInventors: Robert Emil Hodge, Jeffrey Douglas Webster
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Publication number: 20190038638Abstract: The present application is directed to an aqueous pharmaceutical formulation comprising less than about 5% w/v sodium deoxycholate maintained at a pH sufficient to substantially inhibit precipitation of the sodium deoxycholate. Also disclosed herein, are methods for inhibiting precipitation of sodium deoxycholate in an aqueous solution comprising less than about 5% w/v of sodium deoxycholate, said method comprising maintaining pH of the solution of from at least about 8.0 to about 8.5.Type: ApplicationFiled: August 14, 2018Publication date: February 7, 2019Applicant: Kythera Biopharmaceuticals, Inc.Inventors: Robert Emil HODGE, Jeffrey Douglas WEBSTER
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Patent number: 10071105Abstract: The present application is directed to an aqueous pharmaceutical formulation comprising less than about 5% w/v sodium deoxycholate maintained at a pH sufficient to substantially inhibit precipitation of the sodium deoxycholate. Also disclosed herein, are methods for inhibiting precipitation of sodium deoxycholate in an aqueous solution comprising less than about 5% w/v of sodium deoxycholate, said method comprising maintaining pH of the solution of from at least about 8.0 to about 8.5.Type: GrantFiled: July 14, 2017Date of Patent: September 11, 2018Assignee: Kythera Biopharmaceuticals, Inc.Inventors: Robert Emil Hodge, Jeffrey Douglas Webster
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Publication number: 20180015105Abstract: The present application is directed to an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid, wherein the composition is maintained at a pH from about 8.1 to about 8.5 such that the composition is stabilized against precipitation. Also disclosed herein, are methods for stabilizing an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid against precipitation, said method comprising maintaining pH of the solution from about 8.1 to about 8.5.Type: ApplicationFiled: July 28, 2017Publication date: January 18, 2018Applicant: Kythera Biopharmaceuticals, Inc.Inventors: Robert Emil Hodge, Jeffrey Douglas Webster, Robert M. Moriarty
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Publication number: 20180000835Abstract: The present application is directed to an aqueous pharmaceutical formulation comprising less than about 5% w/v sodium deoxycholate maintained at a pH sufficient to substantially inhibit precipitation of the sodium deoxycholate. Also disclosed herein, are methods for inhibiting precipitation of sodium deoxycholate in an aqueous solution comprising less than about 5% w/v of sodium deoxycholate, said method comprising maintaining pH of the solution of from at least about 8.0 to about 8.5.Type: ApplicationFiled: July 14, 2017Publication date: January 4, 2018Applicant: Kythera Biopharmaceuticals, Inc.Inventors: Robert Emil Hodge, Jeffrey Douglas Webster
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Patent number: 9737549Abstract: The present application is directed to an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid, wherein the composition is maintained at a pH from about 8.1 to about 8.5 such that the composition is stabilized against precipitation. Also disclosed herein, are methods for stabilizing an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid against precipitation, said method comprising maintaining pH of the solution from about 8.1 to about 8.5.Type: GrantFiled: November 26, 2013Date of Patent: August 22, 2017Assignee: Kythera Biopharmaceuticals, Inc.Inventors: Robert Emil Hodge, Jeffrey Douglas Webster, Robert M. Moriarty
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Patent number: 9724356Abstract: The present application is directed to an aqueous pharmaceutical formulation comprising less than about 5% w/v sodium deoxycholate maintained at a pH sufficient to substantially inhibit precipitation of the sodium deoxycholate. Also disclosed herein, are methods for inhibiting precipitation of sodium deoxycholate in an aqueous solution comprising less than about 5% w/v of sodium deoxycholate, said method comprising maintaining pH of the solution of from at least about 8.0 to about 8.5.Type: GrantFiled: February 7, 2014Date of Patent: August 8, 2017Assignee: Kythera Biopharmaceuticals, Inc.Inventors: Robert Emil Hodge, Jeffrey Douglas Webster
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Patent number: 9573607Abstract: A continuous scanning side laser detector system and method for real time, instantaneous accurate speed and direction measurement of a slow moving bulk material transport vehicle through a bulk material processing station.Type: GrantFiled: March 11, 2014Date of Patent: February 21, 2017Assignee: Kanawha Scales & Systems, Inc.Inventors: Duane Lee Bennett, Robert Emil Barker, Jr., James Troy Foley
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Patent number: 9525274Abstract: A corona discharge ignition system comprising a plurality of corona igniters is provided. The system includes a control and drive electronics unit for directing the energy from a power supply toward the corona igniters; and a single transformer disposed between the control and drive electronics unit and the plurality of corona igniters. A plurality of igniter switching units is connected to the control and drive electronics unit and each igniter switching unit is connected to a separate one of the corona igniters. Each igniter switching unit allows current to travel from the transformer to the one connected corona igniter when activated and prevents current from traveling from the transformer to the one connected corona igniter and from the one connected corona igniter toward the transformer when deactivated. Only one of the igniter switching units is activated at any given time during operation of the system.Type: GrantFiled: June 18, 2014Date of Patent: December 20, 2016Assignee: Federal-Mogul Ignition CompanyInventors: John Antony Burrows, Zdenek Svimbersky, Robert Emil Ratz
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Patent number: 9186364Abstract: The present application is directed to an aqueous pharmaceutical formulation comprising less than about 5% w/v sodium deoxycholate maintained at a pH sufficient to substantially inhibit precipitation of the sodium deoxycholate. Also disclosed herein, are methods for inhibiting precipitation of sodium deoxycholate in an aqueous solution comprising less than about 5% w/v of sodium deoxycholate, said method comprising maintaining pH of the solution of from at least about 8.0 to about 8.5.Type: GrantFiled: January 3, 2013Date of Patent: November 17, 2015Assignee: KYTHERA BIOPHARMACEUTICALS, INC.Inventors: Robert Emil Hodge, Jeffrey Douglas Webster
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Publication number: 20150311680Abstract: A corona discharge ignition system comprising a plurality of corona igniters is provided. The system includes a control and drive electronics unit for directing the energy from a power supply toward the corona igniters; and a single transformer disposed between the control and drive electronics unit and the plurality of corona igniters. A plurality of igniter switching units is connected to the control and drive electronics unit and each igniter switching unit is connected to a separate one of the corona igniters. Each igniter switching unit allows current to travel from the transformer to the one connected corona igniter when activated and prevents current from traveling from the transformer to the one connected corona igniter and from the one connected corona igniter toward the transformer when deactivated. Only one of the igniter switching units is activated at any given time during operation of the system.Type: ApplicationFiled: June 18, 2014Publication date: October 29, 2015Inventors: John Antony Burrows, Zdenek Svimbersky, Robert Emil
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Publication number: 20140313503Abstract: A continuous scanning side laser detector system and method for real time, instantaneous accurate speed and direction measurement of a slow moving bulk material transport vehicle through a bulk material processing station.Type: ApplicationFiled: March 11, 2014Publication date: October 23, 2014Applicant: Kanawha Scales & System, Inc.Inventors: Duane Lee Bennett, Robert Emil Barker, JR., James Troy Foley
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Publication number: 20140155364Abstract: The present application is directed to an aqueous pharmaceutical formulation comprising less than about 5% w/v sodium deoxycholate maintained at a pH sufficient to substantially inhibit precipitation of the sodium deoxycholate. Also disclosed herein, are methods for inhibiting precipitation of sodium deoxycholate in an aqueous solution comprising less than about 5% w/v of sodium deoxycholate, said method comprising maintaining pH of the solution of from at least about 8.0 to about 8.5.Type: ApplicationFiled: February 7, 2014Publication date: June 5, 2014Applicant: Kythera Biopharmaceuticals, Inc.Inventors: Robert Emil Hodge, Jeffrey Douglas Webster
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Publication number: 20140148429Abstract: The present application is directed to an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid, wherein the composition is maintained at a pH from about 8.1 to about 8.5 such that the composition is stabilized against precipitation. Also disclosed herein, are methods for stabilizing an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid against precipitation, said method comprising maintaining pH of the solution from about 8.1 to about 8.5.Type: ApplicationFiled: November 26, 2013Publication date: May 29, 2014Inventors: Robert Emil Hodge, Jeffrey Douglas Webster, Robert M. Moriarty