Patents by Inventor Robert Emil Hodge
Robert Emil Hodge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220001028Abstract: Disclosed herein are compositions comprising AAV9 viral vectors and methods of using them to treat SMA patients, e.g., Type II and Type III Spinal Muscular Atrophy (SMA) patients.Type: ApplicationFiled: November 27, 2019Publication date: January 6, 2022Inventors: James Michael HATFIELD, Robert Emil HODGE, Douglas FELTNER, Joseph BALLEYDIER, Matthew MERIGGIOLI, Brian K. KASPAR, Allan Arman KASPAR
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Patent number: 11179404Abstract: The present application is directed to an aqueous pharmaceutical formulation comprising less than about 5% w/v sodium deoxycholate maintained at a pH sufficient to substantially inhibit precipitation of the sodium deoxycholate. Also disclosed herein, are methods for inhibiting precipitation of sodium deoxycholate in an aqueous solution comprising less than about 5% w/v of sodium deoxycholate, said method comprising maintaining pH of the solution of from at least about 8.0 to about 8.5.Type: GrantFiled: November 7, 2019Date of Patent: November 23, 2021Assignee: Allergan Sales, LLCInventors: Robert Emil Hodge, Jeffrey Douglas Webster
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Publication number: 20210317474Abstract: Methods for preparing and purifying viral particles, and compositions and uses comprising the same, are provided.Type: ApplicationFiled: November 1, 2018Publication date: October 14, 2021Inventors: Brian K. KASPAR, James Michael HATFIELD, Joseph BALLEYDIER, Allan Arman KASPAR, Robert Emil HODGE
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Publication number: 20210252021Abstract: The present application is directed to an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid, wherein the composition is maintained at a pH from about 8.1 to about 8.5 such that the composition is stabilized against precipitation. Also disclosed herein, are methods for stabilizing an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid against precipitation, said method comprising maintaining pH of the solution from about 8.1 to about 8.5.Type: ApplicationFiled: February 17, 2021Publication date: August 19, 2021Applicant: ALLERGAN SALES, LLCInventors: Robert Emil Hodge, Jeffrey Douglas Webster, Robert M. Moriarty
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Patent number: 10946030Abstract: The present application is directed to an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid, wherein the composition is maintained at a pH from about 8.1 to about 8.5 such that the composition is stabilized against precipitation. Also disclosed herein, are methods for stabilizing an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid against precipitation, said method comprising maintaining pH of the solution from about 8.1 to about 8.5.Type: GrantFiled: July 28, 2017Date of Patent: March 16, 2021Assignee: Allergan Sales, LLCInventors: Robert Emil Hodge, Jeffrey Douglas Webster, Robert M. Moriarty
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Publication number: 20200188414Abstract: The present application is directed to an aqueous pharmaceutical formulation comprising less than about 5% w/v sodium deoxycholate maintained at a pH sufficient to substantially inhibit precipitation of the sodium deoxycholate. Also disclosed herein, are methods for inhibiting precipitation of sodium deoxycholate in an aqueous solution comprising less than about 5% w/v of sodium deoxycholate, said method comprising maintaining pH of the solution of from at least about 8.0 to about 8.Type: ApplicationFiled: November 7, 2019Publication date: June 18, 2020Inventors: Robert Emil Hodge, Jeffrey Douglas Webster
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Patent number: 10500214Abstract: The present application is directed to an aqueous pharmaceutical formulation comprising less than about 5% w/v sodium deoxycholate maintained at a pH sufficient to substantially inhibit precipitation of the sodium deoxycholate. Also disclosed herein, are methods for inhibiting precipitation of sodium deoxycholate in an aqueous solution comprising less than about 5% w/v of sodium deoxycholate, said method comprising maintaining pH of the solution of from at least about 8.0 to about 8.5.Type: GrantFiled: August 14, 2018Date of Patent: December 10, 2019Assignee: ALLERGAN SALES, LLCInventors: Robert Emil Hodge, Jeffrey Douglas Webster
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Publication number: 20190038638Abstract: The present application is directed to an aqueous pharmaceutical formulation comprising less than about 5% w/v sodium deoxycholate maintained at a pH sufficient to substantially inhibit precipitation of the sodium deoxycholate. Also disclosed herein, are methods for inhibiting precipitation of sodium deoxycholate in an aqueous solution comprising less than about 5% w/v of sodium deoxycholate, said method comprising maintaining pH of the solution of from at least about 8.0 to about 8.5.Type: ApplicationFiled: August 14, 2018Publication date: February 7, 2019Applicant: Kythera Biopharmaceuticals, Inc.Inventors: Robert Emil HODGE, Jeffrey Douglas WEBSTER
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Patent number: 10071105Abstract: The present application is directed to an aqueous pharmaceutical formulation comprising less than about 5% w/v sodium deoxycholate maintained at a pH sufficient to substantially inhibit precipitation of the sodium deoxycholate. Also disclosed herein, are methods for inhibiting precipitation of sodium deoxycholate in an aqueous solution comprising less than about 5% w/v of sodium deoxycholate, said method comprising maintaining pH of the solution of from at least about 8.0 to about 8.5.Type: GrantFiled: July 14, 2017Date of Patent: September 11, 2018Assignee: Kythera Biopharmaceuticals, Inc.Inventors: Robert Emil Hodge, Jeffrey Douglas Webster
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Publication number: 20180015105Abstract: The present application is directed to an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid, wherein the composition is maintained at a pH from about 8.1 to about 8.5 such that the composition is stabilized against precipitation. Also disclosed herein, are methods for stabilizing an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid against precipitation, said method comprising maintaining pH of the solution from about 8.1 to about 8.5.Type: ApplicationFiled: July 28, 2017Publication date: January 18, 2018Applicant: Kythera Biopharmaceuticals, Inc.Inventors: Robert Emil Hodge, Jeffrey Douglas Webster, Robert M. Moriarty
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Publication number: 20180000835Abstract: The present application is directed to an aqueous pharmaceutical formulation comprising less than about 5% w/v sodium deoxycholate maintained at a pH sufficient to substantially inhibit precipitation of the sodium deoxycholate. Also disclosed herein, are methods for inhibiting precipitation of sodium deoxycholate in an aqueous solution comprising less than about 5% w/v of sodium deoxycholate, said method comprising maintaining pH of the solution of from at least about 8.0 to about 8.5.Type: ApplicationFiled: July 14, 2017Publication date: January 4, 2018Applicant: Kythera Biopharmaceuticals, Inc.Inventors: Robert Emil Hodge, Jeffrey Douglas Webster
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Patent number: 9737549Abstract: The present application is directed to an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid, wherein the composition is maintained at a pH from about 8.1 to about 8.5 such that the composition is stabilized against precipitation. Also disclosed herein, are methods for stabilizing an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid against precipitation, said method comprising maintaining pH of the solution from about 8.1 to about 8.5.Type: GrantFiled: November 26, 2013Date of Patent: August 22, 2017Assignee: Kythera Biopharmaceuticals, Inc.Inventors: Robert Emil Hodge, Jeffrey Douglas Webster, Robert M. Moriarty
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Patent number: 9724356Abstract: The present application is directed to an aqueous pharmaceutical formulation comprising less than about 5% w/v sodium deoxycholate maintained at a pH sufficient to substantially inhibit precipitation of the sodium deoxycholate. Also disclosed herein, are methods for inhibiting precipitation of sodium deoxycholate in an aqueous solution comprising less than about 5% w/v of sodium deoxycholate, said method comprising maintaining pH of the solution of from at least about 8.0 to about 8.5.Type: GrantFiled: February 7, 2014Date of Patent: August 8, 2017Assignee: Kythera Biopharmaceuticals, Inc.Inventors: Robert Emil Hodge, Jeffrey Douglas Webster
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Patent number: 9186364Abstract: The present application is directed to an aqueous pharmaceutical formulation comprising less than about 5% w/v sodium deoxycholate maintained at a pH sufficient to substantially inhibit precipitation of the sodium deoxycholate. Also disclosed herein, are methods for inhibiting precipitation of sodium deoxycholate in an aqueous solution comprising less than about 5% w/v of sodium deoxycholate, said method comprising maintaining pH of the solution of from at least about 8.0 to about 8.5.Type: GrantFiled: January 3, 2013Date of Patent: November 17, 2015Assignee: KYTHERA BIOPHARMACEUTICALS, INC.Inventors: Robert Emil Hodge, Jeffrey Douglas Webster
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Publication number: 20140155364Abstract: The present application is directed to an aqueous pharmaceutical formulation comprising less than about 5% w/v sodium deoxycholate maintained at a pH sufficient to substantially inhibit precipitation of the sodium deoxycholate. Also disclosed herein, are methods for inhibiting precipitation of sodium deoxycholate in an aqueous solution comprising less than about 5% w/v of sodium deoxycholate, said method comprising maintaining pH of the solution of from at least about 8.0 to about 8.5.Type: ApplicationFiled: February 7, 2014Publication date: June 5, 2014Applicant: Kythera Biopharmaceuticals, Inc.Inventors: Robert Emil Hodge, Jeffrey Douglas Webster
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Publication number: 20140148429Abstract: The present application is directed to an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid, wherein the composition is maintained at a pH from about 8.1 to about 8.5 such that the composition is stabilized against precipitation. Also disclosed herein, are methods for stabilizing an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid against precipitation, said method comprising maintaining pH of the solution from about 8.1 to about 8.5.Type: ApplicationFiled: November 26, 2013Publication date: May 29, 2014Inventors: Robert Emil Hodge, Jeffrey Douglas Webster, Robert M. Moriarty
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Compositions comprising deoxycholic acid and salts thereof suitable for use in treating fat deposits
Patent number: 8653058Abstract: The present application is directed to an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid, wherein the composition is maintained at a pH from about 8.1 to about 8.5 such that the composition is stabilized against precipitation. Also disclosed herein, are methods for stabilizing an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid against precipitation, said method comprising maintaining pH of the solution from about 8.1 to about 8.5.Type: GrantFiled: August 10, 2011Date of Patent: February 18, 2014Assignee: Kythera Biopharmaceuticals, Inc.Inventors: Robert Emil Hodge, Jeffrey Douglas Webster, Robert M. Moriarty -
Patent number: 8367649Abstract: The present application is directed to an aqueous pharmaceutical formulation comprising less than about 5% w/v sodium deoxycholate maintained at a pH sufficient to substantially inhibit precipitation of the sodium deoxycholate. Also disclosed herein, are methods for inhibiting precipitation of sodium deoxycholate in an aqueous solution comprising less than about 5% w/v of sodium deoxycholate, said method comprising maintaining pH of the solution of from at least about 8.0 to about 8.5.Type: GrantFiled: December 12, 2011Date of Patent: February 5, 2013Assignee: Kythera Biopharmaceuticals, Inc.Inventors: Robert Emil Hodge, Jeffrey Douglas Webster
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Publication number: 20120258943Abstract: The present application is directed to an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid, wherein the composition is maintained at a pH from about 8.1 to about 8.5 such that the composition is stabilized against precipitation. Also disclosed herein, are methods for stabilizing an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid against precipitation, said method comprising maintaining pH of the solution from about 8.1 to about 8.5.Type: ApplicationFiled: August 10, 2011Publication date: October 11, 2012Inventors: Robert Emil Hodge, Jeffrey Douglas Webster, Robert M. Moriarty
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Publication number: 20120083481Abstract: The present application is directed to an aqueous pharmaceutical formulation comprising less than about 5% w/v sodium deoxycholate maintained at a pH sufficient to substantially inhibit precipitation of the sodium deoxycholate. Also disclosed herein, are methods for inhibiting precipitation of sodium deoxycholate in an aqueous solution comprising less than about 5% w/v of sodium deoxycholate, said method comprising maintaining pH of the solution of from at least about 8.0 to about 8.5.Type: ApplicationFiled: December 12, 2011Publication date: April 5, 2012Inventors: Robert Emil Hodge, Jeffrey Douglas Webster