Patents by Inventor Robert F. Baugh

Robert F. Baugh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8303993
    Abstract: The present relates to an autologous bioadhesive sealant composition, or fibrin glue prepared by a two-phase method, wherein all of the blood components for the bioadhesive sealant are derived from a patient to whom the bioadhesive sealant will be applied. A platelet rich plasma and a platelet poor plasma are formed by centrifuging a quantity of anticoagulated whole blood that was previously drawn from the patient. In one embodiment the platelet rich plasma is divided into two portions. In phase one, a compound that reverses the effect of the anticoagulant is added to the first portion and a clot is allowed to form. The clot is then triturated, and the resulting, serum containing autologous thrombin is collected. In phase two, the serum obtained from phase one is mixed with the second portion of the-platelet rich plasma to form the bioadhesive sealant of the invention.
    Type: Grant
    Filed: June 23, 2005
    Date of Patent: November 6, 2012
    Assignee: Ateriocyte Medical Systems, Inc.
    Inventors: Robert F. Baugh, Lisa M. Lim, Julie S. Johnston, John G. Rivera
  • Patent number: 7934603
    Abstract: The delivery system of the present invention is comprised of at least two chambers which store, individually, an activated blood component and an inactivated blood component. The first chamber comprises an activating agent and a filter which may be one in the same thus allowing the formed clot to be triturated thereby isolating the thrombin from the clot. The second chamber stores the inactivated blood component that when mixed with thrombin will produce a gel. The first or second chamber may further contain agents which are desired to be delivered to a specific site. The unique design of the delivery system allows for ease in operation of combining two agents at a specific time and place.
    Type: Grant
    Filed: May 2, 2005
    Date of Patent: May 3, 2011
    Assignee: Arteriocyte Medical Systems, Inc.
    Inventors: Julie S. Eaton, Robert F. Baugh, Lisa M. Lim, John G. Rivera, Victor D. Dolecek
  • Patent number: 7838039
    Abstract: Provided are methods of applying biological compositions, that is, autologous bioadhesive sealant compositions containing one or more biological agents, to an individual, wherein all the blood components used in preparing the composition are derived from the patient who is to receive the biological composition. In one embodiment, the method comprises obtaining a whole blood sample from an individual; forming an inactive platelet rich plasma from the whole blood sample; mixing a biological agent into the inactive platelet rich plasma; obtaining thrombin from the whole blood sample; mixing the thrombin into the inactive platelet rich plasma to form a biological composition; and applying the biological composition to the individual.
    Type: Grant
    Filed: January 27, 2005
    Date of Patent: November 23, 2010
    Assignee: Arteriocyte Medical Systems, Inc.
    Inventors: Robert F. Baugh, Lisa M. Lim, Julie S. Johnston, John G. Rivera
  • Patent number: 7811607
    Abstract: The present relates to an autologous bioadhesive sealant composition or fibrin glue prepared by a two-phase method, wherein all of the blood components for the bioadhesive sealant are derived from a patient to whom the bioadhesive sealant will be applied. A platelet rich plasma and a platelet poor plasma are formed by centrifuging a quantity of anticoagulated whole blood that was previously drawn from the patient. In one embodiment, the platelet rich plasma is divided into two portions. In phase one, a compound that reverses the effect of the anticoagulant is added to the first portion and a clot is allowed to form. The clot is then triturated, and the resulting serum containing autologous thrombin is collected. In phase two, the serum obtained from phase one is mixed with the second portion of the platelet rich plasma to form the bioadhesive sealant of the present invention.
    Type: Grant
    Filed: December 3, 2004
    Date of Patent: October 12, 2010
    Assignee: Arteriocyte Medical Systems, Inc.
    Inventors: Robert F. Baugh, Lisa M. Lim, Julie S. Johnston, John G. Rivera
  • Publication number: 20090026123
    Abstract: A system for the production of a blood component composition is provided. The system includes a centrifuge having a blood reservoir for receiving and separating a blood sample into multiple components; a dispenser disposed outside of the centrifuge having a first collection chamber containing an activation agent and a second collection chamber containing one or more medicinal agents; means for removing a first portion at least one separated blood component from the centrifuge to the first container and a second portion to the second collection chamber, wherein the first collection chamber activates the first portion and stores the resulting clot and thrombin; a filter for separating the thrombin from the clot; and a nozzle for entraining and mixing the thrombin with the second portion containing the one or more medicinal components.
    Type: Application
    Filed: August 18, 2008
    Publication date: January 29, 2009
    Inventors: Victor D. Dolecek, Robert F. Baugh, John G. Rivera, William F. McKay, Jeffery C. Marx
  • Patent number: 7413652
    Abstract: A system for the production of a blood component composition is provided. The system includes a centrifuge having a blood reservoir for receiving and separating a blood sample into multiple components; a dispenser disposed outside of the centrifuge having a first collection chamber containing an activation agent and a second collection chamber containing one or more medicinal agents; means for removing a first portion at least one separated blood component from the centrifuge to the first container and a second portion to the second collection chamber, wherein the first collection chamber activates the first portion and stores the resulting clot and thrombin; a filter for separating the thrombin from the clot; and a nozzle for entraining and mixing the thrombin with the second portion containing the one or more medicinal components.
    Type: Grant
    Filed: April 26, 2005
    Date of Patent: August 19, 2008
    Assignee: Arteriocyte Medical Systems, Inc.
    Inventors: Victor D. Dolecek, Robert F. Baugh, John G. Rivera, William F. McKay, Jeffery C. Marx
  • Patent number: 6955920
    Abstract: Apparatus and method for evaluating platelet functionality of a blood sample. A cartridge includes a plurality of test cells. Each cell receives an aliquot part of a blood sample. A measured amount of clotting reagent is provided in each cell. A measured amount of platelet activation reagent is provided in each cell, the amount of such reagent in each cell differing from the amount of such reagent in each other cell. The relative clotting times of the aliquot samples in the cells are determinative of the platelet functionality of the blood sample.
    Type: Grant
    Filed: June 11, 1999
    Date of Patent: October 18, 2005
    Assignee: Medtronic, Inc.
    Inventors: Robert F. Baugh, Carole G. Lane, Adrian C. Wilson
  • Patent number: 6942639
    Abstract: The delivery system of the present invention is comprised of at least two chambers which store, individually, an activated blood component and an inactivated blood component. The first chamber comprises an activating agent and a filter which may be one in the same thus allowing the formed clot to be triturated thereby isolating the thrombin from the clot. The second chamber stores the inactivated blood component that when mixed with thrombin will produce a gel. The first or second chamber may further contain agents which are desired to be delivered to a specific site. The unique design of the delivery system allows for ease in operation of combining two agents at a specific time and place.
    Type: Grant
    Filed: April 9, 2001
    Date of Patent: September 13, 2005
    Assignee: Medtronic, Inc.
    Inventors: Robert F. Baugh, Lisa M. Lim, Julie S. Eaton, John G. Rivera, Victor D. Dolecek
  • Patent number: 6899813
    Abstract: A system for the production of a blood component composition is provided. The system includes a centrifuge having a blood reservoir for receiving and separating a blood sample into multiple components; a dispenser disposed outside of the centrifuge having a first collection chamber containing an activation agent and a second collection chamber containing one or more medicinal agents; means for removing a first portion at least one separated blood component from the centrifuge to the first container and a second portion to the second collection chamber, wherein the first collection chamber activates the first portion and stores the resulting clot and thrombin; a filter for separating the thrombin from the clot; and a nozzle for entraining and mixing the thrombin with the second portion containing the one or more medicinal components.
    Type: Grant
    Filed: December 17, 2003
    Date of Patent: May 31, 2005
    Assignee: Medtronic, Inc.
    Inventors: Victor D. Dolecek, Robert F. Baugh, John G. Rivera, William F. McKay, Jeffery C. Marx
  • Patent number: 6830762
    Abstract: The present relates to an autologous bioadhesive sealant composition or fibrin glue prepared by a two-phase method, wherein all of the blood components for the bioadhesive sealant are derived from a patient to whom the bioadhesive sealant will be applied. A platelet rich plasma and a platelet poor plasma are formed by centrifuging a quantity of anticoagulated whole blood that was previously drawn from the patient. In one embodiment, the platelet rich plasma is divided into two portions. In phase one, a compound that reverses the effect of the anticoagulant is added to the first portion and a clot is allowed to form. The clot is then triturated, and the resulting serum containing autologous thrombin is collected. In phase two, the serum obtained from phase one is mixed with the second portion of the platelet rich plasma to form the bioadhesive sealant of the present invention.
    Type: Grant
    Filed: June 18, 2002
    Date of Patent: December 14, 2004
    Assignee: Medtronic, Inc.
    Inventors: Robert F. Baugh, Lisa M. Lim, Julie S. Johnston, John G. Rivera
  • Publication number: 20040213777
    Abstract: Provided are methods of applying biological compositions, that is, autologous bioadhesive sealant compositions containing one or more biological agents, to an individual, wherein all the blood components used in preparing the composition are derived from the patient who is to receive the biological composition. In one embodiment, the method comprises obtaining a whole blood sample from an individual; forming an inactive platelet rich plasma from the whole blood sample; mixing a biological agent into the inactive platelet rich plasma; obtaining thrombin from the whole blood sample; mixing the thrombin into the inactive platelet rich plasma to form a biological composition; and applying the biological composition to the individual.
    Type: Application
    Filed: May 18, 2004
    Publication date: October 28, 2004
    Inventors: Robert F. Baugh, Lisa M. Lim, Julie S. Johnston, John G. Rivera
  • Patent number: 6761856
    Abstract: An apparatus is provided for performing an activated clotting time test on a sample of blood containing platelets, the apparatus comprising a plurality of test cells, said cells being adapted for receiving an aliquot portion of said sample, wherein each of said cells comprises an anticoagulant and a platelet inactivating agent, and wherein at least one of said cells further comprises a clotting activator, wherein a clotting time is determined for each of said aliquot portions, and wherein a relative clotting time for each of said aliquot portions comprising the clotting activator is determined as compared to a reference clotting time for said at least one cell containing no clotting activator, wherein said relative clotting times in said cells are determinative of the clotting activation of said clotting activator.
    Type: Grant
    Filed: April 9, 2003
    Date of Patent: July 13, 2004
    Assignee: Medtronic, Inc.
    Inventors: Robert F. Baugh, Carole G. Lane, Adrian C. Wilson
  • Publication number: 20040132003
    Abstract: A system for the production of a blood component composition is provided. The system includes a centrifuge having a blood reservoir for receiving and separating a blood sample into multiple components; a dispenser disposed outside of the centrifuge having a first collection chamber containing an activation agent and a second collection chamber containing one or more medicinal agents; means for removing a first portion at least one separated blood component from the centrifuge to the first container and a second portion to the second collection chamber, wherein the first collection chamber activates the first portion and stores the resulting clot and thrombin; a filter for separating the thrombin from the clot; and a nozzle for entraining and mixing the thrombin with the second portion containing the one or more medicinal components.
    Type: Application
    Filed: December 17, 2003
    Publication date: July 8, 2004
    Inventors: Victor D. Dolecek, Robert F. Baugh, John G. Rivera, William F. McKay, Jeffery C. Marx
  • Patent number: 6719901
    Abstract: A system for the production of autologous thrombin, comprising a centrifuge including a blood reservoir for receiving and separating an autologous anticoagulated blood sample having multiple inactive blood components and means for removing at least one of said inactive blood components upon separation, and a dispenser having at least two collection chambers for receiving said at least one of said inactive blood components, wherein a first collection chamber activates a first portion of said inactive blood component and stores the resulting coagulated blood component comprising a clot and said autologous thrombin.
    Type: Grant
    Filed: April 9, 2001
    Date of Patent: April 13, 2004
    Assignee: Medtronic, Inc.
    Inventors: Victor D. Dolecek, Robert F. Baugh, John G. Rivera, William F. McKay, Jeffery C. Marx
  • Patent number: 6676902
    Abstract: A method and device for testing a sample of fresh whole blood. In particular the present invention provides a method and device for testing a sample of fresh whole blood to determine whether a patient would benefit from the administration of a blood factor (such as AT III.
    Type: Grant
    Filed: January 30, 2003
    Date of Patent: January 13, 2004
    Assignee: Medtronic, Inc.
    Inventors: Robert F. Baugh, Julie S. Johnston, Colleen Lutz
  • Publication number: 20030211008
    Abstract: An apparatus is provided for performing an activated clotting time test on a sample of blood containing platelets, the apparatus comprising a plurality of test cells, said cells being adapted for receiving an aliquot portion of said sample, wherein each of said cells comprises an anticoagulant and a platelet inactivating agent, and wherein at least one of said cells further comprises a clotting activator, wherein a clotting time is determined for each of said aliquot portions, and wherein a relative clotting time for each of said aliquot portions comprising the clotting activator is determined as compared to a reference clotting time for said at least one cell containing no clotting activator, wherein said relative clotting times in said cells are determinative of the clotting activation of said clotting activator.
    Type: Application
    Filed: April 9, 2003
    Publication date: November 13, 2003
    Inventors: Robert F. Baugh, Carole G. Lane, Adrian C. Wilson
  • Patent number: 6596180
    Abstract: A centrifuge system for the formation of an autologous platelet gel wherein all of the blood components for the gel are derived from a patient to whom the gel is to be applied. First a platelet rich plasma and a platelet poor plasma are formed by centrifuging a quantity of anticoagulated whole blood that was previously drawn from the patient. The platelet rich plasma or platelet poor plasma is then automatically drawn out of the centrifuge bag and proportioned into separate chambers in a dispenser. The first portion is activated where a clot is formed and thrombin is obtained. The thrombin is then latter mixed with the second portion to obtain a platelet gel.
    Type: Grant
    Filed: April 9, 2001
    Date of Patent: July 22, 2003
    Assignee: Medtronic, Inc.
    Inventors: Robert F. Baugh, Lisa M. Lim, Julie S. Johnston, John G. Rivera, Victor D. Dolecek
  • Publication number: 20030113929
    Abstract: A method and device for testing a sample of fresh whole blood. In particular the present invention provides a method and device for testing a sample of fresh whole blood to determine whether a patient would benefit from the administration of a blood factor (such as AT III.
    Type: Application
    Filed: January 30, 2003
    Publication date: June 19, 2003
    Inventors: Robert F. Baugh, Julie S. Johnston-Eaton, Colleen Lutz
  • Patent number: 6555064
    Abstract: An apparatus is provided for performing an activated clotting time test on a sample of blood containing platelets using a plunger sensor technique, the apparatus comprising a test cell, and wherein the test cell comprises an anticoagulant, a contact activator, and a predetermined amount of a platelet inactivating agent.
    Type: Grant
    Filed: March 16, 2001
    Date of Patent: April 29, 2003
    Assignee: Medtronic, Inc.
    Inventors: Robert F. Baugh, Carole G. Lane, Adrian C. Wilson
  • Patent number: 6555066
    Abstract: An apparatus for performing a platelet inhibition test on a sample of blood is provided, comprising a plurality of test cells, the cells being adapted for receiving an aliquot portion of the sample, wherein each of the cells comprises an anticoagulant and a clotting activator, and wherein at least one of the cells further comprises a platelet inactivating agent, wherein a clotting time is determined for each of the aliquot portions, and wherein a relative clotting time for each of the aliquot portions comprising the platelet inhibitor is determined as compared to a reference clotting time for a cell containing no platelet inhibitor, wherein the relative clotting times for the cells are determinative of the platelet inhibition of the sample.
    Type: Grant
    Filed: March 16, 2001
    Date of Patent: April 29, 2003
    Assignee: Medtronic, Inc.
    Inventors: Robert F. Baugh, Carole G. Lane, Adrian C. Wilson