Patents by Inventor Robert F. Czaja

Robert F. Czaja has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline salts of L or (S)-3-(3,4-dihydroxyphenyl)-2-methylalanine esters and process
    Patent number: 4914222
    Abstract: Crystalline salts of (R,S)-pivaloyloxyethyl esters of (S)-3-(3,4-dihydroxyphenyl)-2-methylalanine, processes for their preparation and pharmaceutical composition are disclosed.
    Type: Grant
    Filed: September 30, 1986
    Date of Patent: April 3, 1990
    Assignee: Merck & Co., Inc.
    Inventors: John Budavari, Robert F. Czaja, Edward J. J. Grabowski, William F. Shukis, Arthur J. Zambito
  • Process for preparing indenyl acetic acids
    Patent number: 4233457
    Abstract: This invention relates to an improved process for preparing 5-fluoro-2-methyl-1-(p-methylsulfinylbenzylidene)-3-indenyl acetic acid.
    Type: Grant
    Filed: May 17, 1979
    Date of Patent: November 11, 1980
    Assignee: Merck & Co., Inc.
    Inventors: Robert F. Czaja, Edward J. J. Grabowski
  • 7-(Amidinothio)acetamido-7-methoxy cephalosporins
    Patent number: 4121041
    Abstract: New 7-(Amidinothio)acetamido-7-methoxy-3-carbamoyloxymethyl-3-cephem-4-carboxy lic acid compounds are prepared which are useful as antibacterial agents, especially Pseudomonas.
    Type: Grant
    Filed: February 4, 1977
    Date of Patent: October 17, 1978
    Assignee: Merck & Co., Inc.
    Inventors: Robert F. Czaja, Edward J. J. Grabowski
  • Process for preparing indene acetic acids
    Patent number: 3970693
    Abstract: Process for preparing 5-fluoro-2-methyl-1-(p-methylsulfinylbenzylidene)-indene-3-acetic acid by reacting fluorobenzene with an acid halide, to form an indanone, reaction of the indanone with a methylthio (or methylsulfinyl) benzyl compound to form 5-fluoro-2-methyl-1-(p-methylthiobenzyl) or (p-methylsulfinylbenzyl)-indene and reacting said indene with a glyoxylic acid.This invention relates to new processes for preparing 5-fluoro-2-methyl-1-(p-methylsulfinylbenzylidene)-indene-3-acetic acid, to intermediates thereof and processes for said intermediates.
    Type: Grant
    Filed: July 5, 1974
    Date of Patent: July 20, 1976
    Assignee: Merck & Co., Inc.
    Inventors: Roger J. Tull, Robert F. Czaja, Richard F. Shuman, Seemon H. Pines
  • Chemical compounds and processes
    Patent number: 3953520
    Abstract: Haloalkyl derivatives of aromatic compounds are prepared via reaction with dialkoxy or aralkoxy alkanes in the presence of a Lewis acid.
    Type: Grant
    Filed: February 24, 1975
    Date of Patent: April 27, 1976
    Assignee: Merck & Co., Inc.
    Inventors: Robert F. Czaja, Seemon H. Pines, Newton L. Abramson
  • Indenylidene-3-acetic acid process for preparing indene acetic acids
    Patent number: 3944600
    Abstract: Process for preparing 5-fluoro-2-methyl-1-(p-methylsulfinylbenzylidene)-indene-3-acetic acid by reacting fluorobenzene with an acid halide, to form an indanone, reaction of the indanone with a methylthio (or methylsulfinyl)benzyl compound to form 5-fluoro-2-methyl-1-(p-methylthiobenzyl) or (p-methylsulfinylbenzyl)-indene and reacting said indene with a glyoxylic acid. The invention also relates to intermediates thereof and processes for said intermediates.
    Type: Grant
    Filed: September 30, 1974
    Date of Patent: March 16, 1976
    Assignee: Merck & Co., Inc.
    Inventors: Roger J. Tull, Robert F. Czaja, Richard F. Shuman, Seemon H. Pines