Abstract: The invention relates to cell sampling devices. In particular, the present invention relates to ingestible cell sampling devices for sampling cells in a subject, and methods of use for detecting abnormalities in a subject using the same.

Abstract: The invention relates to cell sampling devices. In particular, the present invention relates to ingestible cell sampling devices for sampling cells in a subject, and methods of use for detecting abnormalities in a subject using the same. Provided herein is technology for neoplasia screening, and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of cancer.

Abstract: A universal device for securing a catheter on a patient includes a base which optionally has at least one locating element for positioning or securing a catheter or catheter fitting of various shapes or sizes. The base has an opening and one or more restraining elements positioned on a surface of the base and extending over a portion of the opening. A retention plate includes locating elements for positioning or securing a catheter or catheter fitting of various shapes or sizes on the retention plate. Optionally, the retention plate may be movable. A support plate or similar device attached to the base holds the retention plate between the restraining elements and the support plate. A cover is connected to the base and may optionally have at least one capture element for restraining a catheter or catheter fitting of various shapes or sizes on the base or on the retention plate.

Abstract: A universal device for securing a catheter on a patient includes a base which optionally has at least one locating element for positioning or securing a catheter or catheter fitting of various shapes or sizes. The base has an opening and one or more restraining elements positioned on a surface of the base and extending over a portion of the opening. A retention plate includes locating elements for positioning or securing a catheter or catheter fitting of various shapes or sizes on the retention plate. Optionally, the retention plate may be movable. A support plate or similar device attached to the base holds the retention plate between the restraining elements and the support plate. A cover is connected to the base and may optionally have at least one capture element for restraining a catheter or catheter fitting of various shapes or sizes on the base or on the retention plate.

Abstract: The invention relates to an expandable stent comprising circumferentially adjacent modules. The modules comprise longitudinally adjacent slide-and-lock radial elements which permit one-way sliding of the radial elements from a collapsed diameter to an expanded/deployed diameter, but inhibit radial recoil from the expanded diameter.

Abstract: A universal device for securing a catheter on a patient includes a base which optionally has at least one locating element for positioning or securing a catheter or catheter fitting of various shapes or sizes. The base has an opening and one or more restraining elements positioned on a surface of the base and extending over a portion of the opening. A retention plate includes locating elements for positioning or securing a catheter or catheter fitting of various shapes or sizes on the retention plate. Optionally, the retention plate may be movable. A support plate or similar device attached to the base holds the retention plate between the restraining elements and the support plate. A cover is connected to the base and may optionally have at least one capture element for restraining a catheter or catheter fitting of various shapes or sizes on the base or on the retention plate.

Abstract: A securement device (10) secures a medical article (12) to the body of a patient and prevents longitudinal movement of the medical article (12) relative to the securement device (10). The securement device (10) includes a base portion (50) that is disposed over at least a part of a securement piece (20). The securement piece (20) forms a channel (19) configured to receive at least a portion of the medical article (12). The device (10) includes at least one actuator (40). The at least one actuator (40) is coupled with the securement piece (20) and configured to move the securement piece (20) between open position and a closed position. When the securement piece (20) is in the open position, it can receive at least a portion of the medical article (12). When the securement piece (20) is in the closed position, it prevents the received medical article (12) from moving in the longitudinal direction relative to the securement device (10).

Abstract: A universal device for securing a catheter on a patient includes a base which optionally has one or more locating elements for positioning or securing a catheter or catheter fitting of various shapes or sizes. The base optionally includes a recessed or flat receiving area defined by locating elements arranged to hold or receive a catheter or catheter fitting. Additional locating elements may be positioned elsewhere for receiving or holding a flange or wing of a catheter fitting. A cover is removably or permanently connected to the base and may optionally have one or more top openings for receiving tabs or extensions of a catheter fitting. The cover may optionally include one or more capture ridges for restraining a catheter or catheter fitting of various shapes or sizes on the base or on the retention plate. The cover may also include one or more tabs or contact bars.

Abstract: A system for securing a medical device such as a catheter or other medical article having various shapes or sizes in place on a patient includes a securing device. The securing device may optionally include a retainer having one or more receiving areas and one or more retention arms adjacent to the receiving areas. The securing device may also include a retention strap having a latching element that is removably connectable to a retention arm to securely hold a catheter in place. The retainer may optionally be connected to a base which may optionally be connected to an adhesive pad for easy attachment of the securing device to a patient.

Abstract: A medical article securement device holds a medical article such as a catheter in position upon the body of a patient and at least inhibits longitudinal movement of the medical article. The securement device includes a retainer, a pair of hinged actuators, and a pair of engagement members coupled with the hinged actuators. Movement of the actuators causes the engagement members to grip at least a portion of a medical article placed within the retainer so as to inhibit longitudinal movement of the medical article with respect to the retainer. The shape of the retainer inhibits lateral and transverse movement of the medical article with respect to a patient's skin.

Abstract: The invention relates to an expandable stent comprising circumferentially adjacent modules. The modules comprise longitudinally adjacent slide-and-lock radial elements which permit one-way sliding of the radial elements from a collapsed diameter to an expanded/deployed diameter, but inhibit radial recoil from the expanded diameter.

Abstract: An intraluminal, balloon expandable stent for implantation in a body lumen is disclosed. The present invention provides a lumen support stent with an unobstructed through-lumen for use in a blood vessel. A constraining mechanism is provided for securely maintaining the stent in the collapsed condition during delivery. The stent is preferably formed with a series of interconnected slide and lock mechanisms for permitting movement from a collapsed condition to an expanded condition and inhibiting radial recoil from the expanded condition. The stent may be formed from a shape memory alloy for providing crush-recovery after deployment.

Abstract: A universal securing device for holding catheters of various shapes and sizes and the like in place includes a base and cover. The cover may be connected to the base by a hinge which allows the cover to be lifted open or pushed down into a closed position, over a catheter fitting. The base may have locating elements configured and arranged to fit around catheter fittings of various sizes, and the locating elements prevent substantial movement of a catheter fitting and catheter in various dimensions. The cover may include capture elements which act to grip and compress the catheter fitting when the securing device is in a closed position, thus preventing substantial movement of a catheter fitting and catheter in various dimensions. The base may be attached to a patient with an adhesive pad attached to the bottom surface of the base.

Abstract: The invention relates to an expandable stent comprising circumferentially adjacent modules. The modules comprise longitudinally adjacent slide-and-lock radial elements which permit one-way sliding of the radial elements from a collapsed diameter to an expanded/deployed diameter, but inhibit radial recoil from the expanded diameter.

Abstract: A universal device for securing a catheter on a patient includes a base which optionally has one or more locating elements for positioning or securing a catheter or catheter fitting of various shapes or sizes. The base optionally includes a recessed or flat receiving area defined by locating elements arranged to hold or receive a catheter or catheter fitting. Additional locating elements may be positioned elsewhere for receiving or holding a flange or wing of a catheter fitting. A cover is removably or permanently connected to the base and may optionally have one or more top openings for receiving tabs or extensions of a catheter fitting. The cover may optionally include one or more capture ridges for restraining a catheter or catheter fitting of various shapes or sizes on the base or on the retention plate. The cover may also include one or more tabs or contact bars.

Abstract: A universal device for securing a catheter on a patient includes a base which optionally has one or more locating elements for positioning or securing a catheter or catheter fitting of various shapes or sizes. The base optionally includes a recessed or flat receiving area defined by locating elements arranged in any configuration suitable to hold or receive a catheter or catheter fitting, e.g., in a tapering or V shaped formation. Additional locating elements may be positioned elsewhere on the base for receiving or holding a flange or wing of a catheter fitting and preventing its movement in various directions. The base optionally has an angled surface to maintain the desired angle for catheters or catheter fittings in a patient. A cover is removably or permanently connected to the base and may optionally have one or more top openings for receiving tabs or extensions of a catheter fitting.

Abstract: A universal securing device for holding catheters of various shapes and sizes and the like in place includes a base and cover. The cover may be connected to the base by a hinge which allows the cover to be lifted open or pushed down into a closed position, over a catheter fitting. The base may have locating elements configured and arranged to fit around catheter fittings of various sizes, and the locating elements prevent substantial movement of a catheter fitting and catheter in various dimensions. The cover may include capture elements which act to grip and compress the catheter fitting when the securing device is in a closed position, thus preventing substantial movement of a catheter fitting and catheter in various dimensions. The base may be attached to a patient with an adhesive pad attached to the bottom surface of the base.

Abstract: A medical article securement device holds a medical article such as a catheter in position upon the body of a patient and at least inhibits longitudinal movement of the medical article. The securement device includes a retainer, a pair of hinged actuators, and a pair of engagement members coupled with the hinged actuators. Movement of the actuators causes the engagement members to grip at least a portion of a medical article placed within the retainer so as to inhibit longitudinal movement of the medical article with respect to the retainer. The shape of the retainer inhibits lateral and transverse movement of the medical article with respect to a patient's skin.

Abstract: A universal securing device for holding catheters of various shapes and sizes and the like in place includes a base and cover. The cover may be connected to the base by a hinge which allows the cover to be lifted open or pushed down into a closed position, over a catheter fitting. The base may have locating elements configured and arranged to fit around catheter fittings of various sizes, and the locating elements prevent substantial movement of a catheter fitting and catheter in various dimensions. The cover may include capture elements which act to grip and compress the catheter fitting when the securing device is in a closed position, thus preventing substantial movement of a catheter fitting and catheter in various dimensions. The base may be attached to a patient with an adhesive pad attached to the bottom surface of the base.

Abstract: A universal securing device for holding catheters of various shapes and sizes and the like in place includes a base and cover. The cover may be connected to the base by a hinge which allows the cover to be lifted open or pushed down into a closed position, over a catheter fitting. The base may have locating elements configured and arranged to fit around catheter fittings of various sizes, and the locating elements prevent substantial movement of a catheter fitting and catheter in various dimensions. The cover may include capture elements which act to grip and compress the catheter fitting when the securing device is in a closed position, thus preventing substantial movement of a catheter fitting and catheter in various dimensions. The base may be attached to a patient with an adhesive pad attached to the bottom surface of the base.