Patents by Inventor Robert F. Kelley

Robert F. Kelley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for the diagnosis and treatment of tumor
    Patent number: 9815905
    Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Grant
    Filed: September 29, 2014
    Date of Patent: November 14, 2017
    Assignee: Genentech, Inc.
    Inventors: Paul Polakis, Jyoti Asundi, Ron Firestein, Robert F. Kelley, Krista McCutcheon
  • ANTI-POLYUBIQUITIN ANTIBODIES AND METHODS OF USE
    Publication number: 20170240620
    Abstract: The invention provides anti-polyubiquitin antibodies and methods of using the same.
    Type: Application
    Filed: December 16, 2016
    Publication date: August 24, 2017
    Applicant: Genentech, Inc.
    Inventors: Vishva Dixit, Robert F. Kelley, Marissa L. Matsumoto
  • ANTI-CD3 ANTIBODIES AND METHODS OF USE
    Publication number: 20170204194
    Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
    Type: Application
    Filed: March 29, 2017
    Publication date: July 20, 2017
    Inventors: Xiaocheng CHEN, Mark S. DENNIS, Allen J. EBENS, Jr., Teemu T. JUNTTILA, Robert F. KELLEY, Mary A. MATHIEU
  • HUMANIZED ANTI-FACTOR D ANTIBODIES AND USES THEREOF
    Publication number: 20170166630
    Abstract: The invention relates to humanized anti-human Factor D monoclonal antibodies, their nucleic acid and amino acid sequences, the cells and vectors that harbor these antibodies and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation. These antibodies are useful for diagnostics, prophylaxis and treatment of disease.
    Type: Application
    Filed: July 29, 2016
    Publication date: June 15, 2017
    Inventors: Ling-Ling An, Sek Chung Fung, Robert F. Kelley, Henry B. Lowman, Sanjaya Singh, Herren Wu
  • ANTI-FACTOR D ANTIBODIES AND CONJUGATES
    Publication number: 20170145112
    Abstract: The invention provides anti-Factor D antibodies and conjugates and methods of using the same.
    Type: Application
    Filed: October 27, 2016
    Publication date: May 25, 2017
    Applicant: GENENTECH, INC.
    Inventors: Robert F. Kelley, Whitney Shatz, Devin Tesar, Justin M. Scheer, Michelle Dion
  • ANTI-HtrA1 ANTIBODIES AND METHODS OF USE THEREOF
    Publication number: 20170145113
    Abstract: The present invention provides anti-HtrA1 antibodies (including bispecific anti-HtrA1 anti-Factor D antibodies) and methods of making and using the same, for example, in methods of treating HtrA1-associated disorders, ocular disorders, and/or complement-associated disorders.
    Type: Application
    Filed: October 27, 2016
    Publication date: May 25, 2017
    Inventors: Robert F. KELLEY, Daniel K. KIRCHHOFER, Joyce LAI, Chingwei V. LEE, Wei-Ching LIANG, Michael T. LIPARI, Kelly M. LOYET, Tao SAI, Menno VAN LOOKEREN CAMPAGNE, Yan WU, Germaine FUH
  • ANTI-FACTOR D ANTIBODY VARIANT CONJUGATES AND USES THEREOF
    Publication number: 20170143843
    Abstract: The disclosure relates to antibody-polymer conjugates comprising one or more anti-Factor D antibody variants, their production and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation.
    Type: Application
    Filed: October 27, 2016
    Publication date: May 25, 2017
    Inventors: Philip E. Hass, Robert F. Kelley, Justin M. Scheer, Whitney Shatz, Devin Tesar, Menno van Lookeren Campagne
  • Anti-polyubiquitin antibodies and methods of use
    Patent number: 9556262
    Abstract: The invention provides anti-polyubiquitin antibodies and methods of using the same.
    Type: Grant
    Filed: February 20, 2015
    Date of Patent: January 31, 2017
    Assignee: Genentech, Inc.
    Inventors: Vishva Dixit, Robert F. Kelley, Marissa L. Matsumoto
  • ANTI-CLL-1 ANTIBODIES AND METHODS OF USE
    Publication number: 20160368994
    Abstract: The present invention relates to anti-CLL-1 antibodies including anti-CLL-1 antibodies comprising a CLL-1 binding domain and a CD3 binding domain (e.g., anti-CLL-1/CD3 T cell dependent bispecific (TDB) antibody) and methods of using the same.
    Type: Application
    Filed: June 14, 2016
    Publication date: December 22, 2016
    Applicant: Genentech, Inc.
    Inventors: Robert F. Kelley, Steven R. Leong, Wei-Ching Liang, Mary Mathieu, Andrew G. Polson, Bing Zheng, Xiaocheng Chen, Cecilia Pui Chi Chiu, Mark S. Dennis, Allen Ebens, Yan Wu
  • METHODS AND COMPOSITIONS FOR TARGETING POLYUBIQUITIN
    Publication number: 20160355577
    Abstract: Anti-K63-linked polyubiquitin monoclonal antibodies, and methods for using the antibodies, are provided.
    Type: Application
    Filed: May 12, 2016
    Publication date: December 8, 2016
    Applicant: GENENTECH, INC.
    Inventors: Robert F. Kelley, Marissa Matsumoto
  • Methods and compositions for targeting polyubiquitin
    Patent number: 9487578
    Abstract: Anti-polyubiquitin monoclonal antibodies, and methods for using the antibodies, are provided.
    Type: Grant
    Filed: November 14, 2013
    Date of Patent: November 8, 2016
    Assignee: Genentech, Inc.
    Inventors: Nathaniel C. Gordon, Robert F. Kelley, Anh Pham
  • ANTI-POLYUBIQUITIN ANTIBODIES
    Publication number: 20160304591
    Abstract: The invention provides anti-polyubiquitin antibodies and methods of using the same.
    Type: Application
    Filed: March 16, 2016
    Publication date: October 20, 2016
    Inventors: Robert F. Kelley, Vishva Dixit, Marissa L. Matsumoto
  • Methods and compositions for targeting polyubiquitin
    Patent number: 9365642
    Abstract: Anti-K63-linked polyubiquitin monoclonal antibodies, and methods for using the antibodies, are provided.
    Type: Grant
    Filed: June 5, 2015
    Date of Patent: June 14, 2016
    Assignee: Genentech, Inc.
    Inventors: Robert F. Kelley, Marissa L. Matsumoto
  • Anti-polyubiquitin antibodies
    Patent number: 9321844
    Abstract: The invention provides anti-polyubiquitin antibodies and methods of using the same.
    Type: Grant
    Filed: August 6, 2012
    Date of Patent: April 26, 2016
    Assignee: Genentech, Inc.
    Inventors: Robert F. Kelley, Vishva Dixit, Marissa L. Matsumoto
  • Anti-Factor D Antibody Variants and Uses Thereof
    Publication number: 20160017052
    Abstract: The invention relates to anti-Factor D antibody variants, their production and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation.
    Type: Application
    Filed: April 30, 2015
    Publication date: January 21, 2016
    Applicant: GENENTECH, INC.
    Inventors: Robert F. Kelley, Menno van Lookeren Campagne, Justin M. Scheer, Philip E. Hass, Devin Tesar
  • METHODS AND COMPOSITIONS FOR TARGETING POLYUBIQUITIN
    Publication number: 20160009791
    Abstract: Anti-K63-linked polyubiquitin monoclonal antibodies, and methods for using the antibodies, are provided.
    Type: Application
    Filed: June 5, 2015
    Publication date: January 14, 2016
    Applicant: GENENTECH, INC.
    Inventors: Robert F. Kelley, Marissa L. Matsumoto
  • Humanized Anti-Factor D Antibodies And Uses Thereof
    Publication number: 20160002353
    Abstract: The invention relates to humanized anti-human Factor D monoclonal antibodies, their nucleic acid and amino acid sequences, the cells and vectors that harbor these antibodies and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation. These antibodies are useful for diagnostics, prophylaxis and treatment of disease.
    Type: Application
    Filed: July 6, 2015
    Publication date: January 7, 2016
    Inventors: Ling-Ling An, Sek Chung Fung, Robert F. Kelley, Henry B. Lowman, Sanjaya Singh, Herren Wu
  • Humanized Anti-Factor D Antibodies And Uses Thereof
    Publication number: 20160002352
    Abstract: The invention relates to humanized anti-human Factor D monoclonal antibodies, their nucleic acid and amino acid sequences, the cells and vectors that harbor these antibodies and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation. These antibodies are useful for diagnostics, prophylaxis and treatment of disease.
    Type: Application
    Filed: July 6, 2015
    Publication date: January 7, 2016
    Inventors: Ling-Ling An, Sek Chung Fung, Robert F. Kelley, Henry B. Lowman, Sanjaya Singh, Herren Wu
  • Humanized Anti-Factor D Antibodies And Uses Thereof
    Publication number: 20150376295
    Abstract: The invention relates to humanized anti-human Factor D monoclonal antibodies, their nucleic acid and amino acid sequences, the cells and vectors that harbor these antibodies and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation. These antibodies are useful for diagnostics, prophylaxis and treatment of disease.
    Type: Application
    Filed: July 6, 2015
    Publication date: December 31, 2015
    Inventors: Ling-Ling An, Sek Chung Fung, Robert F. Kelley, Henry B. Lowman, Sanjaya Singh, Herren Wu
  • ANTI-POLYUBIQUITIN ANTIBODIES AND METHODS OF USE
    Publication number: 20150307602
    Abstract: The invention provides anti-polyubiquitin antibodies and methods of using the same.
    Type: Application
    Filed: February 20, 2015
    Publication date: October 29, 2015
    Inventors: Vishva Dixit, Robert F. Kelley, Marissa L. Matsumoto