Patents by Inventor Robert F. Parcell

Robert F. Parcell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of cis-(.+-.)-3,4-dihydro-N,N,2-trimethyl-2H-1-benzopyran-3-amine and intermediates produced thereby
    Patent number: 4203895
    Abstract: A process for the preparation of cis-(.+-.)-3,4-dihydro-N,N,2-trimethyl-2H-1-benzopyran-3-amine (I), a known antidepressant, is disclosed. The process of the invention is a multi-step process starting with 2-methyl-2H-1-benzopyran (II), which involves the production of novel intermediates (2.alpha.,3.beta.,4.alpha.)-(.+-.)-3,4-dihydro-2-methyl-4-(methylamino)-2H -1-benzopyran-3-ol (IV) and its hydrogen sulfate ester (V) as well as (1a.alpha.,2.beta.,7b.alpha.)-(.+-.)-1,1a,2,7b-tetrahydro-1,2-dimethyl[1]b enzopyrano[3,4-b]azirine (VI) and cis-(.+-.)-3,4-dihydro-N,2-dimethyl-2H-1-benzopyran-3-amine (VII). In the final step of the process, compound VII is methylated to form compound I.
    Type: Grant
    Filed: April 14, 1978
    Date of Patent: May 20, 1980
    Assignee: Warner-Lambert Company
    Inventors: Robert F. Parcell, Ivan C. Nordin