Patents by Inventor Robert Falotico

Robert Falotico has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted thienopyrans as antihypertensive agents
    Patent number: 5284857
    Abstract: Substituted thienopyrans and processes for preparing the thienopyrans are disclosed. The thienopyrans are useful as antihypertensive agents; antianginals are peripheral antivasoconstrictive agents.
    Type: Grant
    Filed: December 21, 1990
    Date of Patent: February 8, 1994
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Jeffery B. Press, Pauline Sanfilippo, James J. McNally, Robert Falotico
  • Substituted thienopyrans as antihypertensive agents
    Patent number: 5260453
    Abstract: Substituted thienopyrans and processes for preparing the thienopyrans are disclosed.
    Type: Grant
    Filed: November 5, 1990
    Date of Patent: November 9, 1993
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Jeffrey B. Press, Pauline Sanfilippo, James J. McNally, Robert Falotico
  • 6-7-dimethoxy-1,2-dihydro-2-arylquinazoline-3-oxides
    Patent number: 5030635
    Abstract: Novel 6,7-dimethoxy-1,2-dihydro-2-arylquinazoline-3-oxides and their synthesis are described. These novel compounds are cardiotonic agents and bronchodilating agents, and as such are useful for the treatment of heart failure and asthma.
    Type: Grant
    Filed: August 8, 1990
    Date of Patent: July 9, 1991
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Donald W. Combs, Robert Falotico, David M. Ritchie
  • Substituted thienopyrans
    Patent number: 5030736
    Abstract: Substituted thienopyrans and processes for preparing the thienopyrans are disclosed. The thienopyrans are useful as antihypertensive agents; antianginals are peripheral antivasoconstrictive agents.
    Type: Grant
    Filed: November 5, 1990
    Date of Patent: July 9, 1991
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Jeffery B. Press, Pauline Sanfilippo, James J. McNally, Robert Falotico
  • Substituted thienopyrans as antihypertensive agents
    Patent number: 4992435
    Abstract: Substituted thienopyrans and processes for preparing the thienopyrans are disclosed. The thienopyrans are useful as antihypertensive agents; antianginals are peripheral antivasoconstrictive agents.
    Type: Grant
    Filed: September 23, 1988
    Date of Patent: February 12, 1991
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Jeffery B. Press, Pauline Sanfilippo, James J. McNally, Robert Falotico
  • 6,7-dimethoxy-1,2-dihydro-2-arylquinazoline-3-oxides
    Patent number: 4963554
    Abstract: Novel 6,7-dimethoxy-1,2-dihydro-2-arylquinazoline-3-oxides and their synthesis are described. These novel compounds are cardiotonic agents and bronchodilating agents, and as such are useful for the treatment of heart failure and asthma.
    Type: Grant
    Filed: February 14, 1990
    Date of Patent: October 16, 1990
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Donald W. Combs, Robert Falotico, David M. Ritchie
  • Isoquinolinol compounds having cardiotonic and phosphodiesterase fraction III inhibiting properties and/or renal vasodilating properties
    Patent number: 4822800
    Abstract: Substituted 3-isoquinolinol compounds of the general formula ##STR1## that exhibit cardiotonic, renal vasodilating and phosphodiesterase fraction III properties are pharmacologically active in the treatment of cardiac conditions. Methods for synthesizing and using those compounds are described.
    Type: Grant
    Filed: June 9, 1986
    Date of Patent: April 18, 1989
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Robert Falotico, Ramesh M. Kanojia, Jeffery B. Press, Alfonso J. Tobia
  • Substituted quinazoline-3-oxides providing pharmacological activity
    Patent number: 4745118
    Abstract: Novel substituted quinazoline-3-oxides are disclosed as are methods of increasing cardiotonic activity and bronchodilation in which an unit dose of a composition containing an effective amount of a cardiotonic agent or a bronchodilating agent dispersed in a pharmaceutically acceptable carrier are administered to a mammalian host.
    Type: Grant
    Filed: June 5, 1986
    Date of Patent: May 17, 1988
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Donald W. Combs, Robert Falotico
  • 4-nitrogen substituted isoquinolinol compounds having cardiotonic, phosphodiesterase fraction III inhibiting properties and/or renal vasodilating properties
    Patent number: 4714705
    Abstract: Substituted 3-isoquinolinol compounds of the general formula ##STR1## that exhibit cardiotonic and/or phosphodiesterase fraction III inhibiting properties and/or renal vasodilating are pharmacologically active in the treatment of cardiac conditions. Methods for synthesizing and using those compounds are described.
    Type: Grant
    Filed: July 7, 1986
    Date of Patent: December 22, 1987
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Ramesh M. Kanojia, Robert Falotico, Alfonso J. Tobia, Jeffery B. Press
  • Substituted 3-(4-phenyl-1-piperazinyl)alkylquinazolin-2,4-(1H,3H) diones, methods of preparation, compositions and method of use
    Patent number: 4711883
    Abstract: Novel substituted-3-(4-phenyl-1-piperazinyl)alkyl quinazolin-2,4-(1H,3H)diones are described. These compounds are useful as antihypertensive agents.
    Type: Grant
    Filed: September 30, 1985
    Date of Patent: December 8, 1987
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Victor T. Bandurco, Charles F. Schwender, Robert Falotico, Alfonso J. Tobia
  • Substituted 5,6-dialkoxyquinazoline derivatives
    Patent number: 4672116
    Abstract: Quinazoline derivatives having an oxy substituent in 5 and 6 positions are described. The novel quinazoline derivatives are useful as cardiotonic agents.
    Type: Grant
    Filed: December 20, 1985
    Date of Patent: June 9, 1987
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Victor T. Bandurco, Stanley C. Bell, John H. Dodd, Robert Falotico, Charles F. Schwender, Alfonso J. Tobia
  • 5,6-dialkoxy-4-imino-2(1H)quinazolinone derivatives
    Patent number: 4668787
    Abstract: Quinazolinone derivatives having an oxy substituent in the 5- and 6-positions are disclosed. The quinazolinone derivatives are useful as cardiovascular agents.
    Type: Grant
    Filed: December 20, 1985
    Date of Patent: May 26, 1987
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Victor T. Bandurco, Stanley C. Bell, Robert Falotico, Charles F. Schwender, Alfonso J. Tobia
  • Substituted quinazolinediones
    Patent number: 4639518
    Abstract: The synthesis of 5,6-dioxy substituted quinazolinediones is described. The novel quinazolinediones are useful as cardiotonic agents.
    Type: Grant
    Filed: September 24, 1984
    Date of Patent: January 27, 1987
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Victor T. Bandurco, Stanley C. Bell, Donald W. Combs, Robert Falotico, Alfonso J. Tobia
  • 4-alkyl-5,6-methylenedioxy-2-1[H]-quinazolinones useful as cardiotonic agents
    Patent number: 4617392
    Abstract: 4-Alkyl-5,6-, 6,7-methylenedioxy-2-1[H]-quinazolinones are prepared from 2,3-methylenedioxyacetophenones. The 4-alkyl-5,6-, 6,7-methylenedioxy-2-1[H]-quinazolinones are active as cardiotonic agents.
    Type: Grant
    Filed: September 29, 1983
    Date of Patent: October 14, 1986
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Victor T. Bandurco, Stanley C. Bell, Donald W. Combs, Robert Falotico