Patents by Inventor Robert Feldman

Robert Feldman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR CANCER DETECTION
    Publication number: 20200081008
    Abstract: The present disclosure provides methods for cancer detection. The methods can comprise non-invasive detection of a biomarker from a subject. The methods can be used in combination with additional screening methods for greater accuracy of detection.
    Type: Application
    Filed: November 22, 2017
    Publication date: March 12, 2020
    Inventors: Robert FELDMAN, Melanie MAHTANI
  • Genes and proteins, and their use
    Publication number: 20090274717
    Abstract: According to the present invention, a series of genes are identified in Group B Streptococcus, the products of which may be associated with the outer surface of the organism. The genes, or functional fragments thereof, may be useful in the preparation of therapeutics, e.g. vaccines to immunize a patient against microbial infection.
    Type: Application
    Filed: August 17, 2007
    Publication date: November 5, 2009
    Applicant: Emergent Product Development UK Limited
    Inventors: Martin John Glenton Hughes, Joseph David Santangelo, Jonathan Douglas Lane, Robert Feldman, Joanne Christine Moore, Richard James Dobson, Paul Everest, Gordon Dougan, Rebecca Kerry Wilson
  • Genes and proteins, and their use
    Patent number: 7592011
    Abstract: A protein from Group B Streptococcus is shown to be an outer surface protein and is a useful target for antimicrobial therapy.
    Type: Grant
    Filed: September 17, 2004
    Date of Patent: September 22, 2009
    Assignee: Emergent Product Development UK Limited
    Inventors: Martin John Glenton Hughes, Joseph David Santangelo, Jonathan Douglas Lane, Robert Feldman, Joanne Christine Moore, Richard James Dobson, Paul Everest, Gordon Dougan, Rebecca Kerry Wilson
  • Outer surface proteins, their genes, and their use
    Publication number: 20080226641
    Abstract: According to the present invention, a series of genes are identified in Group B Streptococcus, the products of which may be located on the outer surface of the organism. The genes, or functional fragments thereof, may be useful in the preparation of therapeutics, e.g. vaccines for the immunization of a patient against microbial infection.
    Type: Application
    Filed: August 17, 2007
    Publication date: September 18, 2008
    Applicant: Emergent Product Development UK Limited
    Inventors: Martin John Glenton Hughes, Joseph David Santangelo, Jonathan Douglas Lane, Robert Feldman, Joanne Christine Moore, Richard James Dobson, Paul Everest, Caroline Joanne Henwood, Gordon Dougan, Rebecca Kerry Wilson
  • Genes and proteins, and their use
    Patent number: 7419672
    Abstract: According to the present invention, a series of genes are identified in Group B Streptococcus, the products of which may be associated with the outer surface of the organism. The genes, or functional fragments thereof, may be useful in the preparation of therapeutics, e.g. vaccines to immunize a patient against microbial infection.
    Type: Grant
    Filed: March 12, 2004
    Date of Patent: September 2, 2008
    Assignee: Emergent Product Development UK Limited
    Inventors: Martin John Glenton Hughes, Joseph David Santangelo, Jonathan Douglas Lane, Robert Feldman, Joanne Christine Moore, Richard James Dobson, Paul Everest, Gordon Dougan, Rebecca Kerry Wilson
  • GENES AND PROTEINS, AND THEIR USE
    Publication number: 20080181908
    Abstract: According to the present invention, a series of genes are identified in Group B Streptococcus, the products of which may be associated with the outer surface of the organism. The genes, or functional fragments thereof, may be useful in the preparation of therapeutics, e.g. vaccines to immunize a patient against microbial infection.
    Type: Application
    Filed: March 12, 2004
    Publication date: July 31, 2008
    Inventors: Martin John Glenton Hughes, Joseph David Santangelo, Jonathan Douglas Lane, Robert Feldman, Joanne Christine Moore, Richard James Dobson, Paul Everest, Gordon Dougan, Rebecca Kerry Wilson
  • NADP-dependent glyceraldehyde-3-phosphate dehydrogenase for therapeutic use
    Patent number: 7217415
    Abstract: According to the present invention, a series of genes are identified in Group B Streptococcus, the products of which may be located on the outer surface of the organism. The genes, or functional fragments thereof, may be useful in the preparation of therapeutics, e.g. vaccines for the immunization of a patient against microbial infection.
    Type: Grant
    Filed: December 22, 1999
    Date of Patent: May 15, 2007
    Assignee: Emergent Product Development UK Limited
    Inventors: Martin John Glenton Hughes, Joseph David Santangelo, Jonathan Douglas Lane, Robert Feldman, Joanne Christine Moore, Richard James Dobson, Paul Everest, Caroline Joanne Henwood, Gordon Dougan, Rebecca Kerry Wilson
  • Outer surface proteins, their genes, and their use
    Publication number: 20060104990
    Abstract: According to the present invention, a series of genes are identified in Group B Streptococcus, the products of which may be located on the outer surface of the organism. The genes, or functional fragments thereof, may be useful in the preparation of therapeutics, e.g. vaccines for the immunization of a patient against microbial infection.
    Type: Application
    Filed: December 29, 2005
    Publication date: May 18, 2006
    Inventors: Martin Hughes, Joseph Santangelo, Jonathan Lane, Robert Feldman, Joanne Moore, Richard Dobson, Paul Everest, Caroline Henwood, Gordon Dougan, Rebecca Wilson
  • Virulence genes, proteins, and their use
    Publication number: 20050232942
    Abstract: A series of genes from Streptococcus pyogenes are shown to encode products which are implicated in virulence. The identification of these genes therefore allows attuated microorganisms to be produced. Furthermore, the genes or their encoded products can be used in the manufacture of vaccines for therapeutic application.
    Type: Application
    Filed: June 3, 2005
    Publication date: October 20, 2005
    Inventors: Enda Clarke, Liqing Zhou, Jacqueline Shea, Robert Feldman, David Holden
  • Virulence genes and proteins, and their use
    Publication number: 20050142149
    Abstract: The present invention is based on the identification of a series of virulence genes in E. coli K1, the products of which may be implicated in the pathogenicity of the organisms. The identification of the genes allows them, or their expressed products, to be used in a number of ways to treat infection.
    Type: Application
    Filed: January 21, 2005
    Publication date: June 30, 2005
    Inventors: Helen Crooke, Enda Clarke, Paul Everest, Gordon Dougan, David Holden, Jacqueline Shea, Robert Feldman
  • Genes and proteins, and their use
    Publication number: 20050131210
    Abstract: A protein from Group B Steptococcus is shown to be an outer surface protein and is a useful target for antimicrobial therapy.
    Type: Application
    Filed: September 17, 2004
    Publication date: June 16, 2005
    Inventors: Martin Glenton Hughes, Joseph Santangelo, Jonathan Lane, Robert Feldman, Joanne Moore, Richard Dobson, Paul Everest, Gordon Dougan, Rebecca Wilson
  • Genes and proteins, and their use
    Patent number: 6890539
    Abstract: A protein from Group B Streptococcus is shown to be an outer surface protein and is a useful target for antimicrobial therapy.
    Type: Grant
    Filed: March 11, 2002
    Date of Patent: May 10, 2005
    Assignee: Microscience, Ltd.
    Inventors: Martin John Glenton Hughes, Joseph David Santangelo, Jonathan Douglas Lane, Robert Feldman, Joanne Christine Moore, Richard James Dobson, Paul Everest, Gordon Dougan, Rebecca Kerry Wilson
  • Genes and proteins and their use
    Patent number: 6812021
    Abstract: According to the present invention, a series of genes are identified in Group B Streptococcus, the products of which may be associated with the outer surface of the organism. The genes, or functional fragments thereof, may be useful in the preparation of therapeutics, e.g. vacaccines to immunize a patient against microbial infection.
    Type: Grant
    Filed: September 10, 2001
    Date of Patent: November 2, 2004
    Assignee: Microscience Limited
    Inventors: Martin John Glenton Hughes, Joseph David Santangelo, Jonathan Douglas Lane, Robert Feldman, Joanne Christine Moore, Richard James Dobson, Paul Everest, Gordon Dougan, Rebecca Kerry Wilson
  • Genes and proteins, and their use
    Publication number: 20030104000
    Abstract: A protein from Group B Streptococcus is shown to be an outer surface protein and is a useful target for antimicrobial therapy.
    Type: Application
    Filed: March 11, 2002
    Publication date: June 5, 2003
    Inventors: Martin John Glenton Hughes, Joseph David Santangelo, Jonathan Douglas Lane, Robert Feldman, Joanne Christine Moore, Richard James Dobson, Paul Everest, Gordon Dougan, Rebecca Kerry Wilson
  • Immunoassay for detecting group B streptococcus
    Patent number: 5225331
    Abstract: Immunoadsorbent combinations for the detection and diagnosis of group B streptococcus polysaccharide antigen, comprising an insoluble carrier, a capture agent having an affinity for specifically binding to the trirhamnose epitope of group B streptococcus antigen and having the formula .alpha.-L-Rhap(1.fwdarw.2)-.alpha.-L-Rhap(1.fwdarw.2).alpha.-Rhap- 1- wherein Rhap is rhamnose, and an antigen marker agent having an affinity for binding to monorhamnose epitope of group B streptococcus polysaccharide antigen of formula .alpha.-L-Rhap-1- when the group B streptococcus polysaccharide is bound to the carrier. An immunoassay method test kit and polyclonal antibody are also described.
    Type: Grant
    Filed: April 25, 1991
    Date of Patent: July 6, 1993
    Assignees: National Research Council of Canada, President and Fellows of Harvard College, The Brigham and Women's Hospital Inc.
    Inventors: Martial Lacroix, Robert Feldman, Dennis L. Kasper, Harold J. Jennings, Francis Michon, Robert J. Chalifour, Vince Pozsgay