Abstract: The invention relates to screening methods and test systems for the in vitro diagnosis and detection of an increased risk of vasospasm in a patient. In addition, the invention describes the use of GAPDH and/or Hsc70 to diagnose an increased risk of vasospasm. Also described is a method for identifying a pharmaceutically active substance for the prevention and/or treatment of cerebral vasospasm and a method for screening a substance library to identify a pharmaceutically active substance for the prevention and/or treatment of cerebral vasospasm. Pharmaceutically active substances and combination preparations are also disclosed.

Abstract: A strut and jounce bumper assembly is provided including a rate cup and jounce bumper that are capable of moving with the strut rod wherein the rate cup is provided with a concave spherical upper surface that engages a convex spherical surface of a strut mount bottom plate. The design allows use of a larger jounce bumper and striker in applications where the strut rod has large angular travel.

Abstract: A flexible driveline coupling is provided for interconnecting two rotational elements and includes an insert including a plurality of spaced mount portions that is overmolded with a second material such as microcellular urethane that provides improved torsional vibration isolation as well as reduced peak loads transmitted between the rotational elements. In addition, the design provides for reduced mass, reduced cost, and reduced noise transmission.

Abstract: A suspension system for use in a laundry washing machine to suspend a tub assembly from a base portion of a cabinet. The suspension system includes a support frame interconnected to an outer tub of the tub assembly and an isolation damper assembly for resiliently coupling the support frame to the base portion of the cabinet. The isolation damper assembly functions to allow limited lateral movement of the tub assembly relative to the cabinet while also providing a “return to center” feature. The isolation damper assembly is further operable to prevent rotation of the outer tub relative to the cabinet. Finally, the isolation damper assembly functions to absorb the vibration transmitted through the tub assembly to the support frame so as to minimize transmission of such vibration to the cabinet.