Abstract: An insulated pitched roofing system for a sloped deck in which an insulating sheet is adhered to the sloped deck or to a roofing substrate and the roof components are adhered to the insulating sheet with a polymer adhesive. The polymer adhesive is preferably a froth liquid polyurethane foam.

Abstract: A method of ameliorating or abrogating the effects of a neurodegenerative disorder, such as amyotrophic lateral sclerosis (ALS), includes administering a histone deacetylase (HDAC) inhibitor in a subject in need thereof. The HDAC inhibitor includes sodium butyrate or sodium phenylbutyrate.

Abstract: A method of ameliorating or abrogating the effects of a neurodegenerative disorder, such as Huntington's disease, includes administering a formulation including mitochondrial coenzyme Q10 in a subject in need thereof. The formulation includes Hydro-Q Sorb®, which is a complex of coenzyme Q10 and cyclodextrin.

Abstract: A method of ameliorating or abrogating the effects of a neurodegenerative disorder, such as Huntington's disease, includes administering a histone deacetylase (HDAC) inhibitor in a subject in need thereof. The HDAC inhibitor includes sodium butyrate.

Abstract: The present invention is an insulated pitched roof system for a sloped deck in which an insulating component is adhered to the sloped deck and the roof tiles are adhered to the insulating component with an adhesive, preferably a polymer adhesive. The insulating component includes a board or sheet material which is adhered to the roof deck. The insulating component is preferably adhered directly to the roof deck with a polymer adhesive. The insulating component preferably includes interlocking sides for forming a water tight connection between adjacently joined insulating components. Additionally, the insulating components include an end lap portion to form an overlapping portion between adjacent rows of insulating components. In a preferred embodiment, the overlapping portion is adhered together to form a unitary insulative and waterproof layer.

Abstract: The invention is directed to methods of preventing, delaying, or reducing motor neuron damage in an individual by administering to the individual a composition containing an extract of gingko biloba. The methods can be used to treat an individual having or at risk of having a condition characterized by motor neuron damage, e.g., amyotrophic lateral sclerosis. The invention also includes methods of preventing or reducing weight loss in an individual by administering to the individual a composition containing an extract of gingko biloba.