Abstract: Methods of preventing, inhibiting and/or decreasing protein deposits of a human amyloid protein and/or neuroinflammation in the central nervous system by reducing an amount of exposure to a pathogenic bacterial amyloid in the gastrointestinal tract are disclosed. Also disclosed are methods of preventing, inhibiting and/or treating a proteinopathy by reducing an amount of exposure to a pathogenic bacterial amyloid in the gastrointestinal tract.

Abstract: The present invention is directed toward folder embodiments with base plates and ring assemblies capable of being removably attached to the spine portion of the folder. The present invention is also directed toward folder embodiments with attachment means on the exterior outside of the binder/folder for attaching various objects.

Abstract: The present invention is directed toward folder embodiments with base plates and ring assemblies capable of being removably attached to the spine portion of the folder. The present invention is also directed toward folder embodiments with a magnetized surface and various recreational and educational representations on that magnetized surface.

Abstract: An illuminated notebook binder (10) having a front cover (12) and a rear cover (14) with each cover having inner ends (22) that are attached by an integral spine (28). Encircling the two ends of the spine (28) is a notebook closure flap (42) that is opened and closed by means of an encircling zipper (46). The inner surface (18) of the front cover (12) and/or the rear cover (14) includes a set of compartments (34), pockets (36) and pencil/pen retaining loops (38). The outer surface (16) of the front cover (12) includes indicia (50) that is illuminated by a set of light emitting diodes (DS1-DS5) that are activated by either a first switch (S1) or a second switch (S2). The switches are connected to an electronic control circuit (66) that controls the operation and illumination of the indicia (50). The circuit (66) is housed in an enclosure (64) that is attached to the inner surface (18) of the front cover (12) opposite the indicia (50).