Abstract: One variation of a method includes: accessing a first policy associated with a computer network; extracting a first entitlement from the first policy, the first entitlement granting permission to a first identity in the set of identities to access a first resource according to a first access level; accessing a first set of event data representing a first access attempt associated with the first resource by the first identity during a first time period, the first access attempt characterized by a second access level; detecting a deviation between the second access level and the first access level defined in the first entitlement; generating a second policy representing a second entitlement granting permission to the first identity to access the first resource according to the second access level in response to the deviation; and serving the second policy to an operator via an interface.

Abstract: Methods and assays for performing a lateral flow test are disclosed. A sample is applied to a receiving portion of a lateral flow device such that the sample flows to at least a first test zone and a second test zone. First and second signals levels at the first and second test zones over an assay period are monitored. If a first analyte of interest is present in the sample, the first analyte is labelled and the presence of labelled first analyte in the sample causes one of the first and second signals levels to increase during the assay period. A change between the first and second signal levels over a period of time during the assay period is monitored. The sample can be incubated prior to application to the receiving portion to provide homogeneity to labelling and therefore a substantially linear increase of the signal level at one of the test zones and a substantially constant signal level at the other one of the test zones.

Abstract: In some embodiments a diagnostic system is disclosed including a test device for performing diagnostic analysis of a biological sample from a human or animal body, the test device having an assay and a reader to analyse the sample and determine one or more biological conditions and to generate a result data signal containing information on the determination of the one or more biological conditions. The system also comprises a base device to releasably receive the test device, receive the result data signal from the test device, and display results of testing based on the received result data signal. In some embodiments a fluid receptacle is configured to be releasably retained to a test device, the test device comprising a housing, the housing having an engagement element for releasably retaining the fluid receptacle on an outer surface of the housing.

Abstract: The present disclosure relates generally to nanoparticle aggregates and to methods for preparing nanoparticle aggregates in a controlled manner The nanoparticle aggregates are useful in a variety of applications including detection and quantitation assays. In one illustrative example, the nanoparticle aggregates are particularly useful in medical diagnostic applications.

Abstract: A sampling device for collecting and dispensing a sample is disclosed, the sampling device including a sample collector having an absorbent portion configured to collect a sample and a receiving section configured to receive the sample collector after the collection of the sample. In one embodiment, the receiving section includes a dropper, the sample collector configured to be secured to the dropper, the dropper defining an internal chamber in which the absorbent portion of the sample collector is received when the sample collector is secured to the dropper; and a base releasably engaged with the dropper and at least partially housing the dropper, wherein the dropper is configured to be released from the base to allow dispensing of the sample from the dropper. In one embodiment, the absorbent portion interferes with a surface of an internal chamber of the receiving section. In one embodiment, a length adapter for the sample collector is employed and, in another embodiment, a desiccant housing is employed.

Abstract: A data processing method comprising obtaining a plurality of computer network security threat feeds from two or more computer threat detection systems; based upon computer network attack information in the computer network security threat feeds, determining a threat score that represents a severity of an actual or suspected attack on a particular host in a computer network; obtaining an asset value for the particular host that indicates a worth of the particular host, and updating the threat score based upon the asset value; mapping the updated threat score to one of a plurality of remediation actions, wherein a first remediation action is mapped when the updated threat score is low and a second, different remediation action is mapped when the updated threat score is high; based upon the updated threat score and the mapping, selecting and automatically performing one of the plurality of remediation actions on the particular host; wherein the method is performed by one or more special-purpose computing devices

Abstract: A delivery device for and method of delivering substance, the delivery device comprising: a delivery outlet from which substance is in use delivered; a gas chamber containing a gas and being of reducible volume, wherein a reduction in the volume of the gas chamber to a predeterminable volume acts to pressurize the contained gas to a predeterminable pressure; a seal element disposed between the gas chamber and the delivery outlet; and an opening mechanism configured, on reduction of the volume of the gas chamber to a predeterminable volume, to open the seal element, whereupon a gas flow from the gas chamber acts to deliver substance from the delivery outlet.

Abstract: A delivery device for and method of delivering substance, the delivery device comprising: a delivery outlet (7) from which substance (S) is in use delivered; a gas chamber (17) containing a gas and being of reducible volume, wherein a reduction in the volume of the gas chamber (17) to a predeterminable volume acts to pressurize the contained gas to a predeterminable pressure; a seal element (11) disposed between the gas chamber (17) and the delivery outlet (7); and an opening mechanism configured, on reduction of the volume of the gas chamber to a predeterminable volume, to open the seal element (11), whereupon a gas flow from the gas chamber (17) acts to deliver substance (S) from the delivery outlet (7).

Abstract: Reporter fragments, reporter components, and systems adapted to detect analytes in homogeneous in vitro assays are provided, such assays employing these systems, and methods of making and using same. Particular embodiments include isolated and purified reporter fragments displaying enhanced solubility, reduced aggregation, resistance to inhibitors, and enhanced suitability for use in homogeneous in vitro assays.

Abstract: A method for supplying power from a battery pack includes monitoring an output voltage of a battery pack, where the battery pack comprises a number of fractions and determining whether the output voltage is below a predetermined threshold. The method further includes adding at least one fraction of the number of fractions to the output voltage, when the output voltage is below the predetermined threshold and removing the at least one fraction, if previously added, when the output voltage is no longer below the predetermined threshold.

Abstract: A method for supplying power from a battery pack includes monitoring an output voltage of a battery pack, where the battery pack comprises a number of fractions and determining whether the output voltage is below a predetermined threshold. The method further includes adding at least one fraction of the number of fractions to the output voltage, when the output voltage is below the predetermined threshold and removing the at least one fraction, if previously added, when the output voltage is no longer below the predetermined threshold.

Abstract: Disclosed is a portable device for delivering a medicament or the like into the body of a human or animal subject, the device comprising: a medicament compartment containing the medicament or the like to be delivered; delivery means comprising an orifice through which the medicament or the like is expelled from the device; and an internal combustion engine which provides the motive force by which the medicament is expelled from the device.

Abstract: A detector for detecting cargo in a container has a controller block, a transmitter for transmitting light into the field of view, a receiver for receiving reflected light, and a threshold comparator for determining whether the received light meets a threshold for cargo detection. The receiver includes a DC block for removing effects of ambient light. The detector performs detection multiple times and averages the results, which can be compared with a previously stored condition of cargo presence or absence to increase the detection accuracy further.

Abstract: Disclosed is a portable device for delivering a medicament or the like into the body of a human or animal subject, the device comprising: a medicament compartment containing the medicament or the like to be delivered; delivery means comprising an orifice through which the medicament or the like is expelled from the device; and an internal combustion engine which provides the motive force by which the medicament is expelled from the device.

Abstract: A detector for detecting cargo in a container has a controller block, a transmitter for transmitting light into the field of view, a receiver for receiving reflected light, and a threshold comparator for determining whether the received light meets a threshold for cargo detection. The receiver includes a DC block for removing effects of ambient light. The detector performs detection multiple times and averages the results, which can be compared with a previously stored condition of cargo presence or absence to increase the detection accuracy further.

Abstract: A light projector is provided which includes an elliptical reflector, a first spherical retro-reflector, the first retro-reflector having an first aperture formed therein, the first aperture having a first diameter and a first center-point, a second spherical retro-reflector located between the elliptical reflector and the first retro-reflector, the second retro-reflector having a second aperture formed therein, the second aperture having a second diameter and a second center-point, the second diameter smaller than the first diameter, the first and second center-points lying along a common axis, and a light source, the light source located at a foci of the elliptical reflector, the light source lying along the common axis, the elliptical reflector reflecting light emitted by the light source, the reflected light passing through the first and second apertures, the first and second retro-reflectors being positioned so as to reflect light emitted by the light source back towards the light source.