Abstract: Disclosed herein are methods for reducing neuropathy and neuropathic symptoms and/or promoting neurogenesis, neuritogenesis, neuroprotection and neuroregeneration using saposin C-phospholipid compositions. Also disclosed are methods for treating cancer by administering a saposin C-phospholipid nanovesicle formulation and one or more antineoplastic agents or immune checkpoint inhibitors, and kits for the treatment of cancer comprising, in separate containers, (a) a saposin C-phospholipid pharmaceutical composition, and (b) a pharmaceutical composition containing an antineoplastic agent or a pharmaceutical composition containing an immune checkpoint inhibitor.

Abstract: A wireless transmit/receive unit (WTRU) comprising a receiver, a transmitter, and a processor, wherein the processor is configured to generate a Block Address Registration and Claiming (BARC) protocol data unit (PDU) including a BARC identifier, and an associated 4-bit state field, and further wherein the transmitter is configured to transmit the BARCPDU. The BARC identifier may include at least one of a claimable address block address (CABA), registerable address block identifier (RABI), or a proposed RABI (PRABI). The BARCPDU may be encoded as a IEEE 1722 message.

Abstract: Described herein are systems, methods, and instrumentalities associated with enabling a wireless transmit/receive unit (WTRU) to participate in multi-access edge computing (MEG) services. The WTRU may be a constrained WTRU, for example, in terms of computation, storage, and/or networking resources available to the WTRU. A function may be implemented on the WTRU to expose an interface to an MEG application on the WTRU, through which the MEG application may register with a network device such as an MEO host located at the edge of a mobile communication network and join an MEO service provided by the MEG host. A transport may be established between the WTRU and the MEG host to facilitate provision of the MEG service, and the transport may be modified and/or deleted, for example, based on mobility events at the WTRU and/or load conditions of the WTRU.

Abstract: In examples, a function (e.g., local federation (LF)) may be used in Edge Multi-access Edge Computing (EMEC) and Constrained Multi-access Edge Computing (CMEC) to discover available applications in EMEC and CMEC. The function may be referred to as LFE, for example, if used in EMEC. The function may be referred to as LFC, for example, if used in CMEC. In examples, one or more interfaces may be used between LF entities in EMEC and CMEC, for example, to discover applications. In examples, the interfaces may be referred to as Mpp-lfe and Mpp-cmec. Systems, methods, and/or instrumentalities for one or more of the following may be described herein: EMEC initiated discovery of one or more applications in CMEC, CMEC initiated registration with EMEC to announce availability of application(s), or CMEC initiated discovery of other CMEC application(s).

Abstract: Methods and apparatuses for discovery and selection of a Local Network Exposure Function (L-NEF) are described herein. A method of for registering with a Network Repository Function (NRF) performed by a L-NEF may include sending, to the NRF, a register registration message that includes a new NF network function (NF) profile, the new NF profile further including an identification of a Local Area Data Network (LADN), Service area information associated with the L-NEF, and a User Plane Function (UPF) Identifier (ID). The method may include receiving a registration response message from the NRF.

Abstract: The disclosure pertains to a method implemented in a Wireless Transmit/Receive Unit (WTRU) for service continuity during an application context relocation (ACR) procedure. The method includes determining, by the WTRU, one or more local area data network (LADN) data network names (DNNs) that require service continuity. The method additionally includes indicating, to a network by the WTRU, the LADN DNNs that require service continuity. The network is configured to use the list to maintain a protocol data unit (PDU) session toward a source LADN DNN, after the WTRU leaves a service area of a source LADN, while ACR is being executed and release the PDU session when the ACR is complete.

Abstract: Methods and apparatuses for privacy enhancement are provided herein. A method performed by a station, STA (201), may include transmitting, to an access point, AP (202), a first frame including information indicating that the STA (201) will use an over-the-air medium access control, otaMAC, address for a frame sent to the AP (202). The method may further include generating (210) a second frame for transmission to the AP (202) including a network MAC, nMAC, address of the STA (201), encrypting (211) the generated second frame, and replacing (212) the nMAC address with an otaMAC address either during the encryption or after the encryption. The method may further include transmitting (213) the encrypted second frame, including the otaMAC, to the AP (202), such that the AP (202) may replace (214) the otaMAC address with the nMAC address and decrypt (215) the second frame for forwarding via a distribution system, DS (203).

Abstract: Methods, apparatuses, and systems for enabling and configuring a time-sensitive networking (TSN) centralized network/distributed user model in a wireless communications system are provided. For example, a method for wireless communications includes receiving configuration information related to forwarding reservation information to a centralized network configuration (CNC) entity, receiving one or more user requests based on the received configuration information, determining reservation information from the received one or more user requests, and sending, based on the received configuration information, the reservation information to the CNC entity.

Abstract: Methods, apparatus, systems, architectures and interfaces for a wireless transmit receive unit (WTRU) performing a client-side edge resolution function (cERF) are provided. A method may include any of: transmitting, to a network-side edge application resolver (nEAR), a signal requesting an IP address identifying (e.g.

Abstract: A wireless transmit / receive unit, WTRU, connects to a first AP, receives domain identifiers, requests corresponding descriptors and receives a list of descriptors. An application on the WTRU requests a list of domains and attributes corresponding to service names or service sets, which is returned by the WTRU. The application selects one or more domains for communications, the WTRU selects corresponding network resources and the application connects to local services. After moving to a new location, the WTRU connects to a second AP and receives a second set of domain identifiers, selects the one matching the request from the application and provides these to the application that, with the aid of the WTRU connects to local services.

Abstract: Methods, apparatus, systems, architectures and interfaces for a wireless transmit receive unit (WTRU) performing a client-side edge resolution function (cERF) are provided. A method may include any of: determining a fully qualified domain name (FQDN) associated with a domain name server (DNS) request of an application associated with the WTRU; if the FQDN is associated with a valid edge instance (EI) record, selecting an EI for resolving the FQDN to an IP address; if the FQDN is not associated with a valid EI record: (1) transmitting a DNS query to a DNS server, (2) receiving an IP address associated with a selected EI to which the FQDN is resolved, and (3) updating the EI record with the IP address and the FQDN; and generating a traffic steering rule to re-direct uplink traffic associated with the application to the selected EI.

Abstract: Methods and apparatuses for reducing application instantiation delay and downtime are described herein. A method may comprise relocating an application function from a source Edge Data Network (EDN) component to a target EDN component. The method may comprise receiving an indication, and/or determining, based on at least one of a user mobility, resource optimization requirement, key performance indicator (KPI), or a failed relocation attempt, to relocate the application function. The method may further comprise performing a Protocol Data Unit (PDU) session establishment procedure toward the target EDN component. The method may further comprise determining, based on one or more received parameters for edge usage and capabilities, to relocate the application function. The method may further comprise sending, to a European Telecommunications Standards Institute (ETSI) Multi-access Edge Computing (MEC) orchestrator, an indication that the application function will be relocated.

Abstract: Method, apparatus, and systems for distribution of dynamic MAC addresses are provided. For example, a method implemented by a wireless transmit/receive unit (WTRU) for wireless communications includes receiving a message including port management information, determining configuration information from the port management information, where the configuration information indicates at least information related to a set of unicast or multicast addresses, and forwarding the configuration information to configure a Proxy using the information related to the set of unicast or multicast addresses.

Abstract: A method for setting up a multiple radio access technology (multi-RAT) device-to-device (D2D) communication is disclosed. An application function (AF) in a wireless transmit/receive unit (WTRU) may identify a group of multiple radio access technology (multi-RAT) capable WTRUs to a policy control function (PCF), wherein one or more multi-RAT capable WTRUs of the group of multi- RAT capable WTRUs register as having enhanced device-to-device (ED2D) functionality. The AF may select a multi-RAT capable WTRU from the group of multi-RAT capable WTRUs having ED2D functionality, as a relay for extended D2D operation. The device with ED2D function will act as Relay for ED2D (RED2D). The PCF may then reconfigure the RED2D with group related information. The RED2D may then configure D2D communication among the group of multi-RAT capable WTRUs.

Abstract: Methods, apparatus, systems, architectures and interfaces for a wireless transmit receive unit (WTRU) performing discovery of Edge Network Management (ENM) servers are provided. A method may include any of: transmitting any of a discover message, an inform message, and a request message including information indicating a request for discovery of ENM servers; receiving any of an offer message and an acknowledgement message including server information indicating any number of ENM servers associated with the request for discovery of ENM servers; and performing communications with any of the ENM servers for which there is received server information.

Abstract: As disclosed herein, there are one or more methods, systems, and/or devices relating to enhanced broadcast services and network optimization. In one example, a wireless network node may send a consumed service discovery request to a station (STA) via an access network query protocol (ANQP), wherein the STA is not associated with the network node. The network node may receive a consumed service discovery response including a set of service IDs and a B SSID of an access point (AP) for each service ID in the set of service IDs, wherein each service ID of the set of service IDs is a service consumed by the STA. In some cases, the consumed services are enhanced broadcast services (eBCS), the request is an ANQP query encapsulated in a GAS broadcast message, and/or request is an ANQP query encapsulated in a GAS groupcast message or a GAS unicast message.

Abstract: Service information (e.g., enhanced broadcast service (eBCS) information) may be distributed. Service (e.g., eBCS) capabilities may be advertised (e.g., by an access point (AP)), for example, by broadcasting a public action frame. A public action frame may include per-service information. A public action frame may be transmitted on a per service basis. A public action frame may combine authentication information and service information. Enhanced broadcast service origin authentication may be performed on a per service basis (e.g., using origin authentication information to authenticate broadcast data frames for a consumed service). Origin authentication information may be common to frames associated with different services. Services may be consumed without querying a service originating device. Stations (e.g., with and without association with an AP) may report consumption or usage of services, Reporting may be unsolicited or solicited (e.g., in response to a request from an AP).

Abstract: Methods, apparatus, systems, architectures and interfaces for a wireless transmit receive unit (WTRU) performing a client-side edge resolution function (cERF) are provided. A method may include any of: determining a fully qualified domain name (FQDN) associated with a domain name server (DNS) request of an application associated with the WTRU; if the FQDN is associated with a valid edge instance (EI) record, selecting an EI for resolving the FQDN to an IP address; if the FQDN is not associated with a valid EI record: (1) transmitting a DNS query to a DNS server, (2) receiving an IP address associated with a selected EI to which the FQDN is resolved, and (3) updating the EI record with the IP address and the FQDN; and generating a traffic steering rule to re-direct uplink traffic associated with the application to the selected EI.

Abstract: The application relates to various aspects for modeling software, preferably for use in wireless communication devices. One aspect relates to targeting a software model to a plurality of different operating systems/operating system combinations. Another aspect relates to abstracting the operating environment to an operating system/operating system combination. Another aspect relates to handling inter-processor communication. Another aspect relates to a common time manager.

Abstract: The invention relates to various aspects for modeling software, preferably for use in wireless communication devices. One aspect relates to targeting a software model to a plurality of different operating systems/operating system combinations. Another aspect relates to porting the software model to an operating environment common to all operating systems. Another aspect relates to abstracting the operating environment to an operating system/operating system combination. Another aspect relates to handling inter-processor communication. Another aspect relates to a common time manager. Another aspect relates to porting code developed using a single thread modeling tool to a multiple threaded environment. Another aspect relates to synchronizing groups of threads.