Patents by Inventor Robert Gentles

Robert Gentles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20070184024
    Abstract: The invention encompasses compounds of Formula I, pharmaceutically acceptable salts thereof, compositions, and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Application
    Filed: March 12, 2007
    Publication date: August 9, 2007
    Inventors: Nicholas Meanwell, Robert Gentles, Min Ding, John Bender, John Kadow, Piyasena Hewawasam, Thomas Hudyma, Xiaofan Zheng
  • Publication number: 20070078122
    Abstract: The invention encompasses compounds and salts of Formulas I, II, III, and IV as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Application
    Filed: September 6, 2006
    Publication date: April 5, 2007
    Inventors: Carl Bergstrom, John Bender, Robert Gentles, Piyasena Hewawasam, Thomas Hudyma, John Kadow, Scott Martin, Alicia Regueiro-Ren, Kap-Sun Yeung, Yong Tu, Katharine Grant-Young, Xiaofan Zheng
  • Publication number: 20070060565
    Abstract: The invention encompasses compounds of Formula I, pharmaceutically acceptable salts thereof, compositions, and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Application
    Filed: August 22, 2006
    Publication date: March 15, 2007
    Inventors: Nicholas Meanwell, Robert Gentles, Min Ding, John Bender, John Kadow, Piyasena Hewawasam, Thomas Hudyma, Xiaofan Zheng
  • Patent number: 7129247
    Abstract: The present invention relates to novel heterocyclyl-containing diaryl sulfide compounds that are useful for treating inflammatory and immune diseases, to pharmaceutical compositions comprising these compounds, and to methods of inhibiting inflammation or suppressing immune response in a mammal.
    Type: Grant
    Filed: February 9, 2004
    Date of Patent: October 31, 2006
    Assignee: Abbott Laboratories
    Inventors: Gary T. Wang, Sheldon Wang, Robert Gentles
  • Publication number: 20060166964
    Abstract: Indole compounds of Formula I are described. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV. Different forms and compositions comprising the compounds are also described as well as methods of preparing the compounds.
    Type: Application
    Filed: February 3, 2006
    Publication date: July 27, 2006
    Inventors: Thomas Hudyma, Xiaofan Zheng, Feng He, Min Ding, Carl Bergstrom, Piyasena Hewawasam, Scott Martin, Robert Gentles
  • Publication number: 20060046983
    Abstract: Indole compounds of Formula I are described. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV. Different forms and compositions comprising the compounds are also described as well as methods of preparing the compounds.
    Type: Application
    Filed: July 14, 2005
    Publication date: March 2, 2006
    Inventors: Thomas Hudyma, Xiaofan Zheng, Feng He, Min Ding, Carl Bergstrom, Piyasena Hewawasam, Scott Martin, Robert Gentles
  • Publication number: 20050014746
    Abstract: The present invention relates to novel heterocyclyl-containing diaryl sulfide compounds that are useful for treating inflammatory and immune diseases, to pharmaceutical compositions comprising these compounds, and to methods of inhibiting inflammation or suppressing immune response in a mammal.
    Type: Application
    Filed: February 9, 2004
    Publication date: January 20, 2005
    Inventors: Gary Wang, Sheldon Wang, Robert Gentles
  • Patent number: 6787542
    Abstract: The present invention relates to novel heterocyclyl-containing diaryl sulfide compounds that are useful for treating inflammatory and immune diseases, to pharmaceutical compositions comprising these compounds, and to methods of inhibiting inflammation or suppressing immune response in a mammal.
    Type: Grant
    Filed: June 25, 2001
    Date of Patent: September 7, 2004
    Assignee: ICOS Corporation
    Inventors: Gary T. Wang, Sheldon Wang, Robert Gentles
  • Publication number: 20020132807
    Abstract: The present invention relates to novel heterocyclyl-containing diaryl sulfide compounds that are useful for treating inflammatory and immune diseases, to pharmaceutical compositions comprising these compounds, and to methods of inhibiting inflammation or suppressing immune response in a mammal.
    Type: Application
    Filed: June 25, 2001
    Publication date: September 19, 2002
    Inventors: Gary T. Wang, Sheldon Wang, Robert Gentles
  • Patent number: 5327771
    Abstract: A loading probe for use in testing transducers includes an elongated body capable of simulating the normal acoustic impedance presented to a transducer to be tested by the medium in which the transducer is to operate. The main body of the loading probe has a tube made from a rigid material, and a rod having an elongated convergent portion extending into the interior of the tube so as to define a cavity which has a varying cross section. The cavity houses a core of material having a close match of acoustic impedance with the material of the tube and rod but a higher acoustic loss factor. The cavity is sealed. The active end of the loading probe carries a piezoelectric element having a planar form, and a protective end cap is bonded to the active end of the loading probe to enclose the piezoelectric element.
    Type: Grant
    Filed: June 25, 1992
    Date of Patent: July 12, 1994
    Assignee: GEC Ferranti Defence Systems Limited
    Inventor: Robert Gentles
  • Patent number: 4959992
    Abstract: An acoustic loading rod for use in testing transducers which are intended for use in a liquid medium. The rod comprises an elongated body (10) capable of simulating the normal acoustic impedance presented to a transducer to be tested by the medium in which the transducer is to operate, the rod (10) having a bore (30) in its main body portion containing a core of material having a close match of acoustic impedance with the material of the rod but a higher acoustic loss factor. Active piezo-electric transducer (22) is mounted between the ends of the rod.
    Type: Grant
    Filed: April 17, 1989
    Date of Patent: October 2, 1990
    Assignee: The Marconi Company Limited
    Inventor: Robert Gentles