Patents by Inventor ROBERT GERSTMEIR

ROBERT GERSTMEIR has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing L-leucine, L-valine, L-isoleucine, ?-ketoisovalerate, ?-keto-beta-methylvalerate, or ?-ketoisocaproate using recombinant Corynebacteria that contain the ilvBN operon which can be induced by propionate
    Patent number: 10113190
    Abstract: The invention relates to a process for the production of amino acids and keto acids using microorganisms, in which a promoter inducible by propionate makes possible the regulated expression of certain genes.
    Type: Grant
    Filed: May 23, 2014
    Date of Patent: October 30, 2018
    Assignee: Evonik Degussa GmbH
    Inventors: Robert Gerstmeir, Hugo Ramos-Vera, Kay Marin
  • Method for the preparation of 2-keto carboxylic acid
    Patent number: 9879289
    Abstract: The present invention refers to a method for the preparation of 2-keto carboxylic acid having the general formula R1—CO—COOH, wherein R1 is a branched alkyl group having 3 to 7 carbon atoms, or a salt thereof, comprising a fermentation step wherein a microorganism is grown in a culture medium in order to provide a culture broth containing 2-keto carboxylic acid or a salt thereof.
    Type: Grant
    Filed: May 10, 2010
    Date of Patent: January 30, 2018
    Assignee: Evonik Degussa GmbH
    Inventors: Andreas Karau, Nicolas Morin, Robert Gerstmeir
  • Feedback-resistant alpha-isopropylmalate synthases
    Patent number: 9347048
    Abstract: The invention relates to an isolated nucleotide sequence encoding an amino acid sequence that is at least ?90%, ?92%, ?94%, ?96%, ?97%, ?98%, ?99% or 100%, preferably ?97%, particularly preferably ?98%, very particularly preferably ?99%, and extremely preferably 0%, identical to the amino acid sequence of SEQ ID NO:2, wherein SEQ ID NO:2, at position 553, or at a corresponding position of the amino acid sequence, has a proteinogenic amino acid other than L-tyrosine, to a microorganism comprising the nucleotide sequence and also to a process for producing fine chemicals using this microorganism.
    Type: Grant
    Filed: April 12, 2013
    Date of Patent: May 24, 2016
    Assignee: Evonik Technochemie GmbH
    Inventors: Robert Gerstmeir, Iris Wiegrabe
  • METHOD FOR PRODUCING L-LEUCINE, L-VALINE, L-ISOLEUCINE, ALPHA-KETOISOVALERATE, ALPHA-KETO-BETA-METHYLVALERATE, OR ALPHA-KETOISOCAPROATE USING RECOMBINANT CORYNEBACTERIA THAT CONTAIN THE ILVBN OPERON WHICH CAN BE INDUCED BY PROPIONATE
    Publication number: 20160115506
    Abstract: The invention relates to a process for the production of amino acids and keto acids using microorganisms, in which a promoter inducible by propionate makes possible the regulated expression of certain genes.
    Type: Application
    Filed: May 23, 2014
    Publication date: April 28, 2016
    Applicant: Evonik Degussa GmbH
    Inventors: Robert Gerstmeir, Hugo Ramos-Vera, Kay Marin
  • FEEDBACK-RESISTANT ALPHA-ISOPROPYLMALATE SYNTHASES
    Publication number: 20150079641
    Abstract: The invention relates to an isolated nucleotide sequence encoding an amino acid sequence that is at least ?90%, ?92%, ?94%, ?96%, ?97%, ?98%, ?99% or 100%, preferably ?97%, particularly preferably ?98%, very particularly preferably ?99%, and extremely preferably 0%, identical to the amino acid sequence of SEQ ID NO:2, wherein SEQ ID NO:2, at position 553, or at a corresponding position of the amino acid sequence, has a proteinogenic amino acid other than L-tyrosine, to a microorganism comprising the nucleotide sequence and also to a process for producing fine chemicals using this microorganism.
    Type: Application
    Filed: April 12, 2013
    Publication date: March 19, 2015
    Applicant: EVONIK INDUSTRIES AG
    Inventors: Robert Gerstmeir, Iris Wiegrabe
  • Process for the fermentative preparation of L-ornithine
    Patent number: 8951759
    Abstract: A process for the fermentative preparation of L-ornithine using microorganisms characterized by an increased export of the amino acid.
    Type: Grant
    Filed: February 20, 2014
    Date of Patent: February 10, 2015
    Assignee: Evonik Degussa GmbH
    Inventors: Wilfried Claes, Robert Gerstmeir
  • PROCESS FOR THE FERMENTATIVE PREPARATION OF L-ORNITHINE
    Publication number: 20140206068
    Abstract: A process for the fermentative preparation of L-ornithine using microorganisms characterized by an increased export of the amino acid.
    Type: Application
    Filed: February 20, 2014
    Publication date: July 24, 2014
    Applicant: Evonik Degussa GmbH
    Inventors: Wilfried CLAES, Robert Gerstmeir
  • Process for the fermentative preparation of L-ornithine
    Patent number: 8741608
    Abstract: A process for the fermentative preparation of L-ornithine using microorganisms characterized by an increased export of the amino acid.
    Type: Grant
    Filed: March 29, 2011
    Date of Patent: June 3, 2014
    Assignee: Evonik Degussa GmbH
    Inventors: Wilfried Claes, Robert Gerstmeir
  • METHOD FOR THE PREPARATION OF 2-KETO CARBOXYLIC ACID
    Publication number: 20120065428
    Abstract: The present invention refers to a method for the preparation of 2-keto carboxylic acid having the general formula R1—CO—COOH, wherein R1 is a branched alkyl group having 3 to 7 carbon atoms, or a salt thereof, comprising a fermentation step wherein a microorganism is grown in a culture medium in order to provide a culture broth containing 2-keto carboxylic acid or a salt thereof.
    Type: Application
    Filed: May 10, 2010
    Publication date: March 15, 2012
    Applicant: Evonik Degussa GmbH
    Inventors: Andreas Karau, Nicolas Morin, Robert Gerstmeir
  • PROCESS FOR THE FERMENTATIVE PREPARATION OF L -ORNITHINE
    Publication number: 20110244529
    Abstract: A process for the fermentative preparation of L-ornithine using microorganisms characterized by an increased export of the amino acid.
    Type: Application
    Filed: March 29, 2011
    Publication date: October 6, 2011
    Applicant: EVONIK DEGUSSA GMBH
    Inventors: WILFRIED CLAES, ROBERT GERSTMEIR