Patents by Inventor Robert Gerszten

Robert Gerszten has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antidotes to cyanide poisoning
    Patent number: 11484521
    Abstract: The present application provides, inter alia, a compound of Formula (I): or a pharmaceutically acceptable salt thereof, and methods of use of the compound of Formula (I) for treatment and prevention of cyanide poisoning.
    Type: Grant
    Filed: April 12, 2018
    Date of Patent: November 1, 2022
    Assignees: The General Hospital Corporation, The Regents of the University of California
    Inventors: Randall Peterson, Robert Gerszten, Anjali Nath, Calum MacRae, Gerry Boss, Matt Brenner, Sari Brenner Mahon
  • Antidotes to Cyanide Poisoning
    Publication number: 20220105066
    Abstract: The present application provides, inter alia, a compound of Formula (I): or a pharmaceutically acceptable salt thereof, and methods of use of the compound of Formula (I) for treatment and prevention of cyanide poisoning.
    Type: Application
    Filed: October 14, 2021
    Publication date: April 7, 2022
    Inventors: Randall Peterson, Robert Gerszten, Anjali Nath, Calum MacRae, Gerry Boss, Matt Brenner, Sari Brenner Mahon
  • Antidotes to Cyanide Poisoning
    Publication number: 20200276148
    Abstract: The present application provides, inter alia, a compound of Formula (I): or a pharmaceutically acceptable salt thereof, and methods of use of the compound of Formula (I) for treatment and prevention of cyanide poisoning.
    Type: Application
    Filed: April 12, 2018
    Publication date: September 3, 2020
    Inventors: Randall Peterson, Robert Gerszten, Anjali Nath, Calum MacRae, Gerry Boss, Matt Brenner, Sari Brenner Mahon
  • 2-AAA as a Biomarker and Therapeutic Agent for Diabetes
    Publication number: 20160030373
    Abstract: Methods for treating a glucose-related metabolic disorder (e.g., diabetes) comprising administration of 2-aminoadipic acid (2-AAA) to subjects in need thereof. Also described are methods for predicting a subject's risk of developing a glucose-related metabolic disorder, and to methods for selecting and monitoring a treatment for a glucose-related metabolic disorder (e.g., diabetes).
    Type: Application
    Filed: March 10, 2014
    Publication date: February 4, 2016
    Inventors: Robert Gerszten, Thomas Wang, Clary Clish
  • Novel Biomarkers For Cardiovascular Injury
    Publication number: 20140045714
    Abstract: The invention provides methods for the early detection of cardiovascular injury using one or more cardiac injury biomarkers identified herein.
    Type: Application
    Filed: October 26, 2011
    Publication date: February 13, 2014
    Inventors: Robert Gerszten, Michael Fifer, Steven A. Carr
  • Lipidomic Biomarkers of Diabetes
    Publication number: 20120214821
    Abstract: The invention, in some aspects, relates to methods for predicting a subject's risk of developing a glucose-related metabolic disorder, e.g., diabetes. In some aspects, the invention relates to methods for selecting and monitoring a treatment for a glucose-related metabolic disorder, e.g., diabetes.
    Type: Application
    Filed: January 20, 2012
    Publication date: August 23, 2012
    Applicants: THE BROAD INSTITUTE, INC., THE GENERAL HOSPITAL CORPORATION
    Inventors: Robert Gerszten, Thomas Wang, Eugene Rhee, Clary Clish
  • MULTIPLEXED BIOMARKERS OF INSULIN RESISTANCE
    Publication number: 20110311650
    Abstract: The invention, in some aspects, relates to methods for characterizing glucose-related metabolic disorders. In some aspects, the invention relates to methods and kits useful for diagnosing, classifying, profiling, and treating glucose-related metabolic disorders. In some aspects, the invention relates to methods useful for diagnosing, classifying, profiling, and treating diabetes.
    Type: Application
    Filed: July 7, 2009
    Publication date: December 22, 2011
    Inventors: Thomas Wang, Oded Shaham, Robert Gerszten, Vamsi K. Mootha, Vasan S. Ramachandran, Martin Larson
  • METHODS OF DETECTING AND TREATING MYOCARDIAL ISCHEMIA AND MYOCARDIAL INFARCTION
    Publication number: 20090269796
    Abstract: Methods of detecting and treating myocardial ischemia and myocardial infarction based on the differential expression of metabolic products are described herein.
    Type: Application
    Filed: November 25, 2008
    Publication date: October 29, 2009
    Applicant: THE GENERAL HOSPITAL CORPORATION
    Inventors: Robert Gerszten, Marc S. Sabatine, Michael A. Fifer
  • Methods of Detecting Myocardial Ischemia and Myocardial Infarction
    Publication number: 20080261317
    Abstract: The disclosed methods address the identification of myocardial ischemia and myocardial infarction using metabolomics, as well as the identification of metabolic products whose differential expression over time is indicative of myocardial ischemia and/or myocardial infarction.
    Type: Application
    Filed: September 6, 2005
    Publication date: October 23, 2008
    Inventors: Michael A. Fifer, Marc S. Sabatine, Robert Gerszten