Abstract: Disclosed are compounds, compositions and methods related PPAR antagonists. Certain compounds are effective at inhibiting PPARs. The compositions can be used to inhibit PPARs, treat cancer and treat metabolic disorders.

Abstract: The invention relates to pharmaceutical compositions and a method of preventing or reducing the incidence of AF and thereby reducing the risk of morbidity and mortality in patients having symptomatic heart failure comprising administering to such patient an effective amount of valsartan, or pharmaceutically acceptable salts thereof, alone or in combination with another therapeutic agent, optionally in the presence of a pharmaceutically acceptable carrier.

Abstract: The invention provides systems and methods that allow retail entities to let consumers register a product or warranty at the point of sale. More specifically, the systems and methods described herein allow a retailer to identify a point during a purchasing transaction wherein the consumer has completed a transaction. At that time, the retailer may presented to the consumer an interface that the consumer may easily complete to allow the consumer to participate in a product or warned she registration process. As such, the systems and methods described here and make the product registration process part of the purchase transaction and therefore make the product registration process seamless and more facile. Consequently it is understood that consumer participation within the product registration process increases.