Abstract: A trailer mountable portable ladder assembly includes a base plate having an upper surface and a lower surface. A post is attached to and extends downwardly from the lower surface and is sized to be removably extended into a stake pocket. A fastening member is mechanically mounted in the post. The fastening member is actuated to frictionally engage an inner surface of the stake pocket to releasably retain the post in the stake pocket. A ladder is attached to the base plate.

Abstract: The present invention is directed to an improved process for producing substantially pure fluorescein, as well as to substantially pure fluorescein compositions prepared by the process. The invention is particularly directed to the provision of pharmaceutical compositions for use in angiography. The substantially pure fluorescein produced by the process of the present invention is low in color, low in sodium chloride content, and substantially free of pyridine.

Abstract: The present invention is directed to an improved process for producing substantially pure fluorescein, as well as to substantially pure fluorescein compositions prepared by the process. The invention is particularly directed to the provision of pharmaceutical compositions for use in angiography. The substantially pure fluorescein produced by the process of the present invention is low in color, low in sodium chloride content, and substantially free of pyridine.

Abstract: Octahydro-pyrrolo[3,4-b]pyrrole derivatives are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands, Octahydro-pyrrolo[3,4-b]pyrrole compounds, methods for using such compounds, compositions for making them, and processes for preparing such compounds are disclosed herein.

Abstract: The present invention relates to the use of selective P2X7 receptor antagonists of formula I, or a pharmaceutically acceptable salt or prodrug thereof wherein D, R1 and R2 are as defined in claim 1, for the treatment of neuropathic pain, chronic inflammatory pain, inflammation, neurodegeneration and for promoting neuroregeneration,

Abstract: A wing having a transition region forming a blended, aerodynamic transition between inner and outer regions of the wing. The blended transition region does not include any planform breaks at the leading and trailing edges, where conventional wings would have such planform breaks. This allows the wing to be manufactured without significant forming and/or shot-peening operations to conform the skin of the wing to the planform breaks. Thus, the wing of the present invention can be manufactured with less cost and in less time, and provide even better aerodynamics than conventional aircraft wings. The wing of the present invention is further suitable for use on aircraft or aerospace vehicles, or any airborne vehicle requiring one or more aerodynamic airfoils or wing-like structures.

Abstract: Compounds of the present invention modulate PN3 in mammals and are useful in treating pain in mammals.

Abstract: A mobile platform lift increasing system includes at least one wing-shaped structure having a leading edge, a trailing edge and a chord length perpendicularly measurable between the leading and trailing edges. A rotatable control surface is located near a trailing edge undersurface. The control surface length is approximately one to five percent of the chord length. A deployment device is positioned between the wing shaped structure and the control surface. The deployment device operably rotates the control surface through a plurality of positions ranging between an initial position and a fully deployed position. Wing lift is increased at speeds up to approximately transonic speed by continuously rotating the control surface to accommodate variables including mobile platform weight change from fuel usage.

Abstract: In a replicated component system, changing the condition of a component can deleteriously effect the system as a whole unless the result of making such a change may have on other components is considered. In response to a request to change the condition of a subject component to a specified condition, where the request is from a fixed set of request operations, the request is first validated using a particular validation algorithm associated with the request type. If the request is successfully validated (i.e., a determination is made using the validation algorithm that making the requested change will not negatively affect the system or components with which the subject component has a relationship), then the request is realized using a particular realization algorithm associated with the request type. Each validation algorithm and realization algorithm are from fixed sets of such algorithms that are associated with each possible request operation.

Abstract: In a replicated component system, changing the condition of a component can deleteriously affect the system as a whole unless the result of making such a change may have on other components is considered. In response to a request to change the condition of a subject component to a specified condition, the request is first validated using a particular validation algorithm associated with the request type. Prior to effecting a change to any component in the system, the configuration controller is provided with information that includes the type of component that each component in the system is and the relationships that exist between components. This information is provided through a graphical user interface in which the attributes of each component type and the relationships between components are specified using dialog windows and a canvas window which visually displays representations of each component in the system and the relationships that exist between these components.

Abstract: The present invention is a thermoelectric device and method designed to create a martensitic state in a shape memory alloy. The invention allows for prolonged use without overheating, and is more less expensive and easier to use than current art. The device is comprised of a cooling tip that is made of a thermally conductive material in contact with the thermoelectric module powered by an external DC converter. A heat sink is in thermal contact with the heating face of the module with cooling fins to draw heat away from the module. A continuous supply of cooling gas or liquid flows over the cooling fins or liquid channels to further cool the module. The DC power supply is controlled by a pneumatic device that will only operate under positive gas pressure, thus ensuring proper cooling of the heat sink of the invention. The cooling tip extends from the front end of an insulating body, the body having a threaded chucking hold for easy removal and changeout of the cooling tip.