Patents by Inventor Robert H. Baloh

Robert H. Baloh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sequences associated with TDP-43 proteinopathies and methods of using the same
    Patent number: 10683544
    Abstract: The present invention provides nucleic acids and peptides, and methods of using the nucleic acids and peptides to identify subjects at risk for a TDP-43 proteinopathy. The invention also provides for an array comprising the nucleic acids and peptides of the invention.
    Type: Grant
    Filed: November 8, 2016
    Date of Patent: June 16, 2020
    Assignee: Washington University
    Inventors: Nigel J. Cairns, Robert H. Baloh, Alan Pestronk, Michael A. Gitcho, Alison M. Goate
  • SEQUENCES ASSOCIATED WITH TDP-43 PROTEINOPATHIES AND METHODS OF USING THE SAME
    Publication number: 20170067112
    Abstract: The present invention provides nucleic acids and peptides, and methods of using the nucleic acids and peptides to identify subjects at risk for a TDP-43 proteinopathy. The invention also provides for an array comprising the nucleic acids and peptides of the invention.
    Type: Application
    Filed: November 8, 2016
    Publication date: March 9, 2017
    Inventors: Nigel J. Cairns, Robert H. Baloh, Alan Pestronk, Michael A. Gitcho, Alison M. Goate
  • Sequences associated with TDP-43 proteinopathies and methods of using the same
    Patent number: 9523128
    Abstract: The present invention provides nucleic acids and peptides, and methods of using the nucleic acids and peptides to identify subjects at risk for a TDP-43 proteinopathy. The invention also provides for an array comprising the nucleic acids and peptides of the invention.
    Type: Grant
    Filed: October 14, 2014
    Date of Patent: December 20, 2016
    Assignee: WASHINGTON UNIVERSITY
    Inventors: Nigel J. Cairns, Robert H. Baloh, Alan Pestronk, Michael A. Gitcho, Alison M. Goate
  • SEQUENCES ASSOCIATED WITH TDP-43 PROTEINOPATHIES AND METHODS OF USING THE SAME
    Publication number: 20150065384
    Abstract: The present invention provides nucleic acids and peptides, and methods of using the nucleic acids and peptides to identify subjects at risk for a TDP-43 proteinopathy. The invention also provides for an array comprising the nucleic acids and peptides of the invention.
    Type: Application
    Filed: October 14, 2014
    Publication date: March 5, 2015
    Inventors: Nigel J. Cairns, Robert H. Baloh, Alan Pestronk, Michael A. Gitcho, Alison M. Goate
  • Sequences associated with TDP-43 proteinopathies and methods of using the same
    Patent number: 8889597
    Abstract: The present invention provides nucleic acids and peptides, and methods of using the nucleic acids and peptides to identify subjects at risk for a TDP-43 proteinopathy. The invention also provides for an army comprising the nucleic acids and peptides of the invention.
    Type: Grant
    Filed: January 30, 2009
    Date of Patent: November 18, 2014
    Assignee: Washington University
    Inventors: Nigel J. Cairns, Robert H Baloh, Alan Pestronk, Michael A. Gitcho, Alison M. Goate
  • SEQUENCES ASSOCIATED WITH TDP-43 PROTEINOPATHIES AND METHODS OF USING THE SAME
    Publication number: 20110065600
    Abstract: Nucleic acids and peptides and methods of using thereof to identify subjects at risk for a TDP-43 proteinopathy are disclosed An array is also disclosed which contains the nucleic acids and peptides
    Type: Application
    Filed: January 30, 2009
    Publication date: March 17, 2011
    Applicant: THE WASHINGTON UNIVERSITY
    Inventors: Niegel J. Cairns, Robert H Baloh, Alan Pestronk, Michael A. Gitcho, Alison M. Goate
  • GFR?1-RET specific agonists and methods therefor
    Patent number: 6866851
    Abstract: Chimeric GDNF family ligands which activate a GFR?/RET are disclosed. Included are chimeras which activate GFR?1/RET but do not activate GFR?2-RET or GFR?3-RET. The chimeras are useful in providing trophic support to a mammalian cell or in producing differentiation of a mammalian cell, or both, particularly when the cell is in a patient suffering from various diseases, in particular Parkinson's Disease.
    Type: Grant
    Filed: December 28, 1999
    Date of Patent: March 15, 2005
    Assignee: Washington University
    Inventors: Jeffrey D. Milbrandt, Robert H. Baloh
  • ARTEMIN, A NEUROTROPHIC FACTOR
    Publication number: 20020002269
    Abstract: A novel growth factor, artemin, which belongs to the GDNF/neurturin/persephin family of growth factors, is disclosed. The human and mouse amino sequences have been identified. Human and mouse artemin genomic DNA sequences have been cloned and sequenced and the respective cDNA sequences identified. In addition, methods for treating degenerative conditions using artemin, methods for detecting artemin gene alterations and methods for detecting and monitoring patient levels of artemin are provided.
    Type: Application
    Filed: December 24, 1998
    Publication date: January 3, 2002
    Inventors: JEFFREY D. MILBRANDT, ROBERT H. BALOH
  • Artemin, a novel neurotrophic factor
    Patent number: 6284540
    Abstract: A novel growth factor, artemin, which belongs to the GDNF/neurturin/persephin family of growth factors, is disclosed. The human and mouse amino sequences have been identified. Human and mouse artemin genomic DNA sequences have been cloned and sequenced and the respective cDNA sequences identified. In addition, methods for treating degenerative conditions using artemin, methods for detecting artemin gene alterations and methods for detecting and monitoring patient levels of artemin are provided.
    Type: Grant
    Filed: December 24, 1998
    Date of Patent: September 4, 2001
    Assignee: Washington University
    Inventors: Jeffrey D. Milbrandt, Robert H. Baloh