Patents by Inventor Robert H. Barker

Robert H. Barker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • UDP glycosyltransferase inhibitors and methods of use
    Patent number: 11098056
    Abstract: Described herein is a compound of Formula (I), and pharmaceutically acceptable salts thereof. Also described herein are compositions and the use of such compositions in methods of treating a variety of diseases and conditions, in particular Krabbe's Disease (KD) and Metachromatic leukodystrophy (MLD).
    Type: Grant
    Filed: October 1, 2019
    Date of Patent: August 24, 2021
    Assignee: GENZYME CORPORATION
    Inventors: Sungtaek Lim, Robert H. Barker, Jr., Mary A. Cromwell, Elina Makino, Bradford Hirth, John Jiang, Sachin Maniar, Mark Munson, Yong-Mi Choi, Sukanthini Thurairatnam, Kwon Yon Musick, James Pribish, Michael Angelastro
  • UDP GLYCOSYLTRANSFERASE INHIBITORS AND METHODS OF USE
    Publication number: 20200102324
    Abstract: Described herein is a compound of Formula (I), and pharmaceutically acceptable salts thereof. Also described herein are compositions and the use of such compositions in methods of treating a variety of diseases and conditions, in particular Krabbe's Disease (KD) and Metachromatic leukodystrophy (MLD).
    Type: Application
    Filed: October 1, 2019
    Publication date: April 2, 2020
    Inventors: Sungtaek LIM, Robert H. BARKER, JR., Mary A. CROMWELL, Elina MAKINO, Bradford HIRTH, John JIANG, Sachin MANIAR, Mark MUNSON, Yong-Mi CHOI, Sukanthini THURAIRATNAM, Kwon Yon MUSICK, James PRIBISH, Michael ANGELASTRO
  • Anionic polymers as species specific antibacterial agents
    Patent number: 6730295
    Abstract: The present invention relates to the discovery that certain anionic polymers have useful antibacterial activity.
    Type: Grant
    Filed: May 1, 2001
    Date of Patent: May 4, 2004
    Assignee: Genzyme Corporation
    Inventors: Richard J. Fitzpatrick, Robert H. Barker, Jr.
  • Ionene polymers and their use in treating mucositis
    Publication number: 20030021761
    Abstract: A method of using ionene polymers for the treatment of mucositis and oral mucositis in mammals is provided. The method comprises administering to a mammal an effective amount of an ionene polymer to prophylactically or therapeutically treat mucositis.
    Type: Application
    Filed: January 17, 2002
    Publication date: January 30, 2003
    Applicant: GelTex Pharmaceuticals, Inc.
    Inventors: Richard J. Fitzpatrick, Philip J. Goddard, Robert H. Barker, Keith K. Shackett, Jeffrey D. Klinger
  • Oligonucleotide mediated reversal of drug resistance
    Patent number: 6440660
    Abstract: The present invention provides methods of resensitizing an anti-drug-resistant infectious agent to a drug. Also disclosed are synthetic oligonucleotides having a nucleotide sequence complementary to a region of pfmdr1 nucleic acid, and methods of down-regulating the expression of pfmdr nucleic acid using such oligonucleotides.
    Type: Grant
    Filed: November 12, 1996
    Date of Patent: August 27, 2002
    Assignees: Hybridon, Inc., Worchester Foundation for Biomedical Research
    Inventors: Robert H. Barker, Jr., Eliezer Rapaport, Paul C. Zamecnik
  • Anionic polymers as species specific antibacterial agents
    Publication number: 20020034491
    Abstract: The present invention relates to the discovery that certain anionic polymers have useful antibacterial activity.
    Type: Application
    Filed: May 1, 2001
    Publication date: March 21, 2002
    Applicant: GelTex Pharmaceuticals, Inc.
    Inventors: Richard J. Fitzpatrick, Robert H. Barker
  • Solubilization of protein with ethanol-acetonitril-water solvent system
    Patent number: 3975343
    Abstract: A solvent system composed of ethanol-acetonitrile-water dissolved certain membrane proteins of biological origin. The solvent system was optically transparent to ultraviolet radiation from 200 to 400 nanometers (nm). This transparency permitted ascertainment of spectral characteristics of membrane proteins at these wavelengths.
    Type: Grant
    Filed: June 27, 1975
    Date of Patent: August 17, 1976
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: Thomas J. Jacks, Robert H. Barker, Thomas P. Hensarling