Abstract: Apelin receptor modulators can improve physical performance, slow progression of age-related frailty, and can reduce age-related muscle weakness in human patients. This disclosure provides methods for treating muscle conditions using a particular class of apelin receptor modulators (e.g., agonists). The muscle condition can be an age-related muscle condition. Also provided is a method for maintaining and/or increasing muscle mass, muscle function, and/or muscle strength in an elderly subject by administration of the apelin receptor modulator. In some embodiments, the apelin receptor modulator (e.g., agonist) is BGE-105, or a pharmaceutically acceptable salt thereof.

Abstract: The wear sleeve in the present invention comprises a rearward split ring portion and an intermediate cylindrical ring portion adjacent a forward shoulder portion. The outer diameter of the wear sleeve intermediate portion and rearward split ring portion is uniform. The wear sleeve is inserted into the bit holder's stepped bore aperture. The split ring portion is radially compressed by the smaller diameter opposite portion end as the sleeve is hammered and axially displaced into the bit holder. The split ring portion forms frictional contact with the opposite end portion of the aperture. The wear sleeve friction fit can be easily removed manually in the field. The bit holder and cooperating support block are designed to limit the amount of relative yaw between the two members during operation to reduce the overall wear there between.

Abstract: The wear sleeve in the present cutter tool assembly comprises a rearward split ring portion and an intermediate cylindrical ring portion adjacent a forward shoulder portion. The outer diameter of the wear sleeve intermediate portion and rearward split ring portion is uniform. The wear sleeve is inserted into the bit holder's stepped bore aperture. The split ring portion is radially compressed by the smaller diameter rearward end as the sleeve is hammered and axially displaced into the bit holder. The split ring portion forms frictional contact with the opposite end portion of the aperture. The wear sleeve friction fit can be easily removed manually in the field. The bit holder and cooperating support block are designed to limit the amount of relative yaw between the two members during operation to reduce the overall wear there between.

Abstract: Using intelligent network processing, call notification allows a subscriber to determine the name and telephone number of one or more numbers of recent parties to call the subscriber. An incoming call to the subscriber's number activates a terminating attempt type trigger in the central office serving the subscriber. The trigger causes communication between that office and a service control point (SCP). Under instructions from the SCP, the central office indicates a disposition event regarding the call, e.g., whether the line was busy or there was no answer. If the subscriber's line is busy or does not answer, the SCP records at least the telephone number of the caller and the time and date of the call. Later, the subscriber dials a feature code, and the SCP instructs the central office to route the call to an intelligent peripheral (IP).

Abstract: A cutting tool assembly including a protective wear sleeve that is fixed in the cavity of a bit holder by a tapered wedge portion that is compressed in a correspondingly tapered portion of the bit holder cavity and an accompanying retainer both combine affix the wear sleeve to the bit holder cavity in a secure manner. The applicant's protective wear sleeve invention can be set in the bit holder by several axial blows with a hammer or other appropriate tool. Unlike some other designs in the prior art which require the insertion of a pin or nut threaded onto a bolt or clip connected to the rear end of the cutting to secure the wear protection sleeve to the bit holder in the invention no other assembly step is necessary to secure the protective sleeve inside the bit holder cavity. The protective sleeve will remain in this position with no relative axial movement or rotation between the wear sleeve and the bit holder during operation of the cutting tool machinery.

Abstract: The wear sleeve in the present invention comprises a rearward split ring portion and an intermediate cylindrical ring portion adjacent a forward shoulder portion. The outer diameter of the wear sleeve intermediate portion and rearward split ring portion is uniform. The wear sleeve is inserted into the bit holder's stepped bore aperture. The split ring portion is radially compressed by the smaller diameter opposite portion end as the sleeve is hammered and axially displaced into the bit holder. The split ring portion forms frictional contact with the opposite end portion of the aperture. The wear sleeve friction fit can be easily removed manually in the field. The bit holder and cooperating support block are designed to limit the amount of relative yaw between the two members during operation to reduce the overall wear there between.

Abstract: The wear sleeve in the present invention comprises a rearward split ring portion and an intermediate cylindrical ring portion adjacent a forward shoulder portion. The outer diameter of the wear sleeve intermediate portion and rearward split ring portion is uniform. The wear sleeve is inserted into the bit holder's stepped bore aperture. The split ring portion is radially compressed by the smaller diameter opposite portion end as the sleeve is hammered and axially displaced into the bit holder. The split ring portion forms frictional contact with the opposite end portion of the aperture. The wear sleeve friction fit can be easily removed manually in the field. The bit holder and cooperating support block are designed to limit the amount of relative yaw between the two members during operation to reduce the overall wear there between.

Abstract: A cutting tool assembly including a protective wear sleeve that is fixed in the cavity of a bit holder by a tapered wedge portion that is compressed in a correspondingly tapered portion of the bit holder cavity and an accompanying retainer both combine affix the wear sleeve to the bit holder cavity in a secure manner. The applicant's protective wear sleeve invention can be set in the bit holder by several axial blows with a hammer or other appropriate tool. Unlike some other designs in the prior art which require the insertion of a pin or nut threaded onto a bolt or clip connected to the rear end of the cutting to secure the wear protection sleeve to the bit holder in the invention no other assembly step is necessary to secure the protective sleeve inside the bit holder cavity. The protective sleeve will remain in this position with no relative axial movement or rotation between the wear sleeve and the bit holder during operation of the cutting tool machinery.

Abstract: An excavation cutting tool holder includes a cutting tool holder having a holder body portion and a holder shank, the holder shank having a press fit portion and a shank bottom end, the shank press fit portion having a shank press fit dimension and the shank bottom end having a tool holder locator. The excavation cutting tool holder assembly further includes a support block having a block body, the block body having a block bore, the block bore having a block bore press fit portion and a block engagor, the block bore press fit portion having a block bore press fit dimension less than the shank press fit dimension such that the shank press fit portion press fits with the block bore press fit portion while the block engagor engages the tool holder locator so as to orient the cutting tool holder relative to the support block.

Abstract: A cutting bit has a bit body which has a forward end and a rearward end. The bit body contains a seat at the forward end thereof. The bit body contains a bore intersecting the seat wherein a bore wall defines the bore. A cutting insert is received by the seat wherein the cutting insert presents a side surface facing the bore. A wedge has a generally longitudinal seating surface. The wedge has a support surface opposite to the longitudinal seating surface. The wedge is received within the bore so that the longitudinal seating surface of the wedge contacts the side surface of the cutting insert and for at least a portion of the length of the wedge the entire support surface contacts the bore wall so as to frictionally retain the cutting insert in the seat.

Abstract: A cutting tool assembly includes a support block having a concealable outer surface portion, first and second bores, and first and second fluid passages. The first fluid passage is in fluid communication with the first bore and the second fluid passage. The second fluid passage has an axis and extends between the concealable outer surface portion and the second bore. Furthermore, the second bore and the second fluid passage are configured such that the axis may be extended through the second bore and beyond the support block without intersecting the support block. The cutting tool assembly also includes a replaceable spray nozzle having a body that extends into the first bore such that the spray nozzle is in fluid communication with the first fluid passage.

Abstract: An excavation cutting tool holder retention assembly includes a support block having a tool holder bore, the tool holder bore having a bore interior surface. The excavation cutting tool holder retention assembly also includes a cutting tool holder having a shank portion, the shank portion having a shank engagement surface. The excavation cutting tool holder retention assembly further includes a locking member forced between the bore interior surface and the shank engagement surface so as to frictionally retain the shank portion of the cutting tool holder within the tool holder bore.

Abstract: In a voice messaging system, voice mailboxes can be designated as private boxes from which boxes messages can be forwarded, with their source identities concealed, to destination mailboxes. Communication of messages may be between remote VMS systems as well as between mailboxes in the same VMS system. The private designation may be made selectively by a subscriber to the public switched telephone network on a global basis or on an individual basis for each message. The global designation may be toggled on or off at any time by a call to the system with appropriate input from the subscriber. Optionally, the private designation may be made for an individual message during the call in which the message is stored in the subscriber's mailbox. While information identifying the source of a communicated message is concealed from the recipient, a response message may be communicated from the recipient mailbox back to the source mailbox or a third party mailbox designated by the source subscriber.

Abstract: This invention relates to an excavation cutting tool holder retention system. The excavation cutting tool holder retention system includes a support block having a tool holder bore. The excavation cutting tool holder retention system also includes a tool holder having an effective shank, the effective shank being expandably adjustable within the tool holder bore so as to retain the effective shank within the tool holder bore.

Abstract: A sleeve for securing a cutting bit within a block used for mining and construction application whereby a flange on the sleeve has an undercut portion to promote removal of the sleeve. Additionally, a block used to secure a cutting bit within a holder used for mining and construction applications as a flange which also has an undercut which may be utilized with an extraction tool to promote removal of the block from the holder.

Abstract: A cutting bit has a bit body which has a forward end and a rearward end. The bit body contains a seat at the forward end thereof. The bit body contains a bore intersecting the seat wherein a bore wall defines the bore. A cutting insert is received by the seat wherein the cutting insert presents a side surface facing the bore. A wedge has a generally longitudinal seating surface. The wedge has a support surface opposite to the longitudinal seating surface. The wedge is received within the bore so that the longitudinal seating surface of the wedge contacts the side surface of the cutting insert and for at least a portion of the length of the wedge the entire support surface contacts the bore wall so as to frictionally retain the cutting insert in the seat.

Abstract: A system and method is provided for using underused or unused local telephone company local loops to subscriber premises for providing to such premises a connection to an alternate service provider having a common channel signaling controlled switched network. The use of the local loop is leased to the service provider at a rate dependent upon the usage of the circuit. Information and data to permit efficient and convenient billing for leased usage of the loops is implemented by linking the common channel signaling control network of the telephone network and the common channel signaling control network of the service provider network. Common channel signaling control signals indicating call set-up and call tear-down are transmitted by the service provider's common channel signaling network to and stored in the telephone common channel signaling network in the storage of the controller therein to permit billing therefrom.

Abstract: A system and method is provided for using underused or unused local telephone company local loops to subscriber premises for providing to such premises a connection to an alternate service provider. The use of the local loop is leased to the ultimate service provider at a rate dependent upon the usage and nature of usage of the circuit. Information and data to permit efficient and convenient billing for leased usage of the loops is implemented by providing on the local loop a passive monitor. The monitor detects and temporarily stores data relating to the commencement and termination of the signaling, the time of day, and the nature of the signaling that occurs. Data collected from the monitors is stored at a monitor center from which it is transferred to a billing operation such as the telephone company Revenue Accounting Office (RAO). Switching is provided to permit optional usage of the loop by either the telephone company of the alternate service provider or both.

Abstract: The invention provides a method for automatically selecting a carrier network from a plurality of available networks to carry a telephone call (including MTS, video, data, etc.) for which toll charges are to be levied. The selection is made as a function of the call-type, and the method may be used, for example, to select a carrier, pre-subscribed to by a subscriber, for intra-LATA toll calls, inter-LATA and international calls. Alternatively, within a call-type, a carrier may be selected on the basis of toll rates, either on a per-call basis or by pre-subscription. A receiving end-office receiving a call from a calling station determines call-type and accesses a database whose contents either produce the identity of a preferred carrier for the call-type or the identity of the carrier having the lowest toll rate for the call. In any case, the identity of the carrier is returned from the database to the end-office and the end-office switch acts to connect the call to that carrier's network.

Abstract: A system and method is provided for using underused or unused local telephone company local loops to subscriber premises for providing to such premises a connection to an alternate service provider. The use of the local loop is leased to the ultimate service provider at a rate dependent upon the usage and nature of usage of the circuit. Information and data to permit efficient and convenient billing for leased usage of the loops is implemented by providing on the local loop a passive monitor. The monitors are connected with a signal switching point (SSP) and deliver a dialed number. The dialed number contains information regarding the commencement or termination of the usage of an identified local loop and an identification of the nature of such usage. This dialed number triggers the SSP to formulate a message containing the information and forward the same to a service control point (SCP). The SCP contains a database for storing and processing the information.