Abstract: Systems and methods for determining a cancer class of a subject are provided in which a plurality of sequence reads, in electronic form, are obtained from a biological sample of the subject. The sample comprises a plurality of cell-free DNA molecules including respective DNA molecules longer than a threshold length of less than 160 nucleotides. The plurality of sequence reads excludes sequence reads of cell-free DNA molecules in the plurality of cell-free DNA molecules longer than the threshold length. The plurality of sequence reads is used to identify a relative copy number at each respective genomic location in a plurality of genomic locations in the genome of the subject. The genetic information about the subject obtained from the sample and the genetic information consisting of the identification of the relative copy number at each respective genomic location, is applied to a classifier that determines the cancer class of the subject.

Abstract: System, method and computer-readable medium containing instructions for providing AV signals with open or closed captioning information. The system includes a speech-to-text processing system coupled to a signal separation processor and a signal combination processor for providing automated captioning for video broadcasts contained in AV signals. The method includes separating an audio signal from an AV signal, converting the audio signal to text data, encoding the original AV signal with the converted text data to produce a captioned AV signal and recording and displaying the captioned AV signal. The system may be mobile and portable and may be used in a classroom environment for producing recorded captioned lectures and used for broadcasting live, captioned lectures. Further, the system may automatically translate spoken words in a first language into words in a second language and include the translated words in the captioning information.

Abstract: System, method and computer-readable medium containing instructions for providing AV signals with open or closed captioning information. The system includes a speech-to-text processing system coupled to a signal separation processor and a signal combination processor for providing automated captioning for video broadcasts contained in AV signals. The method includes separating an audio signal from an AV signal, converting the audio signal to text data, encoding the original AV signal with the converted text data to produce a captioned AV signal and recording and displaying the captioned AV signal. The system may be mobile and portable and may be used in a classroom environment for producing recorded captioned lectures and used for broadcasting live, captioned lectures. Further, the system may automatically translate spoken words in a first language into words in a second language and include the translated words in the captioning information.