Patents by Inventor Robert H. Yolken

Robert H. Yolken has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240122893
    Abstract: Disclosed herein, are methods for treating, preventing or inhibiting a coronavirus infection or a disease or condition associated with a coronavirus infection. The methods can comprise administering to the subject one or more therapeutically effective doses of sulforaphane.
    Type: Application
    Filed: February 23, 2022
    Publication date: April 18, 2024
    Inventors: Lorraine V. Brando, Alvaro A. Ordonez, Robert H. Yolken, Sanjay K. Jain
  • Publication number: 20230083668
    Abstract: The present invention describes methods of identifying high-risk populations or individuals who have positive serology for T. gondii. These methods include obtaining a biological sample from a subject; determining the level of T. gondii cyst antigen antibody in the biological sample; and characterizing the biological sample in at least one of three categories.
    Type: Application
    Filed: September 26, 2022
    Publication date: March 16, 2023
    Inventors: Jianchun Xiao, Robert H. Yolken, Raphael P. Viscidi
  • Publication number: 20210080459
    Abstract: The present invention describes methods of identifying high-risk populations or individuals who have positive serology for T. gondii. These methods include obtaining a biological sample from a subject; determining the level of T. gondii cyst antigen antibody in the biological sample; and characterizing the biological sample in at least one of three categories.
    Type: Application
    Filed: September 14, 2020
    Publication date: March 18, 2021
    Inventors: Jianchun Xiao, Robert H. Yolken, Raphael P. Viscidi
  • Publication number: 20190128886
    Abstract: The present invention describes methods of identifying high-risk populations or individuals who have positive serology for T.gondii. These methods include obtaining a biological sample from a subject; determining the level of T.gondii cyst antigen antibody in the biological sample; and characterizing the biological sample in at least one of three categories.
    Type: Application
    Filed: April 27, 2017
    Publication date: May 2, 2019
    Applicant: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Jianchun Xiao, Robert H. Yolken, Raphael P. Viscidi
  • Patent number: 8431611
    Abstract: This disclosure provides improved derivatives of artemisinin; pharmaceutical compositions containing these compounds; methods for preparing these compounds and compositions; methods of using these compounds and compositions for preventing, controlling or treating infectious diseases including but not limited to parasitic infectious diseases such as T. gondii infection, trypanosome parasite infection, plasmodia parasite infection, and cryptosporidium parasite infection; methods for preventing, controlling or treating toxoplasma infection; and methods for treating psychiatric disorders associated with toxoplasma infection including but not limited to schizophrenia using the disclosed compounds and compositions alone or in combination with one or more antipsychotic drugs.
    Type: Grant
    Filed: October 19, 2007
    Date of Patent: April 30, 2013
    Assignee: Johns Hopkins University
    Inventors: Lorraine V. Brando, Gary H. Posner, John G. D'Angelo, Robert H. Yolken, Christopher P. Hencken, Lauren Woodard
  • Publication number: 20100093651
    Abstract: This disclosure provides improved derivatives of artemisinin; pharamaceutical compositions containing these compounds; methods for preparing these compounds and compositions; methods of using these compounds and compositions for preventing, controlling or treating infectious diseases including but not limited to parasitic infectious diseases such as T. gondii infection, trypanosome parasite infection, plasmodia parasite infection, and cryptosporidium parasite infection; methods for preventing, controlling or treating toxoplasma infection; and methods for treating psychiatric disorders associated with toxoplasma infection including but not limited to schizophrenia using the disclosed compounds and compositions alone or in combination with one or more antipsychotic drugs.
    Type: Application
    Filed: October 19, 2007
    Publication date: April 15, 2010
    Inventors: Lorraine V. Brando, Gary H. Posner, John G. D'Angelo, Robert H. Yolken, Christopher P. Hencken, Lauren Woodard
  • Patent number: 5667797
    Abstract: An anti-diarrheic product comprises a foodstuff and an anti-rotaviral agent such as human defatted fat globule membranes, the human milk macromolecular fraction, skim milk, curd, whey, the milk mucin complex, the 46 Kd app.MW glycoprotein, a polypeptide having an amino acid sequence having the rotavirus binding specificity of the 46 Kd app.MW HMFG glycoprotein or mixtures thereof. An anti-diarrheal kit comprises the anti-rotaviral agent of this invention and instructions for its use, and optionally a foodstuff. A method for inhibiting or countering rotavirus infection in mammalian cells comprises contacting the cells with an anti-rotaviral amount of the agent of this invention.
    Type: Grant
    Filed: April 1, 1996
    Date of Patent: September 16, 1997
    Assignees: Cancer Research Fund of Contra Costa, Senomed, Inc., The Johns Hopkins University School of Medicine
    Inventors: Jerry A. Peterson, David S. Newburg, Robert H. Yolken
  • Patent number: 5505955
    Abstract: An anti-diarrheic product comprises a foodstuff and an anti-rotaviral agent such as human defatted fat globule membranes, the human milk macromolecular fraction, the milk mucin complex, the 46 Kd apparent MW glycoprotein, a polypeptide having the rotavirus-binding specificity of the 46 Kd apparent MW HMFG glycoprotein, mixtures thereof, or mixtures thereof, and optionally skim milk, curd, and/or whey. They product of the invention is provided also as an anti-diarrheal kit, with instructions for its use. The product of the invention has therapeutic and prophylactic application for inhibiting the onset of, or countering, rotavirus infection and/or diarrhea, in a subject, such as for example, infants and children (infantile gasteroenteritis), travellers, and immunodeficient persons, including HIV positive and transplant patients.
    Type: Grant
    Filed: January 23, 1995
    Date of Patent: April 9, 1996
    Assignees: Senomed, Inc., Cancer Research Fund of Contra Costa, The Johns Hopkins Univ. School of Medicine
    Inventors: Jerry A. Peterson, Robert H. Yolken, David S. Newburg
  • Patent number: 5192551
    Abstract: The binding of neutral glycolipid GA1 (asialo-GM1) to a broad spectrum of enteric viruses is taught. The glycolipid can be used to pass through the gastrointestinal tract of adults and children to adsorb viral particles and remove them from the body. The glycolipid may be used alone or bound to a non-absorbable resin or matrix.
    Type: Grant
    Filed: May 2, 1989
    Date of Patent: March 9, 1993
    Assignee: Johns Hopkins University
    Inventors: Rodney E. Willoughby, Jr., Robert H. Yolken
  • Patent number: 4713328
    Abstract: A method is disclosed for efficient, rapid diagnosis of bacterial infections by measuring for the presence of beta-lactamase using .sup.14 C-benzylpenicillin as an enzyme substrate and isolating cleaved substrate with an ion exchange column.
    Type: Grant
    Filed: January 3, 1984
    Date of Patent: December 15, 1987
    Inventor: Robert H. Yolken