Abstract: Disclosed herein are methods of increasing the potency of saRNA encapsulated lipid nanoparticles (LNPs) through a novel and surprisingly superior LNP manufacturing technique. The method disclosed herein overcomes technical difficulties and high costs associated with previous LNP manufacturing techniques. The methods disclosed herein, therefore, greatly improve the industrial production of LNPs in unexpected ways thereby providing more potent and less expensive LNPs for nucleic acid delivery.

Abstract: A corner assembly for a sandwich panel system comprising an interior component with two or more flange portions arranged in an L- or T-shape and an exterior component, for securing the panels in a corner configuration.

Abstract: A corner assembly for a sandwich panel system comprising an interior component with two or more flange portions arranged in an L- or T-shape and an exterior component, for securing the panels in a corner configuration.

Abstract: A power generation system includes a power source that is configured to communicate with at least one of a downstream load or a downstream device by changing a voltage on a power bus between the power source and the at least one of the downstream load or the downstream device, while power source provides power on the power bus to the at least one of the downstream load or the downstream device.

Abstract: A portable fuel and lubricant delivery system for chainsaws is disclosed, comprising a wearable harness and a dual-container assembly. The system is designed to improve the operational efficiency and autonomy of chainsaw use by providing a continuous, automatic supply of fuel and lubricant directly to the chainsaw. One container within the assembly is dedicated to fuel, while the other holds lubricant. The containers are detachable and reconfigurable, accommodating various types and volumes of fuel and lubricants. An integral set of hoses, featuring a gravity feed mechanism, connects the containers to the chainsaw, ensuring a steady flow of fluids. The system further comprises a set of control valves or nozzles for connecting to the chainsaw's intake points, and the hoses are protected by a durable sheath. The invention is adaptable to various chainsaw models and other gas-powered tools, providing a versatile solution for fuel and lubricant delivery in demanding applications.

Abstract: The present invention relates to compositions and processes for the extraction of metals from solid material using non-aqueous solvents and oxidisers. The processes and compositions of the present invention are useful for selectively extracting metals from solid material, particularly electronic waste material.

Abstract: Systems and methods for processing electronic imaging data obtained from medical imaging procedures, with use of trained artificial intelligence (AI) models, are disclosed herein. In an example, a use of a medical evaluation workflow involving an AI model includes: obtaining image data and non-image data associated with a medical imaging study; using at least one AI model to analyze the image data, with the trained AI model being validated with a defined governance standard to identify a characteristic or particular type of characteristic; identifying the characteristic with the AI model; and communicating the identified characteristic to a location associated with evaluation of the medical imaging study.

Abstract: A light source comprising a pump LED for emitting a pump light having a peak wavelength of 420 to 430 nm, one or more wavelength converting materials configured for absorbing a portion of said pump light and converting said portion to converted light, and wherein emitted light is a combination of said converted light and said pump light, said emitted light having a first SPD between 380 and 780 nm having a first power, a second SPD between 440 and 490 nm having a second power, wherein said second power is no greater than 2% of said first power, and wherein said emitted light has a CRI of at least 85, an Rf of at least 60 a CIE whiteness of at least 70.

Abstract: A power generation system includes a power source that is configured to communicate with at least one of a downstream load or a downstream device by changing a voltage on a power bus between the power source and the at least one of the downstream load or the downstream device, while power source provides power on the power bus to the at least one of the downstream load or the downstream device.

Abstract: The present invention relates to processes for forming eutectic extracts, processes for purifying eutectic extracts and uses of the eutectic extracts such as in food-stuffs, pharmaceuticals, nutraceuticals and supplements, such as food supplements and sports supplements.

Abstract: A power generation system includes a power source that is configured to communicate with at least one of a downstream load or a downstream device by changing a voltage on a power bus between the power source and the at least one of the downstream load or the downstream device, while power source provides power on the power bus to the at least one of the downstream load or the downstream device.

Abstract: The assessment and ranking of machine learning models is sped up. In one embodiment, a plurality of model definitions are automatically tested and ranked according to their expected generalization ability. Other embodiments include assessing a single change to the model to determine if the change increases or decreases the model's generalization ability. This technique can also be applied to assess input data transformations used to develop the model.

Abstract: A retrievable seal guide (RSG) for installing a seal stem in a polished bore receptacle. The RSG has an outer grapple. Inside the grapple is a mandrel. At the end of the RSG is a bullet nose guide. The mandrel is spring loaded with a spring placed under the grapple Near the rear end of the guide is a plug with an o-ring. Note that the bullet nose has an opening formed in it. A channel is also formed down the length of the device. Note too that for tight formations of non-perforated liners the plug can be replaced with a stainless-steel ball that acts as a check valve. As the RSG is pulled out, the guide is pulled back, which compresses the spring forcing the mandrel back until a cam clears the collapsible fingers on the grapple, which allows the RSG to be withdrawn.

Abstract: A drilling wedge that has, in addition to a normal connector rod, two wings that extend from the sides of the wedge. These wings are angular members that fill much of the space in the larger casing around the wedge. These wings prevent a milling assembly from sliding past the wedge or from moving off to the side, where an exit through the pipe or casing in the wrong place can occur. Instead, the wings help to keep the milling assembly in the proper position on the tray of the wedge to ensure that the milling assembly reaches the proper exit point in the casing. The wings are retracted when the HEW is deployed through the narrower pipe. Once the HEW is properly positioned, the guide cone is extended and the wings are deployed.

Abstract: Systems and methods for processing electronic imaging data obtained from medical imaging procedures, with use of trained artificial intelligence (AI) models, are disclosed herein. In an example, a use of a medical evaluation workflow involving an AI model includes: obtaining image data and non-image data associated with a medical imaging study; using at least one AI model to analyze the image data, with the trained AI model being validated with a defined governance standard to identify a characteristic or particular type of characteristic; identifying the characteristic with the AI model; and communicating the identified characteristic to a location associated with evaluation of the medical imaging study.

Abstract: Provided herein are systems, methods and computer readable media for allocating sales commissions. In providing such functionality, a method may include, for example, receiving a set of transaction information for a transaction. The transaction information may include an indication of at least one product or service for which a sales commission is offered. The method may also include determining, based on the transaction information, whether a merchant is eligible to receive the sales commission, in response to determining that the transaction information does not identify a merchant that is eligible to receive the sales commission, selecting, using a processor, at least one merchant from a list of merchants selected from a plurality of merchants to receive the sales commission, and providing the sales commission to the selected at least one merchant.

Abstract: The present invention relates to processes for forming eutectic extracts, processes for purifying eutectic extracts and uses of the eutectic extracts such as in food-stuffs, pharmaceuticals, nutraceuticals and supplements, such as food supplements and sports supplements.

Abstract: The present invention relates to food products comprising Onyx sorghum capable of moderating blood glucose and insulin levels after consumption, thereby treating or preventing diabetes, and methods for the same.

Abstract: One embodiment of a securable and verifiable food delivery bag with a key component that is a panel (13) built seamlessly into the upper end (12). This element includes a pull strip (14) and an adhesive band (15) which allows the unit to be self-sealed. This panel (13) includes a Quick Response (QR) code (16) which may be utilized in a variety of capacities depending on factors such as the market, space and industry. Additionally incorporated is an identification number (17) which corresponds with QR code (16).

Abstract: The present disclosure provides a method that includes applying at least one radiofrequency saturation pulse at a frequency or a range of frequencies to substantially saturate magnetization corresponding to an exchangeable proton in the ROI to generate magnetic resonance (MR) data. The MR data is then acquired using an echo-planar imaging readout, which is configured to sample a series of gradient echo pulse trains at a series of gradient echo times and a series of spin echo pulse trains at a series of spin echo times. One or more relaxometry measurement is then computed using the MR data sampled at the gradient echo times and the spin echo times. An oxygen-weighted image is then generated using the one or more relaxometry measurement, and a pH-weighted image is generated using MR data sampled at one or more of the spin echo times or gradient echo times.