Abstract: A bottle assembly has a bottle and a removable cap. The cap includes a nozzle and a vent arrangement. The vent arrangement can include a vent conduit that extends into an air cavity present at the bottom of the bottle assembly when the bottle assembly is inverted. The vent arrangement allows for pressure equalization within the bottom assembly in response to liquid being dispensed from the bottle assembly to permit high flow rates of the dispensed liquid without squeezing of the bottle.

Abstract: A display article is described herein that includes: a substrate comprising a thickness and a primary surface; a textured surface region; and an antireflective coating disposed on the textured surface region. The textured surface region comprises structural features and an average texture height (Rtext) from 50 nm to 300 nm. The substrate exhibits a sparkle of less than 5%, as measured by PPD140, and a transmittance haze of less than 40%, at a 0° incident angle. The antireflective coating comprises alternating high refractive index and low refractive index layers. Each of the low index layers comprises a refractive index of less than or equal to 1.8, and each of the high index layers comprises a refractive index of greater than 1.8. The article also exhibits a first-surface average photopic specular reflectance (% R) of less than 0.3% at any incident angle from about 5° to 20° from normal at visible wavelengths.

Abstract: Adjustable concrete forms, typically fabricated from steel, allowing variation in the height, tilt, and shape of the form of gravity wall sections. The adjustable concrete form includes adjustable height vertical and sloped walls to change the height of the form through the operation of built-in mechanical jacks, such as ball screw assemblies. The separation distances at top and bottom of the walls can be adjusted by upper connectors (e.g., tie bars) and lower connectors (e.g., base straps). The same adjustable concrete form is assembled, used to pour a gravity wall section, disassembled, repositioned, and reassembled a virtually unlimited number of times to create varying height, tilt, and shape gravity wall sections for mile after of roadway construction.

Abstract: A display article is described herein that includes: a substrate comprising a thickness and a primary surface; and the primary surface having defined thereon a diffractive surface region. The diffractive surface region comprises a plurality of structural features that comprises a plurality of different heights in a multimodal distribution. Further, the substrate exhibits a sparkle of less than 4%, as measured by pixel power deviation (PPD140) at an incident angle of 0° from normal, a distinctness of image (DOI) of less than 80% at an incident angle of 20° from normal, and a transmittance haze of less than 20% from an incident angle of 0° from normal.

Abstract: Methods are described for improving flow of oil containing fluids through vessels, pipelines, heat exchangers, and other equipment. Polymeric surfactants with lipophilic head groups and long hydrophilic poly(ethene oxide) tails are added to the fluid to coat the oil and metal surfaces with drag reducing aqueous filaments, allowing the oil to slip past those surfaces without sticking and with little resistance. Such surface coatings also promote coalescence of viscous emulsions of water-in-oil or oil-in-water without creating oil-wet flow blocking residues on stationary surfaces. Such fouling obstructs the flow of oil and water and results in both material and energy losses.

Abstract: A method of distinguishing between proteinaceous and non-proteinaceous particulates in a fluid sample includes the steps of acquiring a brightfield background image of a membrane filter, introducing a fluid sample onto the membrane filter, acquiring a brightfield image of filtered particles resting on the membrane filter, generating a particle mask based on the brightfield background image and the brightfield image of filtered particles, introducing a fluorescent dye onto the membrane filter, detecting fluorescence on the particle mask, and distinguishing between proteinaceous and non-proteinaceous particulates based on the detected fluorescence. A method for detecting other types of particles, such as polysorbate particles, silicone oil or protein monomers is also disclosed.

Abstract: A bottle assembly has a bottle and a removable cap. The cap includes a nozzle and a vent arrangement. The vent arrangement can include a vent conduit that extends into an air cavity present at the bottom of the bottle assembly when the bottle assembly is inverted. The vent arrangement allows for pressure equalization within the bottom assembly in response to liquid being dispensed from the bottle assembly to permit high flow rates of the dispensed liquid without squeezing of the bottle.

Abstract: A vacuum manifold for filtration microscopy includes a manifold top having multiple openings, and a capture membrane positioned above and spaced apart from the manifold top, where the capture membrane is configured to deflect into contact with a surface of the manifold top when a negative pressure is applied to the multiple openings. A method for filtration microscopy includes the steps of providing a vacuum manifold including a manifold top having a plurality of openings, and a capture membrane positioned above and spaced apart from the manifold top; applying sample drops to sample spots on the membrane, the sample spots positioned above the plurality of openings; applying a negative pressure to the openings such that the capture membrane contacts a surface of the manifold top; and optically imaging particulates on the capture membrane.

Abstract: A system for characterizing at least one particle from a fluid sample is disclosed. The system includes a filter disposed upstream of an outlet, and a luminaire configured to illuminate the at least one particle at an oblique angle. An imaging device is configured to capture and process images of the illuminated at least one particle as it rests on the filter for characterizing the at least one particle. A system for characterizing at least one particle using bright field illumination is also disclosed. A method for characterizing particulates in a fluid sample using at least one of oblique angle and bright field illumination is also disclosed.

Abstract: A vacuum manifold for filtration microscopy includes a manifold top having multiple openings, and a capture membrane positioned above and spaced apart from the manifold top, where the capture membrane is configured to deflect into contact with a surface of the manifold top when a negative pressure is applied to the multiple openings. A method for filtration microscopy includes the steps of providing a vacuum manifold including a manifold top having a plurality of openings, and a capture membrane positioned above and spaced apart from the manifold top; applying sample drops to sample spots on the membrane, the sample spots positioned above the plurality of openings; applying a negative pressure to the openings such that the capture membrane contacts a surface of the manifold top; and optically imaging particulates on the capture membrane.

Abstract: A small-scale, batch-wise device to simulate high-shear, short-duration emulsification of fluids from various industrial processes at elevated temperatures and pressures for the purpose of determining the quality and stability of those emulsions under different conditions and with different additives. A threaded, transparent tube capable high temperature and pressure is fitted with a threaded bearing with a shaft sealed gas tight at two points with spring-loaded, internally-facing, open rings. A socket head on the external end of the shaft held on a high-speed motor-drive rotates mixing blades on the internal end of the shaft. Process fluids and additives are added to the tube with a vaporizing liquid. The tube is sealed, heated to the process temperature under pressure, then inverted onto the motor drive, by which the blades are rotated at high-speed for a short duration. The tube is righted and the emulsion observed over time at process temperature under pressure.

Abstract: A system for characterizing at least one particle from a fluid sample is disclosed. The system includes a filter disposed upstream of an outlet, and a luminaire configured to illuminate the at least one particle at an oblique angle. An imaging device is configured to capture and process images of the illuminated at least one particle as it rests on the filter for characterizing the at least one particle. A system for characterizing at least one particle using bright field illumination is also disclosed. A method for characterizing particulates in a fluid sample using at least one of oblique angle and bright field illumination is also disclosed.

Abstract: A system for characterizing at least one particle from a fluid sample is disclosed. The system includes a filter disposed upstream of an outlet, and a luminaire configured to illuminate the at least one particle at an oblique angle. An imaging device is configured to capture and process images of the illuminated at least one particle as it rests on the filter for characterizing the at least one particle. A system for characterizing at least one particle using bright field illumination is also disclosed. A method for characterizing particulates in a fluid sample using at least one of oblique angle and bright field illumination is also disclosed.

Abstract: A vacuum manifold for filtration microscopy includes a manifold top having multiple openings, and a capture membrane positioned above and spaced apart from the manifold top, where the capture membrane is configured to deflect into contact with a surface of the manifold top when a negative pressure is applied to the multiple openings. A method for filtration microscopy includes the steps of providing a vacuum manifold including a manifold top having a plurality of openings, and a capture membrane positioned above and spaced apart from the manifold top; applying sample drops to sample spots on the membrane, the sample spots positioned above the plurality of openings; applying a negative pressure to the openings such that the capture membrane contacts a surface of the manifold top; and optically imaging particulates on the capture membrane.

Abstract: The present disclosure describes a shoe that may be transformed from a high heel shoe to a low heel shoe. The shoe may include three parts: a removable stelo, a removable high heel attachment, and the corresponding attachment systems integrated into the base shoe sole. The removable high heel attachment may be a standard heel of any design, width and height that has a locking system comprising a threaded post located at the heel base. When the stelo and heel attachment are attached, the shoe may be a high heel shoe. When they are removed, the shoe may be a low heel shoe, or flat shoe.

Abstract: A vacuum manifold for filtration microscopy includes a manifold top having multiple openings, and a capture membrane positioned above and spaced apart from the manifold top, where the capture membrane is configured to deflect into contact with a surface of the manifold top when a negative pressure is applied to the multiple openings. A method for filtration microscopy includes the steps of providing a vacuum manifold including a manifold top having a plurality of openings, and a capture membrane positioned above and spaced apart from the manifold top; applying sample drops to sample spots on the membrane, the sample spots positioned above the plurality of openings; applying a negative pressure to the openings such that the capture membrane contacts a surface of the manifold top; and optically imaging particulates on the capture membrane.

Abstract: Methods for providing a computer implemented medical diagnosis are provided. In one aspect, a method includes receiving an input from a user comprising at least one symptom of the user, and providing the at least one symptom as an input to a medical model. The method also includes deriving estimates of the probability of the user having a disease from the discriminative model, inputting the estimates to the inference engine, performing approximate inference on the probabilistic graphical model to obtain a prediction of the probability that the user has that disease, and outputting the probability of the user having the disease for display by a display device.

Abstract: Methods for providing a computer implemented medical diagnosis are provided. In one aspect, a method includes receiving an input from a user comprising at least one symptom of the user, and providing the at least one symptom as an input to a medical model. The method also includes deriving estimates of the probability of the user having a disease from the discriminative model, inputting the estimates to the inference engine, performing approximate inference on the probabilistic graphical model to obtain a prediction of the probability that the user has that disease, and outputting the probability of the user having the disease for display by a display device.

Abstract: The present disclosure describes a shoe that may be transformed from a high heel shoe to a low heel shoe. The shoe may include three parts: a removable stelo, a removable high heel attachment, and the corresponding attachment systems integrated into the base shoe sole. The removable high heel attachment may be a standard heel of any design, width and height that has a locking system comprising a threaded post located at the heel base. When the stelo and heel attachment are attached, the shoe may be a high heel shoe. When they are removed, the shoe may be a low heel shoe, or flat shoe.

Abstract: A computer implemented method for developing a probabilistic graphical representation, the probabilistic graphical representation comprising nodes and links between the nodes indicating a relationship between the nodes, wherein the nodes represent conditions, the method comprising: using a language model to produce a context aware embedding for said condition; enhancing said embedding with one or more features to produce an enhanced embedded vector; and using a machine learning model to map said enhanced embedded vector to a value, wherein said value is related to the node representing said condition or a neighbouring node, wherein said machine learning model has been trained using said enhanced embedded vectors and observed values corresponding to said enhanced embedded vectors.