Patents by Inventor Robert Heger

Robert Heger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11964168
    Abstract: A method for treating a tumor, comprising identifying a tumor as a prostate cancer tumor and implanting in the tumor identified as a prostate cancer tumor, at least one diffusing alpha-emitter radiation therapy (DaRT) source with a suitable radon release rate and for a given duration, such that the source provides during the given duration a cumulated activity of released radon between 7 Mega becquerel (MBq) hour and 14.7 MBq hour, per centimeter length.
    Type: Grant
    Filed: January 9, 2023
    Date of Patent: April 23, 2024
    Assignee: ALPHA TAU MEDICAL LTD.
    Inventors: Itzhak Kelson, Yona Keisari, Amnon Gat, Robert Den, Ofer Magen, Vered Domankevich, Lior Arazi, Tomer Cooks, Guy Heger, Mirta Duman{hacek over (c)}ić, Ishai Luz, Maayan Hedva Vatarescu
  • Publication number: 20140135388
    Abstract: The present invention relates to self-emulsifying formulations based on an active ingredient component and a formulation base with a lipid component and with a binder component and to the use of this formulation as dosage form in the life science sector. The invention also describes a process for producing self-emulsifying formulations by mixing the formulation components to form a plastic mixture and, where appropriate, to manufacture the formulations as dosage form advantageously by use of melt extrusion. The formulations spontaneously form emulsions in water or aqueous media.
    Type: Application
    Filed: June 6, 2013
    Publication date: May 15, 2014
    Inventors: Gunther BERNDL, Joerg BREITENBACH, Robert HEGER, Joerg ROSENBERG, Michael STADLER, Peter WILKE
  • Patent number: 8470347
    Abstract: The present invention relates to self-emulsifying formulations based on an active ingredient component and a formulation base with a lipid component and with a binder component and to the use of this formulation as dosage form in the life science sector. The invention also describes a process for producing self-emulsifying formulations by mixing the formulation components to form a plastic mixture and, where appropriate, to manufacture the formulations as dosage form advantageously by use of melt extrusion. The formulations spontaneously form emulsions in water or aqueous media.
    Type: Grant
    Filed: May 29, 2001
    Date of Patent: June 25, 2013
    Assignee: AbbVie Deutschland GmbH and Co KG
    Inventors: Gunther Berndl, Jörg Breitenbach, Robert Heger, Michael Stadler, Peter Wilke, Jörg Rosenberg
  • Publication number: 20120225953
    Abstract: The present invention relates to self-emulsifying formulations based on an active ingredient component and a formulation base with a lipid component and with a binder component and to the use of this formulation as dosage form in the life science sector. The invention also describes a process for producing self-emulsifying formulations by mixing the formulation components to form a plastic mixture and, where appropriate, to manufacture the formulations as dosage form advantageously by use of melt extrusion. The formulations spontaneously form emulsions in water or aqueous media.
    Type: Application
    Filed: April 18, 2012
    Publication date: September 6, 2012
    Applicant: ABBOTT GMBH & CO. KG
    Inventors: Gunther Berndl, Jörg Breitenbach, Robert Heger, Michael Stadler, Peter Wilke, Jörg Rosenberg
  • Patent number: 8197829
    Abstract: The present invention relates to self-emulsifying formulations based on an active ingredient component and a formulation base with a lipid component and with a binder component and to the use of this formulation as dosage form in the life science sector. The invention also describes a process for producing self-emulsifying formulations by mixing the formulation components to form a plastic mixture and, where appropriate, to manufacture the formulations as dosage form advantageously by use of melt extrusion. The formulations spontaneously form emulsions in water or aqueous media.
    Type: Grant
    Filed: May 29, 2001
    Date of Patent: June 12, 2012
    Assignee: Abbott Laboratories
    Inventors: Gunther Berndl, Jörg Breitenbach, Robert Heger, Michael Stadler, Peter Wilke, Jörg Rosenberg
  • Publication number: 20110123652
    Abstract: The present invention relates to self-emulsifying formulations based on an active ingredient component and a formulation base with a lipid component and with a binder component and to the use of this formulation as dosage form in the life science sector. The invention also describes a process for producing self-emulsifying formulations by mixing the formulation components to form a plastic mixture and, where appropriate, to manufacture the formulations as dosage form advantageously by use of melt extrusion. The formulations spontaneously form emulsions in water or aqueous media.
    Type: Application
    Filed: October 6, 2010
    Publication date: May 26, 2011
    Inventors: Gunther Berndl, Jörg Breitenbach, Jörg Rosenberg, Robert Heger, Michael Stadler, Peter Wilke
  • Publication number: 20100189994
    Abstract: Aqueous dispersions of crosslinked emulsion polymers comprising tertiary ester groups, comprising (a) at least 50% by weight of an ester derived from a tertiary alcohol and an ethylenically unsaturated C3 to C5 carboxylic acid, (b) 0.001% to 5.0% by weight of at least one compound having at least two ethylenically unsaturated double bonds, and (c) 0% to 49.999% by weight of at least one other monoethylenically unsaturated compound in interpolymerized form and having an average particle size of not more than 1000 nm, and water-absorbing materials obtainable by coating a backing material with the aqueous dispersion described of crosslinked emulsion polymers comprising tertiary ester groups, drying and heating the thus treated backing material to a temperature of at least 140° C. to form carboxyl groups from the tertiary ester groups of the emulsion polymer and at least partly neutralizing the carboxyl groups, and also the use of the water-absorbing materials as an absorbent for water and aqueous fluids.
    Type: Application
    Filed: August 6, 2007
    Publication date: July 29, 2010
    Applicant: BASF SE
    Inventors: Marc Bothe, Hermann Seyffer, Mirjam Herrlich-Loos, Robert Heger, Matthias Weismantel
  • Patent number: 7687071
    Abstract: Nanoparticulate preparations of pharmaceutical and cosmetic active substances with a core-shell structure, whereby the active substance is present in an X-ray amorphous form, together with a polymer matrix and the shell consists of a stabilizing sheathing matrix.
    Type: Grant
    Filed: December 7, 1999
    Date of Patent: March 30, 2010
    Assignee: BASF Aktiengesellschaft
    Inventors: Robert Heger, Helmut Auweter, Jörg Breitenbach, Heribert Bohn
  • Patent number: 7393840
    Abstract: The present invention relates to formulations based on at least one heparin, glycosaminoglycan or heparinoid and on a formulation base with a lipid component and a polymer component. The use of this formulation as drug form for oral administration of at least one heparin, glycosaminoglycan or heparinoid, and also a process for producing the formulations by mixing the formulation components to form a plastic mixture and, where appropriate, to manufacture the formulations as drug form, advantageously using melt extrusion, are described. The lipid component advantageously has active ingredient-promoting properties, while the polymer component is soluble or swellable. At least parts of the lipid component are embedded in a polymer matrix, preferably in the form of a molecular dispersion. The formulations can form emulsions in water or aqueous liquids.
    Type: Grant
    Filed: May 29, 2001
    Date of Patent: July 1, 2008
    Assignee: BASF Aktiengesellschaft
    Inventors: Jörg Rosenberg, Jörg Breitenbach, Dieter Herr, Volker Laux, Robert Heger
  • Patent number: 6844377
    Abstract: Dye-containing polymer particles of at least one dye in a matrix of an essentially water-insoluble polymer and having an average particle size within the range from 5 nm to 5 ?m are prepared by a process which comprises precipitating the dye-containing polymer particles from a solution of the polymer and of the dye in a water-miscible organic solvent by addition of an aqueous phase thereto.
    Type: Grant
    Filed: September 29, 1999
    Date of Patent: January 18, 2005
    Assignee: BASF Aktiengesellschaft
    Inventors: Helmut Auweter, Heribert Bohn, Robert Heger, Ulrike Schlösser, Karl Siemensmeyer
  • Publication number: 20040266626
    Abstract: The invention relates to a solid crop protection formulation comprising
    Type: Application
    Filed: May 5, 2004
    Publication date: December 30, 2004
    Inventors: Wolfgang Schrof, Robert Heger, Sebastian Koltzenburg, Matthias Bratz, Cyrill Zagar, Dieter Horn
  • Publication number: 20040242427
    Abstract: The invention relates to a solid crop protection formulation comprising
    Type: Application
    Filed: May 6, 2004
    Publication date: December 2, 2004
    Inventors: Sebastian Koltzenburg, Wolfgang Schrof, Michael Seufert, Robert Heger, Stephan Lehmann, Uwe Kardorff, Cyrill Zagar, Matthias Bratz, Eric D. Carlson, Han Ting Chang, Sigrid C. Kuebler
  • Publication number: 20040013697
    Abstract: The present invention relates to self-emulsifying formulations based on an active ingredient component and a formulation base with a lipid component and with a binder component and to the use of this formulation as dosage form in the life science sector. The invention also describes a process for producing self-emulsifying formulations by mixing the formulation components to form a plastic mixture and, where appropriate, to manufacture the formulations as dosage form advantageously by use of melt extrusion. The formulations spontaneously form emulsions in water or aqueous media.
    Type: Application
    Filed: November 25, 2002
    Publication date: January 22, 2004
    Inventors: Gunther Berndl, Jorg Breitenbach, Robert Heger, Michael Stadler, Peter Wilke, Jorg Rosenberg
  • Patent number: 6649721
    Abstract: Antifoams and/or deaerators are based on oil-in-water emulsions which contain, in the hydrophobic oil phase, at least one compound effective as an antifoam and/or deaerator and, if required, further components, the oil-in-water emulsions containing from 0.01 to 3% by weight of a water-soluble, amphiphilic copolymer having acid groups or of a water-soluble salt thereof as a stabilizer.
    Type: Grant
    Filed: February 8, 2001
    Date of Patent: November 18, 2003
    Assignee: BASF Aktiengesellschaft
    Inventors: Rainer Dyllick-Brenzinger, Günther Glas, Primoz Lorencak, Robert Heger, Günter Oetter
  • Patent number: 6624219
    Abstract: The present invention relates to a set of (co)polymers, dispersion formulations, solid solutions and formulation conditions able to disperse a dye selected from the group of a monoazo dye, quinophthalone dye and an anthraquinone dye in a stable nanoparticular form in an aqueous medium.
    Type: Grant
    Filed: August 17, 2000
    Date of Patent: September 23, 2003
    Assignees: BASF Aktiengesellschaft, SYMYX Technologies, Inc.
    Inventors: Robert Heger, Wolfgang Schrof, Michael Seufert, Helmut Auweter, Walter Mächtle, Rüdiger Iden, Dieter Horn, Ralph Nielsen, Eric Carlson, Chang Han-Ting, Sigrid Kuebler, Petro Miroslav
  • Publication number: 20030161884
    Abstract: The present invention relates to formulations based on at least one heparin, glycosaminoglycan or heparinoid and on a formulation base with a lipid component and a polymer component. The use of this formulation as drug form for oral administration of at least one heparin, glycosaminoglycan or heparinoid, and also a process for producing the formulations by mixing the formulation components to form a plastic mixture and, where appropriate, to manufacture the formulations as drug form, advantageously using melt extrusion, are described. The lipid component advantageously has active ingredient-promoting properties, while the polymer component is soluble or swellable. At least parts of the lipid component are embedded in a polymer matrix, preferably in the form of a molecular dispersion. The formulations can form emulsions in water or aqueous liquids.
    Type: Application
    Filed: November 25, 2002
    Publication date: August 28, 2003
    Inventors: Jorg Rosenberg, Jorg Breitenbach, Dieter Herr, Volker Laux, Robert Heger
  • Publication number: 20030143166
    Abstract: The invention relates to aqueous dispersions of sparingly water-soluble or water-insoluble organic UV filter substances, which comprise at least one sparingly water-soluble or water-insoluble organic UV filter substance as colloidally disperse phase in amorphous or partially amorphous form.
    Type: Application
    Filed: January 13, 2003
    Publication date: July 31, 2003
    Inventors: Robert Heger, Helmut Auweter, Wilma M. Dausch, Georg Konrad Zwissler, Thomas Wunsch
  • Patent number: 6599931
    Abstract: A test system for characterizing the compatibility of bioactive substances with polyvinylpyrrolidones in a solid dispersion consisting of one or more bioactive substances and 1,3-bis(1-pyrrolidonyl)butane.
    Type: Grant
    Filed: September 18, 1999
    Date of Patent: July 29, 2003
    Assignee: Abbott GmbH & Co. KG
    Inventors: Jörg Breitenbach, Robert Heger, Dirk Simon, Bernd Liepold
  • Patent number: 6531117
    Abstract: The invention relates to aqueous dispersions of sparingly water-soluble or water-insoluble organic UV filter substances, which comprise at least one sparingly water-soluble or water-insoluble organic UV filter substance as colloidally disperse phase in amorphous or partially amorphous form.
    Type: Grant
    Filed: January 30, 2001
    Date of Patent: March 11, 2003
    Assignee: BASF Aktiengesellschaft
    Inventors: Robert Heger, Helmut Auweter, Wilma M. Dausch, Georg Konrad Zwissler, Thomas Wünsch
  • Patent number: 6494924
    Abstract: The dyes have an average particle size within the range from 5 nm to 1 &mgr;m and a variance of less than 50%. They are especially useful for ink-jet ink preparations.
    Type: Grant
    Filed: October 3, 2000
    Date of Patent: December 17, 2002
    Assignee: BASF Aktiengesellschaft
    Inventors: Helmut Auweter, Heribert Bohn, Robert Heger, Dieter Horn, Bernd Siegel, Karl Siemensmeyer