Abstract: A diabetes therapy device is disclosed herein, which includes a profile memory storing a parameter profile and a dedicated reference time mark. The parameter profile defines at least one parameter that is associated with insulin administration as a function of time for a generally circadian chronobiological cycle. The reference time mark indicates the beginning of the circadian chronobiological cycle and initializes a running time. Insulin amounts to be administered are determined as a function of the running time in accordance with a current matching of the parameter profile. A modified matching based on the reference time mark and an upcoming trigger time is computed and is time-shifted from the current matching, wherein the modified matching is applied by making the modified matching the current matching, such that future insulin amounts to be administered are determined in accordance with the modified matching.

Abstract: A method for calculating a bolus amount, wherein the bolus amount is calculated according to a basal rate, and a device for calculating a bolus amount according to the method, the device including an input unit used to input an amount of received carbohydrates, a computer coupled to the input unit and at least one interface used to transmit an actual blood glucose value and the value of the actual basal rate to the computer, wherein the at least one interface or another interface transmits a bolus amount calculated by the computer.

Abstract: Insulin pump programming software is disclosed that permits selectively modifying insulin pump configuration files. The software facilitates retrieving a source file consisting of a configuration file or portion thereof from a source location. The source file may include general configuration data and insulin delivery data. Once retrieved, the source file may be edited, then the entire source file or a portion thereof may be saved to a target configuration file at one or more target locations. Only the portion of the target configuration file corresponding to the saved source file or portion thereof is replaced by the source file.

Abstract: Insulin pump programming software is disclosed that generates thumbnail images of basal rate profile data contained in source files and displays the images to permit an operator to select the desired profile data without opening the source files. The software also permits the operator to verify changes to pump profiles before programming the pump by displaying thumbnail images of the current pump profile and the new pump profile.

Abstract: The present invention relates to a pressure-difference warning system comprising an acoustic signal device, comprising an energy supply device and comprising a pressure sensor. The pressure sensor is designed for measuring a pressure difference between an interior region and an exterior region. The energy supply device is designed for providing energy for operating the warning system. The acoustic signal device is designed for outputting an acoustic signal if the measured pressure difference exceeds a specifiable threshold value.

Abstract: An electronic device may be configured to prompt a user via an on-board display to measure user glucose via an on-board glucose meter, to compute a first drug bolus value based on the measured user glucose, to display the first drug bolus value on the display and prompt the user via the display to enter carbohydrate information into the device, to compute a second drug bolus value based on the entered carbohydrate information, to display the second drug bolus value on the display and prompt the user via the display to enter user health information into the device, to compute a third drug bolus value based on the entered health information and a total drug bolus value as a sum of the first, second and third drug bolus values, and to display the third and total drug bolus values on the display.

Abstract: A diabetes therapy device is disclosed herein, which includes a profile memory storing a parameter profile and a dedicated reference time mark. The parameter profile defines at least one parameter that is associated with insulin administration as a function of time for a generally circadian chronobiological cycle. The reference time mark indicates the beginning of the circadian chronobiological cycle and initializes a running time. Insulin amounts to be administered are determined as a function of the running time in accordance with a current matching of the parameter profile. A modified matching based on the reference time mark and an upcoming trigger time is computed and is time-shifted from the current matching, wherein the modified matching is applied by making the modified matching the current matching, such that future insulin amounts to be administered are determined in accordance with the modified matching.

Abstract: A method of computing an insulin bolus quantity when a measured glucose value in a current time interval exceeds a target glucose value for the current time interval and when a time duration of glucose lowering action of the bolus to be administered spans the current and a number of the next adjacent time intervals, may comprise determining a corresponding number of percentages of insulin action of the recommended bolus quantity that will each be used lowering the glucose level during a respective one of the number of time intervals, and computing the recommended bolus quantity as a function of the measured glucose value, the target blood glucose level for a last one of the number of next adjacent time intervals, the insulin sensitivities for the current and each of the number of next adjacent time intervals, and the corresponding number of percentages.

Abstract: An electronic device may be configured to prompt a user via an on-board display to measure user glucose via an on-board glucose meter, to compute a first drug bolus value based on the measured user glucose, to display the first drug bolus value on the display and prompt the user via the display to enter carbohydrate information into the device, to compute a second drug bolus value based on the entered carbohydrate information, to display the second drug bolus value on the display and prompt the user via the display to enter user health information into the device, to compute a third drug bolus value based on the entered health information and a total drug bolus value as a sum of the first, second and third drug bolus values, and to display the third and total drug bolus values on the display.

Abstract: Insulin pump programming software is disclosed that permits selectively modifying insulin pump configuration files. The software facilitates retrieving a source file consisting of a configuration file or portion thereof from a source location. The source file may include general configuration data and insulin delivery data. Once retrieved, the source file may be edited, then the entire source file or a portion thereof may be saved to a target configuration file at one or more target locations. Only the portion of the target configuration file corresponding to the saved source file or portion thereof is replaced by the source file.

Abstract: Insulin pump programming software is disclosed that generates thumbnail images of basal rate profile data contained in source files and displays the images to permit an operator to select the desired profile data without opening the source files. The software also permits the operator to verify changes to pump profiles before programming the pump by displaying thumbnail images of the current pump profile and the new pump profile.

Abstract: A system and method are provided for generating a plurality of basal rate models that together model delivery of a corresponding plurality of basal rates of a diabetes treatment drug to a patient over a period of time. Information may be collected from a plurality of patients that have a diabetic condition and to which the diabetes treatment drug has been delivered. The collected information may include a glycemic control indicator for each of the plurality of patients that is indicative of an efficacy of the diabetes treatment drug in treating the patient's diabetic condition. The collected information may be filtered based on the glycemic control indicators to produce a subset of information that includes information only for patients that exhibit acceptable glycemic control. The plurality of basal rate models may be generated based on the subset of the collected information, and may be stored in a memory unit.

Abstract: A system for recommending insulin bolus quantities to an insulin user includes a display unit and memory unit coupled to a control circuit with a user blood glucose target stored in the memory unit. The control circuit is programmed to receive the user's current blood glucose value, to determine and display via the display unit a recommended correction insulin bolus quantity if the current blood glucose value exceeds the blood glucose target, to compute a difference value as the current blood glucose value less the blood glucose target, and to produce a modified blood glucose target as a sum of the blood glucose target and the difference value for a lock-out time period if the difference value is positive. Additional correction insulin bolus quantities may be recommended during the lock-out time period if the user's current blood glucose value exceeds the modified blood glucose target.

Abstract: The present invention relates to a pressure-difference warning system comprising an acoustic signal device, comprising an energy supply device and comprising a pressure sensor. The pressure sensor is designed for measuring a pressure difference between an interior region and an exterior region. The energy supply device is designed for providing energy for operating the warning system. The acoustic signal device is designed for outputting an acoustic signal if the measured pressure difference exceeds a specifiable threshold value.

Abstract: A system for recommending insulin bolus quantities to an insulin user includes a display unit and memory unit coupled to a control circuit with a user blood glucose target stored in the memory unit. The control circuit is programmed to receive the user's current blood glucose value, to determine and display via the display unit a recommended correction insulin bolus quantity if the current blood glucose value exceeds the blood glucose target, to compute a difference value as the current blood glucose value less the blood glucose target, and to produce a modified blood glucose target as a sum of the blood glucose target and the difference value for a lock-out time period if the difference value is positive. Additional correction insulin bolus quantities may be recommended during the lock-out time period if the user's current blood glucose value exceeds the modified blood glucose target.

Abstract: A method for calculating a bolus amount, wherein the bolus amount is calculated according to a basal rate, and a device for calculating a bolus amount according to the method, the device including an input unit used to input an amount of received carbohydrates, a computer coupled to the input unit and at least one interface used to transmit an actual blood glucose value and the value of the actual basal rate to the computer, wherein the at least one interface or another interface transmits a bolus amount calculated by the computer.

Abstract: A system for recommending insulin bolus quantities to an insulin user includes a display unit and memory unit coupled to a control circuit with a user blood glucose target stored in the memory unit. The control circuit is programmed to receive the user's current blood glucose value, to determine and display via the display unit a recommended correction insulin bolus quantity if the current blood glucose value exceeds the blood glucose target, to compute a difference value as the current blood glucose value less the blood glucose target, and to produce a modified blood glucose target as a sum of the blood glucose target and the difference value for a lock-out time period if the difference value is positive. Additional correction insulin bolus quantities may be recommended during the lock-out time period if the user's current blood glucose value exceeds the modified blood glucose target.

Abstract: A method of computing an insulin bolus quantity when a measured glucose value in a current time interval exceeds a target glucose value for the current time interval and when a time duration of glucose lowering action of the bolus to be administered spans the current and a number of the next adjacent time intervals, may comprise determining a corresponding number of percentages of insulin action of the recommended bolus quantity that will each be used lowering the glucose level during a respective one of the number of time intervals, and computing the recommended bolus quantity as a function of the measured glucose value, the target blood glucose level for a last one of the number of next adjacent time intervals, the insulin sensitivities for the current and each of the number of next adjacent time intervals, and the corresponding number of percentages.

Abstract: A system for recommending insulin bolus quantities to an insulin user includes a display unit and memory unit coupled to a control circuit with a user blood glucose target stored in the memory unit. The control circuit is programmed to receive the user's current blood glucose value, to determine and display via the display unit a recommended correction insulin bolus quantity if the current blood glucose value exceeds the blood glucose target, to compute a difference value as the current blood glucose value less the blood glucose target, and to produce a modified blood glucose target as a sum of the blood glucose target and the difference value for a lock-out time period if the difference value is positive. Additional correction insulin bolus quantities may be recommended during the lock-out time period if the user's current blood glucose value exceeds the modified blood glucose target.