Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.

Abstract: Pharmaceutical compositions comprising a stress protein complex and related molecules encoding or cells presenting such a complex are provided. The stress protein complex comprises an hsp110 or grp170 polypeptide complexed with an immunogenic polypeptide. The immunogenic polypeptide of the stress protein complex can be associated with a cancer or an infectious disease. Preferred immunogenic polypeptides include gp100, her2/neu ECD-PD, ICD and M. tuberculosis antigens. The pharmaceutical compositions of the invention can be used for the treatment or prevention of cancer or infectious disease.

Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.

Abstract: A digital camera for capturing and processing images of different resolutions and a corresponding method for down-scaling a digital image are provided. The method includes forming an image of a real scene on an image sensor that is made up of a plurality of pixels arranged in a matrix. The method further includes addressing and reading pixels in the matrix to obtain analog quantities related to the pixels luminance values, converting the analog quantities from the pixels matrix into digital values, and processing the digital values to obtain a data file representing the image of the real scene. To reduce computation time and power consumption, the addressing and reading of the pixels includes selecting a group of pixels from the matrix, and storing the analog quantities related to the pixels of the selected group of pixels into an analog storing circuit. The stored analog quantities are averaged to obtain an analog quantity corresponding to an average pixel luminance value.

Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.

Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly prostate cancer, are disclosed. Illustrative compositions comprise one or more prostate-specific polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly prostate cancer.

Abstract: The described embodiments relate generally to methods, systems and devices for maintaining data integrity of a removable media card of a handheld electronic device, particularly when such media card is removed from such device.

Abstract: The present invention is a system and method for automatically generating documents such as those required for divorce, eviction and small claims proceedings and other legal actions. A preferred embodiment of the system includes a server computer system and a user computer system connected to a network. The server computer system includes a memory for the storage of location-based divorce, eviction and small claims proceeding rules, a processor and a graphical user interface component. The user computer system includes a user interface component coupled to a processing component. The user interface component presents the graphical user interfaces generated by the graphical user interface component and receives responses to the presented graphical user interfaces. The responses include a selection of the location for the proceedings. The received responses are sent to the server and the server processor automatically generates documents based on the responses received.

Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.

Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.

Abstract: A fluid cleaning apparatus and method for use with a fluid interface that has structure for creating a fluid flowrate of a selected fluid, wherein the apparatus includes a housing that has a surrounding side wall about a longitudinal axis, the sidewall defining an interior between proximal end and distal end portions. The proximal end portion removably engages the fluid interface with fluid communication between the interior and the structure for creating the selected fluid's flowrate, the distal end portion including an aperture that is in fluid communication with the interior. Also included with the apparatus is an agitation element that is disposed adjacent to the distal end portion such that the aperture is in fluid communication with the agitation element and an external environment, wherein operationally the agitation element helps to dislodge a particulate from a selected surface in conjunction with the selected fluid to clean the selected surface.

Abstract: Pharmaceutical compositions comprising a stress protein complex and related molecules encoding or cells presenting such a complex are provided. The stress protein complex comprises an hsp110 or grp170 polypeptide complexed with an immunogenic polypeptide. The immunogenic polypeptide of the stress protein complex can be associated with a cancer or an infectious disease. Preferred immunogenic polypeptides include gp100, her2/neu ECD-PD, ICD and M. tuberculosis antigens. The pharmaceutical compositions of the invention can be used for the treatment or prevention of cancer or infectious disease.

Abstract: Pharmaceutical compositions comprising a stress protein complex and related molecules encoding or cells presenting such a complex are provided. The stress protein complex comprises an hsp110 or grp170 polypeptide complexed with an immunogenic polypeptide. The immunogenic polypeptide of the stress protein complex can be associated with a cancer or an infectious disease. Preferred immunogenic polypeptides include gp100, her2/neu ECD-PD, ICD and M. tuberculosis antigens. The pharmaceutical compositions of the invention can be used for the treatment or prevention of cancer or infectious disease.

Abstract: A composition for the protection, treatment and repair and for reducing the inflammation of connective tissue in mammals and a method for the treatment of connective tissue in mammals by the administration of the composition. The composition includes S-Adenosylmethionine (SAM), and a component selected from an aminosugar or salts thereof (e.g., glucosamine) or glycosaminoglycans (e.g., chondroitin salts) or mixtures or fragments thereof. The composition optionally includes manganese which promotes the production of connective tissue matrix. The composition also optionally includes methyl donors or methyl donor cofactors, such as vitamin B12, vitamin B6, folic acid, dimethylglycine or trimethylglycine.

Abstract: A polishing apparatus comprising a base for affixing structures thereto, a drive wheel, a polishing wheel assembly, a polishing belt, and at least one routing wheel engaged with the polishing belt. The polishing wheel assembly includes an elongated arm including a distal end, and a rotatable polishing wheel supported at the distal end of the elongated arm. The polishing belt is made with an abrasive outer surface to perform the polishing, and an inner surface for engagement with the perimeters of the drive wheel and the polishing wheel. The routing wheel is engaged with the outer surface of the polishing belt, such that the contact arc of the polishing belt with the polishing wheel differs from an arc of the polishing wheel perimeter extending from a first tangent line between the drive wheel and the polishing wheel to a second tangent line between the drive wheel and the polishing wheel.

Abstract: A solid state image sensor has an array of pixels in which each column has a reset voltage line and a read line. The sensor is reset and read a row at a time, with reset-related values held in a frame buffer for subsequent subtraction from read values. Reset-related values are derived in each column by sampling the voltage during reset on one capacitor and the voltage on release of reset on a second capacitor, and differencing these values to provide an output for the frame buffer. This provides a reduction in the size of frame buffer which would otherwise be required.

Abstract: The image sensor makes use of a distributed amplifier having its non-inverting input provided by a pixel amplifier transistor, and its inverting input and output provided in the pixel's column circuitry. The distributed amplifier is directly integrated with the image sensor's ADC circuit, and sampling and autozero are performed in a single step, thus reducing the number of noise contributions made by the components of the image sensor's readout chain.

Abstract: An image sensor has an array of pixels read by column circuits to provide reset and read samples on a pair of sample capacitors. To alleviate the effects of parasitic capacitance in the region of the sample capacitors, a modified timing arrangement is used. Both sample switches are operated simultaneously to pre-charge both sample capacitors with a pixel signal value. One sample switch is operated after reset to apply a reset value to one of the pre-charged sample capacitors.

Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.

Abstract: An image sensor includes an array of pixels arranged in rows and columns. A reference current source provides the reference current to a transistor forming one half of a current mirror. Each column has a current source, which forms the other half of a current mirror. A switch is provided to selectively connect a resistance between ground and the transistor. When the resistance is connected, the transistor is starved of gate-source voltage, which reduces the current supplied by each current source.