Patents by Inventor Robert Hice

Robert Hice has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of Cyt1Aa as broad spectrum targeting domain for insecticidal proteins with basic research and biotechnology applications
    Patent number: 10472397
    Abstract: A chimeric protein comprising a cytolytic ?-endotoxin portion and a heterologous polypeptide portion is provided. Nucleic acids encoding the chimeric protein are also provided. In some cases, the chimeric protein can be expressed in parasporal inclusions of Bacillus thuringiensis. In certain cases, the cytolytic ?-endotoxin portion can include Cyt1Aa, and the heterologous portion can include an insecticidal polypeptide. The chimeric protein can be expressed in a suitable B. thuringiensi cell and purified as parasporal inclusions. Also provided is a method of controlling insects by exposing an insect to a chimerical insecticidal protein.
    Type: Grant
    Filed: July 10, 2017
    Date of Patent: November 12, 2019
    Assignee: The Regents of the University of California
    Inventors: Brian A. Federici, Dennis Bideshi, Hyun-Woo Park, Robert Hice, Tianyun Su
  • USE OF Cyt1Aa AS BROAD SPECTRUM TARGETING DOMAIN FOR INSECTICIDAL PROTEINS WITH BASIC RESEARCH AND BIOTECHNOLOGY APPLICATIONS
    Publication number: 20180086796
    Abstract: A chimeric protein comprising a cytolytic ?-endotoxin portion and a heterologous polypeptide portion is provided. Nucleic acids encoding the chimeric protein are also provided. In some cases, the chimeric protein can be expressed in parasporal inclusions of Bacillus thuringiensis. In certain cases, the cytolytic ?-endotoxin portion can include Cyt1Aa, and the heterologous portion can include an insecticidal polypeptide. The chimeric protein can be expressed in a suitable B. thuringiensi cell and purified as parasporal inclusions. Also provided is a method of controlling insects by exposing an insect to a chimerical insecticidal protein.
    Type: Application
    Filed: July 10, 2017
    Publication date: March 29, 2018
    Inventors: Brian A. Federici, Dennis Bideshi, Hyun-Woo Park, Robert Hice, Tianyun Su