Patents by Inventor Robert Hoerr

Robert Hoerr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190193109
    Abstract: A nanoparticle coated hydrogel may be formed by a method of electrospraying nanoparticles on to a surface includes providing a drug and polymer combination in solvent to an inner capillary of a coaxial dual capillary spray nozzle. A coating with a drug that releases over time may be provided. Open and closed matrixes may be selectively formed to help modify time release periods.
    Type: Application
    Filed: March 1, 2019
    Publication date: June 27, 2019
    Inventors: Robert A. Hoerr, John V. Carlson
  • Patent number: 10252289
    Abstract: A nanoparticle coated hydrogel may be formed by a method of electrospraying nanoparticles on to a surface includes providing a drug and polymer combination in solvent to an inner capillary of a coaxial dual capillary spray nozzle. A coating with a drug that releases over time may be provided. Open and closed matrixes may be selectively formed to help modify time release periods.
    Type: Grant
    Filed: August 14, 2015
    Date of Patent: April 9, 2019
    Assignee: NANOCOPOEIA, INC.
    Inventors: Robert A. Hoerr, John V. Carlson
  • Patent number: 9642694
    Abstract: Devices to deliver one or more active ingredients for medical treatment may include a body of material presenting a surface including a polymer adapted to be rendered conductive such that one or more layers of electrospray particles are formable thereon or a body of conductive material presenting a surface upon which one or more layers of electrospray particles are formable thereon. A coating formed of electrospray particles may be deposited to adhere on the surface of the body of material (e.g., the coating may include one or more layers of coating material, at least one layer of the one or more layers of coating material may include an open matrix coating, the open matrix coating may include one or more active ingredients, the open matrix coating may include one or more polymers and one or more active ingredients, etc.).
    Type: Grant
    Filed: December 22, 2014
    Date of Patent: May 9, 2017
    Assignees: REGENTS OF THE UNIVERSITY OF MINNESOTA, NANOCOPOEIA, INC.
    Inventors: Robert A. Hoerr, Da-Ren Chen, John V. Carlson, David Y. H. Pui
  • Publication number: 20160235677
    Abstract: A method of converting a poorly water soluble crystalline compound to an amorphous compound and a method of increasing the solubility of a poorly water soluble crystalline compound in biorelevant fluid at pH 6.5 is disclosed. The method includes dissolving the compound and a polymer in a solvent to form a solution, the polymer being present in the solution in an amount such that after electrospraying the solution the compound is in an amorphous form, electrospraying the solution using an electrospray system, the electrospraying forming nanoparticles, collecting the nanoparticles on a substrate, and removing the nanoparticles in the form of a powder.
    Type: Application
    Filed: November 25, 2015
    Publication date: August 18, 2016
    Inventors: Robert A. Hoerr, Huijing Fu, James E. Lasch, Mourad F. Rahi
  • Publication number: 20160038968
    Abstract: A nanoparticle coated hydrogel may be formed by a method of electrospraying nanoparticles on to a surface includes providing a drug and polymer combination in solvent to an inner capillary of a coaxial dual capillary spray nozzle. A coating with a drug that releases over time may be provided. Open and closed matrixes may be selectively formed to help modify time release periods.
    Type: Application
    Filed: August 14, 2015
    Publication date: February 11, 2016
    Inventors: Robert A. Hoerr, John V. Carlson
  • Patent number: 9248217
    Abstract: A nanoparticle coated hydrogel may be formed by a method of electrospraying nanoparticles on to a hydrogel surface includes providing a drug and polymer combination in solvent to an inner capillary of a coaxial capillary spray nozzle. A coating with a drug that releases over time may be provided. Open and closed matrixes may be selectively formed to help modify time release periods.
    Type: Grant
    Filed: January 31, 2007
    Date of Patent: February 2, 2016
    Assignee: Nanocopocia, LLC
    Inventors: Robert A. Hoerr, John V. Carlson
  • Publication number: 20150352592
    Abstract: Devices to deliver one or more active ingredients for medical treatment may include a body of material presenting a surface including a polymer adapted to be rendered conductive such that one or more layers of electrospray particles are formable thereon or a body of conductive material presenting a surface upon which one or more layers of electrospray particles are formable thereon. A coating formed of electrospray particles may be deposited to adhere on the surface of the body of material (e.g., the coating may include one or more layers of coating material, at least one layer of the one or more layers of coating material may include an open matrix coating, the open matrix coating may include one or more active ingredients, the open matrix coating may include one or more polymers and one or more active ingredients, etc.).
    Type: Application
    Filed: December 22, 2014
    Publication date: December 10, 2015
    Inventors: ROBERT A. HOERR, DA-REN CHEN, JOHN V. CARLSON, DAVID Y.H. PUI
  • Patent number: 9108217
    Abstract: A nanoparticle coated hydrogel may be formed by a method of electrospraying nanoparticles on to a surface includes providing a drug and polymer combination in solvent to an inner capillary of a coaxial dual capillary spray nozzle. A coating with a drug that releases over time may be provided. Open and closed matrixes may be selectively formed to help modify time release periods.
    Type: Grant
    Filed: January 31, 2008
    Date of Patent: August 18, 2015
    Assignee: Nanocopoeia, Inc.
    Inventors: Robert A. Hoerr, John V. Carlson
  • Publication number: 20150158051
    Abstract: A nanoparticle coated hydrogel may be formed by a method of electrospraying nanoparticles on to a surface includes providing a drug and polymer combination in solvent to an inner capillary of a coaxial dual capillary spray nozzle. A coating with a drug that releases over time may be provided. Open and closed matrixes may be selectively formed to help modify time release periods.
    Type: Application
    Filed: January 31, 2008
    Publication date: June 11, 2015
    Applicant: Nanocopoeia, Inc.
    Inventors: Robert A. Hoerr, John V. Carlson
  • Publication number: 20130323403
    Abstract: Electrospray methods and systems for coating of objects (e.g., medical devices such as a stent structure) with selected types of coatings (e.g., open matrix coating and closed film coating).
    Type: Application
    Filed: May 24, 2013
    Publication date: December 5, 2013
    Applicants: REGENTS OF THE UNIVERSITY OF MINNESOTA, NANOCOPOEIA, INC.
    Inventors: ROBERT A. HOERR, DA-REN CHEN, JOHN V. CARLSON, DAVID Y.H. PUI
  • Publication number: 20120183960
    Abstract: A method of identifying an M17 strain of E. coli in a human biological sample is provided. The method comprises analyzing products of an amplification reaction using DNA extracted from the human biological sample and a primer pair which amplifies an M17 specific nucleic acid sequence of an M17 nucleic acid sequence, wherein the primer pair is selected from the group consisting of SEQ ID NOs: 37 and 38; SEQ ID NO: 39 and 40; and SEQ ID NOs: 45 and 46, wherein a product of the amplification reaction is indicative of an M17 strain of E. coli. Additional primers and kits comprising same are also provided.
    Type: Application
    Filed: December 7, 2011
    Publication date: July 19, 2012
    Applicant: Enterologics, Inc.
    Inventors: Robert A. HOERR, Eileen F. Bostwick, Douglas Testa
  • Publication number: 20110229627
    Abstract: Electrospray methods and systems for coating of objects (e.g., medical devices such as a stent structure) with selected types of coatings (e.g.
    Type: Application
    Filed: May 27, 2011
    Publication date: September 22, 2011
    Applicants: NANOCOPOEIA, INC., Regents of the University of Minnesota
    Inventors: ROBERT A. HOERR, JOHN V. CARLSON, DA-REN CHEN, DAVID Y.H. PUI
  • Patent number: 7951428
    Abstract: Electrospray methods and systems for coating of objects (e.g., medical devices such as a stent structure) with an open matrix coating. The open matrix coating is formed by electrospray using one or more nozzle structures each having at least an inner and outer opening. A first flow of a liquid spray composition is provided to the inner opening and a second flow of a liquid diluent composition is provided to the outer opening (e.g., the liquid diluent composition including at least one solvent, such as a composition having a dielectric constant equal to or greater than 10).
    Type: Grant
    Filed: January 31, 2007
    Date of Patent: May 31, 2011
    Assignee: Regents of the University of Minnesota
    Inventors: Robert A. Hoerr, John V. Carlson, Da-Ren Chen, David Y. H. Pui
  • Publication number: 20100310653
    Abstract: The present invention relates to the use of an extract made of leaves of Ginkgo biloba for the production of a preparation, or an extract made of leaves of Ginkgo biloba as an agent for the treatment and prophylaxis of the dementia syndrome, the early stages and pre-stages thereof, wherein 180 to 300 mg of Ginkgo extract is administered once a day.
    Type: Application
    Filed: December 18, 2008
    Publication date: December 9, 2010
    Applicant: DR. WILLMAR SCHWABE GMBH & CO. KG
    Inventors: Joachim Herrmann, Robert Hörr
  • Publication number: 20090252708
    Abstract: Biotherapeutic compositions of a non-pathogenic bacterial strain such as M-17 and its substrains and an anaerobic bacterial antibiotic such as metronidazole, are disclosed. Further disclosed are uses of M-17 or its substrains and an anaerobic bacterial antibiotic for treating disorders caused by anaerobic bacteria, whereby such disorders include, for example, pouchitis, microbial infection, irritable bowel syndrome, inflammatory bowel disease, mucous colitis and diarrhea.
    Type: Application
    Filed: May 17, 2007
    Publication date: October 8, 2009
    Applicant: Biobalance LLC
    Inventors: Leo Fitzpatrick, Robert A. Hoerr, Eileen F. Bostwick
  • Publication number: 20070278103
    Abstract: A nanoparticle coated hydrogel may be formed by a method of electrospraying nanoparticles on to a hydrogel surface includes providing a drug and polymer combination in solvent to an inner capillary of a coaxial capillary spray nozzle. A coating with a drug that releases over time may be provided. Open and closed matrixes may be selectively formed to help modify time release periods.
    Type: Application
    Filed: January 31, 2007
    Publication date: December 6, 2007
    Applicant: Nanocopoeia, Inc.
    Inventors: Robert Hoerr, John Carlson
  • Publication number: 20070199824
    Abstract: Electrospray methods and systems for coating of objects (e.g., medical devices such as a stent structure) with selected types of coatings (e.g.
    Type: Application
    Filed: January 31, 2007
    Publication date: August 30, 2007
    Inventors: Robert Hoerr, John Carlson, Da-Ren Chen, David Pui
  • Patent number: 5773000
    Abstract: The effective treatment of Clostridium difficile associated diseases, such as Clostridium difficile colitis, pseudomembranous colitis and antibiotic associated diarrhea, by administering an antibody having specific activity against Clostridium difficile colitis and toxins thereof alone or in combination with vancomycin, bacitracin or metronidazole is herein described as well as pharmaceutical compositions therefor.
    Type: Grant
    Filed: October 15, 1996
    Date of Patent: June 30, 1998
    Assignee: GalaGen Inc.
    Inventors: Eileen F. Bostwick, Robert A. Hoerr