Patents by Inventor Robert Hoerr
Robert Hoerr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20190193109Abstract: A nanoparticle coated hydrogel may be formed by a method of electrospraying nanoparticles on to a surface includes providing a drug and polymer combination in solvent to an inner capillary of a coaxial dual capillary spray nozzle. A coating with a drug that releases over time may be provided. Open and closed matrixes may be selectively formed to help modify time release periods.Type: ApplicationFiled: March 1, 2019Publication date: June 27, 2019Inventors: Robert A. Hoerr, John V. Carlson
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Patent number: 10252289Abstract: A nanoparticle coated hydrogel may be formed by a method of electrospraying nanoparticles on to a surface includes providing a drug and polymer combination in solvent to an inner capillary of a coaxial dual capillary spray nozzle. A coating with a drug that releases over time may be provided. Open and closed matrixes may be selectively formed to help modify time release periods.Type: GrantFiled: August 14, 2015Date of Patent: April 9, 2019Assignee: NANOCOPOEIA, INC.Inventors: Robert A. Hoerr, John V. Carlson
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Patent number: 9642694Abstract: Devices to deliver one or more active ingredients for medical treatment may include a body of material presenting a surface including a polymer adapted to be rendered conductive such that one or more layers of electrospray particles are formable thereon or a body of conductive material presenting a surface upon which one or more layers of electrospray particles are formable thereon. A coating formed of electrospray particles may be deposited to adhere on the surface of the body of material (e.g., the coating may include one or more layers of coating material, at least one layer of the one or more layers of coating material may include an open matrix coating, the open matrix coating may include one or more active ingredients, the open matrix coating may include one or more polymers and one or more active ingredients, etc.).Type: GrantFiled: December 22, 2014Date of Patent: May 9, 2017Assignees: REGENTS OF THE UNIVERSITY OF MINNESOTA, NANOCOPOEIA, INC.Inventors: Robert A. Hoerr, Da-Ren Chen, John V. Carlson, David Y. H. Pui
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Publication number: 20160235677Abstract: A method of converting a poorly water soluble crystalline compound to an amorphous compound and a method of increasing the solubility of a poorly water soluble crystalline compound in biorelevant fluid at pH 6.5 is disclosed. The method includes dissolving the compound and a polymer in a solvent to form a solution, the polymer being present in the solution in an amount such that after electrospraying the solution the compound is in an amorphous form, electrospraying the solution using an electrospray system, the electrospraying forming nanoparticles, collecting the nanoparticles on a substrate, and removing the nanoparticles in the form of a powder.Type: ApplicationFiled: November 25, 2015Publication date: August 18, 2016Inventors: Robert A. Hoerr, Huijing Fu, James E. Lasch, Mourad F. Rahi
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Publication number: 20160038968Abstract: A nanoparticle coated hydrogel may be formed by a method of electrospraying nanoparticles on to a surface includes providing a drug and polymer combination in solvent to an inner capillary of a coaxial dual capillary spray nozzle. A coating with a drug that releases over time may be provided. Open and closed matrixes may be selectively formed to help modify time release periods.Type: ApplicationFiled: August 14, 2015Publication date: February 11, 2016Inventors: Robert A. Hoerr, John V. Carlson
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Patent number: 9248217Abstract: A nanoparticle coated hydrogel may be formed by a method of electrospraying nanoparticles on to a hydrogel surface includes providing a drug and polymer combination in solvent to an inner capillary of a coaxial capillary spray nozzle. A coating with a drug that releases over time may be provided. Open and closed matrixes may be selectively formed to help modify time release periods.Type: GrantFiled: January 31, 2007Date of Patent: February 2, 2016Assignee: Nanocopocia, LLCInventors: Robert A. Hoerr, John V. Carlson
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Publication number: 20150352592Abstract: Devices to deliver one or more active ingredients for medical treatment may include a body of material presenting a surface including a polymer adapted to be rendered conductive such that one or more layers of electrospray particles are formable thereon or a body of conductive material presenting a surface upon which one or more layers of electrospray particles are formable thereon. A coating formed of electrospray particles may be deposited to adhere on the surface of the body of material (e.g., the coating may include one or more layers of coating material, at least one layer of the one or more layers of coating material may include an open matrix coating, the open matrix coating may include one or more active ingredients, the open matrix coating may include one or more polymers and one or more active ingredients, etc.).Type: ApplicationFiled: December 22, 2014Publication date: December 10, 2015Inventors: ROBERT A. HOERR, DA-REN CHEN, JOHN V. CARLSON, DAVID Y.H. PUI
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Patent number: 9108217Abstract: A nanoparticle coated hydrogel may be formed by a method of electrospraying nanoparticles on to a surface includes providing a drug and polymer combination in solvent to an inner capillary of a coaxial dual capillary spray nozzle. A coating with a drug that releases over time may be provided. Open and closed matrixes may be selectively formed to help modify time release periods.Type: GrantFiled: January 31, 2008Date of Patent: August 18, 2015Assignee: Nanocopoeia, Inc.Inventors: Robert A. Hoerr, John V. Carlson
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Publication number: 20150158051Abstract: A nanoparticle coated hydrogel may be formed by a method of electrospraying nanoparticles on to a surface includes providing a drug and polymer combination in solvent to an inner capillary of a coaxial dual capillary spray nozzle. A coating with a drug that releases over time may be provided. Open and closed matrixes may be selectively formed to help modify time release periods.Type: ApplicationFiled: January 31, 2008Publication date: June 11, 2015Applicant: Nanocopoeia, Inc.Inventors: Robert A. Hoerr, John V. Carlson
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Publication number: 20130323403Abstract: Electrospray methods and systems for coating of objects (e.g., medical devices such as a stent structure) with selected types of coatings (e.g., open matrix coating and closed film coating).Type: ApplicationFiled: May 24, 2013Publication date: December 5, 2013Applicants: REGENTS OF THE UNIVERSITY OF MINNESOTA, NANOCOPOEIA, INC.Inventors: ROBERT A. HOERR, DA-REN CHEN, JOHN V. CARLSON, DAVID Y.H. PUI
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Publication number: 20120183960Abstract: A method of identifying an M17 strain of E. coli in a human biological sample is provided. The method comprises analyzing products of an amplification reaction using DNA extracted from the human biological sample and a primer pair which amplifies an M17 specific nucleic acid sequence of an M17 nucleic acid sequence, wherein the primer pair is selected from the group consisting of SEQ ID NOs: 37 and 38; SEQ ID NO: 39 and 40; and SEQ ID NOs: 45 and 46, wherein a product of the amplification reaction is indicative of an M17 strain of E. coli. Additional primers and kits comprising same are also provided.Type: ApplicationFiled: December 7, 2011Publication date: July 19, 2012Applicant: Enterologics, Inc.Inventors: Robert A. HOERR, Eileen F. Bostwick, Douglas Testa
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Publication number: 20110229627Abstract: Electrospray methods and systems for coating of objects (e.g., medical devices such as a stent structure) with selected types of coatings (e.g.Type: ApplicationFiled: May 27, 2011Publication date: September 22, 2011Applicants: NANOCOPOEIA, INC., Regents of the University of MinnesotaInventors: ROBERT A. HOERR, JOHN V. CARLSON, DA-REN CHEN, DAVID Y.H. PUI
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Patent number: 7951428Abstract: Electrospray methods and systems for coating of objects (e.g., medical devices such as a stent structure) with an open matrix coating. The open matrix coating is formed by electrospray using one or more nozzle structures each having at least an inner and outer opening. A first flow of a liquid spray composition is provided to the inner opening and a second flow of a liquid diluent composition is provided to the outer opening (e.g., the liquid diluent composition including at least one solvent, such as a composition having a dielectric constant equal to or greater than 10).Type: GrantFiled: January 31, 2007Date of Patent: May 31, 2011Assignee: Regents of the University of MinnesotaInventors: Robert A. Hoerr, John V. Carlson, Da-Ren Chen, David Y. H. Pui
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Publication number: 20100310653Abstract: The present invention relates to the use of an extract made of leaves of Ginkgo biloba for the production of a preparation, or an extract made of leaves of Ginkgo biloba as an agent for the treatment and prophylaxis of the dementia syndrome, the early stages and pre-stages thereof, wherein 180 to 300 mg of Ginkgo extract is administered once a day.Type: ApplicationFiled: December 18, 2008Publication date: December 9, 2010Applicant: DR. WILLMAR SCHWABE GMBH & CO. KGInventors: Joachim Herrmann, Robert Hörr
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Publication number: 20090252708Abstract: Biotherapeutic compositions of a non-pathogenic bacterial strain such as M-17 and its substrains and an anaerobic bacterial antibiotic such as metronidazole, are disclosed. Further disclosed are uses of M-17 or its substrains and an anaerobic bacterial antibiotic for treating disorders caused by anaerobic bacteria, whereby such disorders include, for example, pouchitis, microbial infection, irritable bowel syndrome, inflammatory bowel disease, mucous colitis and diarrhea.Type: ApplicationFiled: May 17, 2007Publication date: October 8, 2009Applicant: Biobalance LLCInventors: Leo Fitzpatrick, Robert A. Hoerr, Eileen F. Bostwick
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Publication number: 20070278103Abstract: A nanoparticle coated hydrogel may be formed by a method of electrospraying nanoparticles on to a hydrogel surface includes providing a drug and polymer combination in solvent to an inner capillary of a coaxial capillary spray nozzle. A coating with a drug that releases over time may be provided. Open and closed matrixes may be selectively formed to help modify time release periods.Type: ApplicationFiled: January 31, 2007Publication date: December 6, 2007Applicant: Nanocopoeia, Inc.Inventors: Robert Hoerr, John Carlson
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Publication number: 20070199824Abstract: Electrospray methods and systems for coating of objects (e.g., medical devices such as a stent structure) with selected types of coatings (e.g.Type: ApplicationFiled: January 31, 2007Publication date: August 30, 2007Inventors: Robert Hoerr, John Carlson, Da-Ren Chen, David Pui
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Patent number: 5773000Abstract: The effective treatment of Clostridium difficile associated diseases, such as Clostridium difficile colitis, pseudomembranous colitis and antibiotic associated diarrhea, by administering an antibody having specific activity against Clostridium difficile colitis and toxins thereof alone or in combination with vancomycin, bacitracin or metronidazole is herein described as well as pharmaceutical compositions therefor.Type: GrantFiled: October 15, 1996Date of Patent: June 30, 1998Assignee: GalaGen Inc.Inventors: Eileen F. Bostwick, Robert A. Hoerr