Abstract: A vehicle entertainment system is for use with wireless headphones, with each wireless headphone being operable via a respective paired wireless connection. The vehicle entertainment system may include video entertainment displays for a vehicle, and a controller for the vehicle. The controller may be configured to establish respective paired wireless connections with the wireless headphones, and provide selectable access to a plurality of different audio/video (A/V) entertainment content streams. Each of the A/V entertainment content streams may include a respective video entertainment stream and an associated audio entertainment stream. The controller may be further configured to send selected video entertainment content streams for viewing at the video entertainment displays, and send selected audio entertainment content streams over the respective paired wireless connections for hearing at the wireless headphones.

Abstract: A vehicle entertainment system is for use with wireless headphones, with each wireless headphone being operable via a respective paired wireless connection. The vehicle entertainment system may include video entertainment displays for a vehicle, and a controller for the vehicle. The controller may be configured to establish respective paired wireless connections with the wireless headphones, and provide selectable access to a plurality of different audio/video (A/V) entertainment content streams. Each of the A/V entertainment content streams may include a respective video entertainment stream and an associated audio entertainment stream. The controller may be further configured to send selected video entertainment content streams for viewing at the video entertainment displays, and send selected audio entertainment content streams over the respective paired wireless connections for hearing at the wireless headphones.

Abstract: Taxanes having an ester substituent at C(7), a hydroxy substituent at C(10), and a range of C(2), C(9), C(14), and side chain substituents.

Abstract: Taxanes having a heterosubstituted acetate substituent at C(10), a hydroxy substituent at C(7), and a range of C(2), C(9), C(14), and side chain substituents.

Abstract: The present invention provides processes for the production of docetaxel. Docetaxel is produced by protecting the C(7) and the C(10) hydroxy groups of 10-DAB with a bridging silicon-based protecting group. The resulting 7,10-protected 10-DAB derivative is then derivatized and deprotected to form docetaxel.

Abstract: A new process for resolution of an enantiomeric mixture of C3-hydroxyl substituted ?-lactams is disclosed. Generally, the enantiomeric mixture is treated with an optically active proline acylating agent to form a C3-ester substituted ?-lactam diastereomer or a mixture of C3-ester substituted ?-lactam diastereomers followed by selective recovery of the unreacted enantiomer or of one of the diastereomers.

Abstract: The present invention provides processes for the production of polycyclic fused ring compounds. The polycyclic fused ring compounds are produced by protecting a polycyclic fused ring polyol with a bridging silicon-based protecting group and attaching a suitable side chain. Novel polycyclic fused ring compounds and intermediate compounds are also described.

Abstract: The present invention is directed to a process for the preparation of ?-lactams. Generally, an imine is cyclocondensed with a ketene acetal or enolate to form the ?-lactam product in a “one pot” synthesis, this process is generally performed at a higher temperature than conventional processes.

Abstract: The present invention provides processes for the production of paclitaxel. Paclitaxel is produced by protecting the C(7) and the C(10) hydroxy groups of 10-DAB with a bridging silicon-based protecting group. The resulting 7,10-protected 10-DAB derivative is then derivatized and deprotected to form paclitaxel.

Abstract: Compositions comprising a taxane having a cyclopropyl ester substituent at C10, a keto substituent at C9, a hydroxy substituent at C7, a 2-furyl substituent at C3? and an isobutoxycarbamate substituent at C3?.

Abstract: Taxanes having a methylcarbonate or ethylcarbonate substituent at C(10), a hydroxy substituent at C(7), and a range of C(13) side chain substituents.

Abstract: Processes for the preparation of taxol and other taxanes through selective derivatization of the C(7) hydroxyl and C(10) hydroxyl groups of 10-DAB, particularly a novel process using a new strategy in which the C(10) hydroxyl group is protected or derivatized prior to the C(7) hydroxyl group; and the provision of C(7) and C(10) derivatized 10-DAB compounds.

Abstract: A taxane having a cyclopentyl ester substituent at C10, a keto substituent at C9, a hydroxy substituent at C2, a 2-thienyl substituent at C3? and an isopropoxycarbamate substituent at C3?.

Abstract: A taxane having the formula: wherein X3 is furyl, X5 is t-butoxycarbonyl, Bz is benzoyl, and Ac is acetyl.

Abstract: Compositions comprising a taxane having a carbamoyloxy substituent at C(10), a hydroxy substituent at C(7), and a range of C(2), C(9), C(14), and side chain substituents.

Abstract: Taxanes having a carbonate substituent at C(7), a hydroxy substituent at C(10), and a range of C(2), C(9), C(14), and side chain substituents.

Abstract: Texanes having a heterosubstituted acetate substituent at C(7), a hydroxy substitutent at C(10), and a range of C(2), C(9), C(14), and side chain substituents.

Abstract: Compositions comprising a taxane having a heterosubstituted acetate substituent at C(10), a hydroxy substituent at C(7), and a range of C(2), C(9), C(14), and side chain substituents.

Abstract: Taxanes having a carbamoyloxy substituent at C(7), a hydroxy substituent at C(10, and a range of C(2), C(9), C(14), and side chain substituents.