Patents by Inventor Robert Hondal

Robert Hondal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treatment comprising Selenoprotein P fragment-containing compounds
    Patent number: 11878997
    Abstract: This invention relates to methods of administering compounds containing selenium, selenocysteine, or a selenocysteine peptide to treat, for example, conditions associated with selenium deficiency, or ferroptoptic, parthanototic, and endoplasmic reticulum stress, and/or cancer. The methods of treatment may activate or inhibit (via TFAP2C and Sp1 proteins) the adaptive homeostatic response of the selenome. The compounds may contain a targeting sequence that causes them to be delivered to specific organs and/or tissues. The compounds may be administered, for example, orally, intranasally, intravenously, or by a minimally invasive catheter or BrainPath.
    Type: Grant
    Filed: June 30, 2021
    Date of Patent: January 23, 2024
    Assignees: Burke Neurological Institute, University of Vermont and State Agricultural College
    Inventors: Rajiv R. Ratan, Ishraq Alim, Saravanan Karuppagounder, Robert Hondal