Abstract: A sanitary pressure relief device which includes a rigid sleeve having an annular resilient collar secured to one end thereof, as by a ring clamp. This resilient collar is adapted to be clampingly and sealingly engaged around the end of a cleanout fitting, as by a further ring clamp. An elongated resilient glove is clampingly and sealingly engaged to the other end of the sleeve, as by a further ring clamp, which glove permits removal of a screw plug from the cleanout fitting. The sleeve has a discharge opening formed in the sidewall thereof, and a length of hose is connected to this discharge opening. A suitable valve or clamp is associated with the hose for opening and closing same, to permit the controlled discharge of liquid from a drain pipe.