Patents by Inventor Robert Hyde
Robert Hyde has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11978976Abstract: A removable cable connector engages with an electronic device such that the removable cable connector removably yet securely attaches to the electronic device. In some embodiments, the electronic device includes a plate configured to guide an electronic plug of the removable cable connector toward an electronic receptacle of the electronic device. The plate may be further configured to include one or more locators for holding the electronic receptacle of the electronic device in place. The removable cable connector may include a molded housing formed using a two-shot overmolding process to form a first overmolded strain relief portion and a second overmolded strain relief portion which cover fasteners that fasten a face plate to the connector.Type: GrantFiled: June 29, 2021Date of Patent: May 7, 2024Assignee: BFLY OPERATIONS, INC.Inventors: Robert Schneider, Adam Mekeel Mack, Ryan Silvestri, Timothy A. Hyde, Jason Fischman
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Publication number: 20240081777Abstract: Ergonomic attachments for a handheld ultrasound probe are described herein. An attachment assembly includes a plate-shaped member that includes a passage configured to accommodate the handheld ultrasound probe such that when the plate-shaped member is inserted in the attachment assembly, a portion of a transducer head of the handheld ultrasound probe protrudes from the plate-shaped member. Another attachment assembly includes a shell that attaches to the handheld ultrasound probe and partially covers the handheld ultrasound probe, and strap anchors that are each connected to the shell and are disposed at opposite ends of the shell. Another attachment includes a curved bar that is continuous between a proximal attachment flange, of the curved bar, that attaches to a first location of the handheld ultrasound probe and a distal attachment flange, of the curved bar, that attaches to a second location of the handheld ultrasound probe.Type: ApplicationFiled: September 13, 2023Publication date: March 14, 2024Applicant: BFLY OPERATIONS, INC.Inventors: John Caswell, Timothy Hyde, Jason Fischman, Scott Rumschlag, Robert Schneider
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Patent number: 11913936Abstract: An apparatus for supporting an array of layers of amphiphilic molecules, the apparatus comprising: a body, formed in a surface of the body, an array of sensor wells capable of supporting a layer of amphiphilic molecules across the sensor wells, the sensor wells each containing an electrode for connection to an electrical circuit, and formed in the surface of the body between the sensor wells, flow control wells capable of smoothing the flow of a fluid across the surface.Type: GrantFiled: December 20, 2022Date of Patent: February 27, 2024Assignee: Oxford Nanopore Technologies PLCInventors: Jason Robert Hyde, James Anthony Clarke, Gaëlle Anne-Leonie Andreatta
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Publication number: 20230228732Abstract: There is disclosed a nanopore support structure comprising a wall layer comprising walls defining a plurality of wells, and overhangs extending from the walls across each of the wells, the overhang defining an aperture configured to support a membrane suitable for insertion of a nanopore. There is further disclosed a nanopore sensing device comprising a nanopore support structure, and methods of manufacturing the nanopore support structure and the nanopore sensing device.Type: ApplicationFiled: April 29, 2021Publication date: July 20, 2023Applicant: Oxford Nanopore Technologies PLCInventors: Ping Xie, Justin Millis, Ken Healy, James Anthony Clarke, Jason Robert Hyde, Richard Kenneth John Wiltshire, Jonathan Edward McKendry, Robert Greasty, Clive Gavin Brown, loana Pera, Gurdial Singh Sanghera, Mark Hyland, Pedro Miguel Ortiz Bahamon, Mark David Jackson, Paul Raymond Mackett, Rhodri Rhys Davies
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Publication number: 20230228733Abstract: An apparatus for supporting an array of layers of amphiphilic molecules, the apparatus comprising: a body, formed in a surface of the body, an array of sensor wells capable of supporting a layer of amphiphilic molecules across the sensor wells, the sensor wells each containing an electrode for connection to an electrical circuit, and formed in the surface of the body between the sensor wells, flow control wells capable of smoothing the flow of a fluid across the surface.Type: ApplicationFiled: December 20, 2022Publication date: July 20, 2023Applicant: Oxford Nanopore Technologies PLCInventors: Jason Robert Hyde, James Anthony Clarke, Gaëlle Anne-Leonie Andreatta
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Publication number: 20230158503Abstract: Droplet interfaces are formed between droplets in an electro-wetting device comprising an array of actuation electrodes. Actuation signals are applied to selected actuation electrodes to place the droplets into an energised state in which the shape of the droplets is modified compared to a shape of the droplets in a lower energy state and to bring the two droplets into proximity. The actuation signals are then changed to lower the energy of the droplets into the lower energy state so that the droplets relax into the gap and the two droplets contact each other thereby forming a droplet interface. The use of sensing electrodes in the device permit electrical current measurements across the droplet interface. The sensing electrodes can be used for either (i) applying a reference signal during droplet actuation or (ii) recording electrical current measurements.Type: ApplicationFiled: November 18, 2022Publication date: May 25, 2023Applicants: Oxford Nanopore Technologies PLC, Sharp Life Science EU (Ltd)Inventors: Matthew Holden, James White, Andrew John Heron, James Anthony Clarke, Jason Robert Hyde, Benjamin James Hadwen, Sally Anderson
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Publication number: 20230041418Abstract: Provided herein is a method of concentrating a tethering complex in a region of an amphiphilic layer, such as a lipid membrane. Also provided herein are methods of assembling a tethering complex; methods of concentrating an analyte in the region of a detector; amphiphilic layers; and arrays and devices for use in the disclosed methods.Type: ApplicationFiled: December 3, 2020Publication date: February 9, 2023Applicant: Oxford Nanopore Technologies PLCInventors: Clive Gavin Brown, Andrew John Heron, James Anthony Clarke, Paul Richard Moody, Aaron Luke Acton, Jason Robert Hyde
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Patent number: 11561216Abstract: An apparatus for supporting an array of layers of amphiphilic molecules, the apparatus comprising: a body, formed in a surface of the body, an array of sensor wells capable of supporting a layer of amphiphilic molecules across the sensor wells, the sensor wells each containing an electrode for connection to an electrical circuit, and formed in the surface of the body between the sensor wells, flow control wells capable of smoothing the flow of a fluid across the surface.Type: GrantFiled: May 6, 2019Date of Patent: January 24, 2023Assignee: Oxford Nanopore Technologies PLCInventors: Jason Robert Hyde, James Anthony Clarke, Gaëlle Anne-Leonie Andreatta
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Patent number: 11534763Abstract: Droplet interfaces are formed between droplets in an electro-wetting device comprising an array of actuation electrodes. Actuation signals are applied to selected actuation electrodes to place the droplets into an energised state in which the shape of the droplets is modified compared to a shape of the droplets in a lower energy state and to bring the two droplets into proximity. The actuation signals are then changed to lower the energy of the droplets into the lower energy state so that the droplets relax into the gap and the two droplets contact each other thereby forming a droplet interface. The use of sensing electrodes in the device permit electrical current measurements across the droplet interface. The sensing electrodes can be used for either (i) applying a reference signal during droplet actuation or (ii) recording electrical current measurements.Type: GrantFiled: December 21, 2018Date of Patent: December 27, 2022Assignees: Oxford Nanopore Technologies PLC, Sharp Life Science EU (Ltd)Inventors: Matthew Holden, James White, Andrew John Heron, James Anthony Clarke, Jason Robert Hyde, Benjamin James Hadwen, Sally Anderson
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Publication number: 20220396013Abstract: The invention relates to a method of forming a sensing device for supporting a plurality of nanopores upon an array of wells. The method involves providing a substrate, said substrate having a surface having an array of electrodes located thereon for connecting to or for configuring upon an electronic circuit. Separately, a well array structure is provided, which has an array of walls defining through-holes for defining wells. The substrate and well array structures are aligning said array of electrodes define, at least in part, a portion of the bases of respective wells at the bottom of the through holes. The resulting sensing device overcomes problems with known sensing devices by employing a substrate and/or well array structure, or hybrid thereof, that employs alternative materials or manufacturing processes.Type: ApplicationFiled: October 23, 2020Publication date: December 15, 2022Applicant: Oxford Nanopore Technologies PLCInventors: Pedro Miguel Ortiz Bahamon, Paul Raymond Mackett, Robert Greasty, Jonathan Edward McKendry, Jason Robert Hyde, Mark David Jackson, Richard Kenneth John Wiltshire, Rhodri Rhys Davies, Mark Hyland, James Anthony Clarke, Gurdial Singh Sanghera
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Publication number: 20220023819Abstract: An array of membranes comprising amphipathic molecules is formed using an apparatus comprising a support defining an array of compartments. Volumes comprising polar medium are provided within respective compartments and a layer comprising apolar medium is provided extending across the openings with the volumes. Polar medium is flowed across the support to displace apolar medium and form a layer in contact with the volumes, forming membranes comprising amphipathic molecules at the interfaces. In one construction of the apparatus, the support that comprises partitions which comprise inner portions and outer portions. The inner portions define inner recesses without gaps therebetween that are capable of constraining the volumes comprising polar medium contained in neighbouring inner recesses from contacting each other. The outer portions extend outwardly from the inner portions and have gaps allowing the flow of an apolar medium across the substrate.Type: ApplicationFiled: July 1, 2021Publication date: January 27, 2022Applicant: Oxford Nanopore Technologies Ltd.Inventors: Jason Robert Hyde, Pedro Miguel Ortiz Bahamon, Clive Gavin Brown, Andrew John, Paul Raymond Mackett
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Patent number: 11084015Abstract: An array of membranes comprising amphipathic molecules is formed using an apparatus comprising a support defining an array of compartments. Volumes comprising polar medium are provided within respective compartments and a layer comprising apolar medium is provided extending across the openings with the volumes. Polar medium is flowed across the support to displace apolar medium and form a layer in contact with the volumes, forming membranes comprising amphipathic molecules at the interfaces. In one construction of the apparatus, the support that comprises partitions which comprise inner portions and outer portions. The inner portions define inner recesses without gaps therebetween that are capable of constraining the volumes comprising polar medium contained in neighbouring inner recesses from contacting each other. The outer portions extend outwardly from the inner portions and have gaps allowing the flow of an apolar medium across the substrate.Type: GrantFiled: September 30, 2020Date of Patent: August 10, 2021Assignee: Oxford Nanopore Technologies Ltd.Inventors: Jason Robert Hyde, Pedro Miguel Ortiz Bahamon, Clive Gavin Brown, Andrew John Heron, Paul Raymond Mackett
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Publication number: 20210086160Abstract: An array of membranes comprising amphipathic molecules is formed using an apparatus comprising a support defining an array of compartments. Volumes comprising polar medium are provided within respective compartments and a layer comprising apolar medium is provided extending across the openings with the volumes. Polar medium is flowed across the support to displace apolar medium and form a layer in contact with the volumes, forming membranes comprising amphipathic molecules at the interfaces. In one construction of the apparatus, the support that comprises partitions which comprise inner portions and outer portions. The inner portions define inner recesses without gaps therebetween that are capable of constraining the volumes comprising polar medium contained in neighbouring inner recesses from contacting each other. The outer portions extend outwardly from the inner portions and have gaps allowing the flow of an apolar medium across the substrate.Type: ApplicationFiled: September 30, 2020Publication date: March 25, 2021Applicant: Oxford Nanopore Technologies Ltd.Inventors: Jason Robert Hyde, Pedro Miguel Ortiz Bahamon, Clive Gavin Brown, Andrew John Heron, Paul Raymond Mackett
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Publication number: 20210008557Abstract: Droplet interfaces are formed between droplets in an electro-wetting device comprising an array of actuation electrodes. Actuation signals are applied to selected actuation electrodes to place the droplets into an energised state in which the shape of the droplets is modified compared to a shape of the droplets in a lower energy state and to bring the two droplets into proximity. The actuation signals are then changed to lower the energy of the droplets into the lower energy state so that the droplets relax into the gap and the two droplets contact each other thereby forming a droplet interface. The use of sensing electrodes in the device permit electrical current measurements across the droplet interface. The sensing electrodes can be used for either (i) applying a reference signal during droplet actuation or (ii) recording electrical current measurements.Type: ApplicationFiled: December 21, 2018Publication date: January 14, 2021Applicants: Oxford Nanopore Technologies Ltd., Sharp Life Science (EU) LtdInventors: Matthew HOLDEN, James WHITE, Andrew John HERON, James Anthony CLARKE, Jason Robert HYDE, Benjamin James HADWEN, Sally ANDERSON
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Patent number: 10814298Abstract: An array of membranes comprising amphipathic molecules is formed using an apparatus comprising a support defining an array of compartments. Volumes comprising polar medium are provided within respective compartments and a layer comprising apolar medium is provided extending across the openings with the volumes. Polar medium is flowed across the support to displace apolar medium and form a layer in contact with the volumes, forming membranes comprising amphipathic molecules at the interfaces. In one construction of the apparatus, the support that comprises partitions which comprise inner portions and outer portions. The inner portions define inner recesses without gaps therebetween that are capable of constraining the volumes comprising polar medium contained in neighbouring inner recesses from contacting each other. The outer portions extend outwardly from the inner portions and have gaps allowing the flow of an apolar medium across the substrate.Type: GrantFiled: October 23, 2013Date of Patent: October 27, 2020Assignee: Oxford Nanopore Technologies Ltd.Inventors: Jason Robert Hyde, Pedro Miguel Ortiz Bahamon, Clive Gavin Brown, Andrew John Heron, Paul Raymond Mackett
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Patent number: 10549274Abstract: A detachable electrical device can be formed from a kit comprising a pair of component parts adapted for connection to each other, wherein the connected components of the device may be subsequently disconnected, comprising: an array of electrical connectors, each electrical connector comprising an electrically conductive liquid; and an array of electrodes; wherein the arrays can be brought into contact with each other so as to provide a plurality of electrical connections between the electrically conductive liquid of the array of electrical connectors and the electrodes of the array of electrodes, and wherein the electrical connections may be subsequently broken by detaching the electrically conductive liquid from the electrodes of the array.Type: GrantFiled: October 15, 2015Date of Patent: February 4, 2020Assignee: Oxford Nanopore Technologies Ltd.Inventors: Clive Gavin Brown, Jason Robert Hyde, Mark David Jackson, Paul Raymond Mackett, Jonathan Edward McKendry, Richard Kenneth John Wiltshire
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Publication number: 20190391128Abstract: An apparatus for supporting an array of layers of amphiphilic molecules, the apparatus comprising: a body, formed in a surface of the body, an array of sensor wells capable of supporting a layer of amphiphilic molecules across the sensor wells, the sensor wells each containing an electrode for connection to an electrical circuit, and formed in the surface of the body between the sensor wells, flow control wells capable of smoothing the flow of a fluid across the surface.Type: ApplicationFiled: May 6, 2019Publication date: December 26, 2019Applicant: Oxford Nanopore Technologies Ltd.Inventors: Jason Robert Hyde, James Anthony Clarke, Gaëlle Anne-Leonie Andreatta
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Patent number: 10338056Abstract: An apparatus for supporting an array of layers of amphiphilic molecules, the apparatus comprising: a body (11), formed in a surface of the body, an array of sensor wells (10) capable of supporting a layer of amphiphilic molecules (30) across the sensor wells, the sensor wells each containing an electrode (12) for connection to an electrical circuit, and formed in the surface of the body between the sensor wells, flow control wells capable of smoothing the flow of a fluid across the surface.Type: GrantFiled: February 13, 2013Date of Patent: July 2, 2019Assignee: Oxford Nanopore Technologies Ltd.Inventors: Jason Robert Hyde, James Anthony Clarke, Gaëlle Anne-Leonie Andreatta
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Patent number: 9823235Abstract: The invention provides a method of forming a membrane between a first volume of polar medium and a second volume of polar medium. In some embodiments, the method involves providing a first volume including polar medium and a second volume including polar medium which are separated from one another by an apolar medium, in which at least one of the first and second volumes has a layer including amphipathic molecules.Type: GrantFiled: October 23, 2013Date of Patent: November 21, 2017Assignee: Oxford Nanopre Technologies Ltd.Inventors: Andrew John Heron, Jason Robert Hyde, Clive Gavin Brown
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Patent number: D1020356Type: GrantFiled: June 30, 2021Date of Patent: April 2, 2024Assignee: Weber-Stephen Products LLCInventors: Robert Farmer, Cassandra A. S. McVey, Brian C. Donnelly, Christian Hyde, Michelle Stohl