Patents by Inventor Robert J. Altenbach

Robert J. Altenbach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Macrocyclic Benzofused Pyrimidine Derivatives
    Publication number: 20080188452
    Abstract: Macrocyclic benzofused pyrimidine compounds, compositions comprising such compounds, methods for making the compounds, and methods of treating and preventing the progression of diseases, conditions and disorders using such compounds and compositions are described herein.
    Type: Application
    Filed: September 28, 2007
    Publication date: August 7, 2008
    Inventors: Robert J. Altenbach, Huaqing Liu, Irene Drizin, Marlon D. Cowart, Neil Wishart, David J. Babinski, Robert J. Gregg, Arthur A. Hancock, Kathryn J. Hancock, Timothy A. Esbenshade, Gin C. Hsieh, Jorge D. Brioni, Marie P. Honore, Lawrence A. Black, Chen Zhao, Brian D. Wakefield
  • Tri- and bi-cyclic heteroaryl histamine-3 receptor ligands
    Patent number: 7205316
    Abstract: Compounds of formula (I) wherein R1 or R2 is a tricyclic or bicyclic ring, each of which contains at least two heteroatoms, and R1, R2, R3, R3a, R3b, R4, R5, L, X, X?, Y, Y?, Z, and Z? are as defined herein, are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions, and a process for preparing compounds within the scope of formula (I).
    Type: Grant
    Filed: May 6, 2005
    Date of Patent: April 17, 2007
    Assignee: Abbott Laboratories
    Inventors: Robert J. Altenbach, Lawrence A. Black, Marlon D. Cowart, Huaqing Liu
  • Bicyclic-substituted amines as histamine-3 receptor ligands
    Patent number: 7153889
    Abstract: Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions, and a process for preparing compounds within the scope of formula (I).
    Type: Grant
    Filed: October 22, 2003
    Date of Patent: December 26, 2006
    Assignee: Abbott Laboratories
    Inventors: Robert J. Altenbach, Lawrence A. Black, Sou-Jen Chang, Marlon D. Cowart, Ramin Faghih, Gregory A. Gfesser, Yi-Yin Ku, Huaqing Liu, Kirill A. Lukin, Diana L. Nersesian, Yu-ming Pu, Padam N. Sharma, Youssef L. Bennani, Michael P. Curtis
  • Bicyclic-substituted amines having cyclic-substituted monocyclic substituents
    Patent number: 7098222
    Abstract: Compounds of formula (I) wherein R1 or R2 is an aromatic or non-aromatic ring directly joined or joined by a linker, as represented by L2 and L3, to a heteroaromatic core, and X, X?, Y, Y?, Z, Z?, R1, R2, R3, R3a, R3b, R4, R5, L, L2, and L3 are as defined herein, are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions, and a process for preparing compounds within the scope of formula (I).
    Type: Grant
    Filed: May 6, 2005
    Date of Patent: August 29, 2006
    Assignee: Abbott Laboratories
    Inventors: Robert J. Altenbach, Lawrence A. Black, Sou-Jen Chang, Marlon D. Cowart, Ramin Faghih, Gregory A. Gfesser, Yi-Yin Ku, Huaqing Liu, Kirill A. Lukin, Diana L. Nersesian, Yu-ming Pu, Michael P. Curtis
  • Fused bicyclic-substituted amines as histamine-3 receptor ligands
    Patent number: 7094790
    Abstract: Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands and methods for using such compounds and compositions.
    Type: Grant
    Filed: April 30, 2004
    Date of Patent: August 22, 2006
    Assignee: Abbott Laboratories
    Inventors: Marlon D. Cowart, Yi-Yin Ku, Sou-Jen Chang, Dilinie P. Fernando, Timothy A. Grieme, Robert J. Altenbach
  • Fused bicyclic-substituted amines as histamine-3 receptor ligands
    Publication number: 20040248899
    Abstract: Compounds of formula (I) 1
    Type: Application
    Filed: April 30, 2004
    Publication date: December 9, 2004
    Inventors: Marlon D. Cowart, Yi-Yin Ku, Sou-Jen Chang, Dilinie P. Fernando, Timothy A. Grieme, Robert J. Altenbach
  • Fused bicyclic-substituted amines as histamine-3 receptor ligands
    Publication number: 20040224952
    Abstract: Compounds of formula (I) 1
    Type: Application
    Filed: May 7, 2003
    Publication date: November 11, 2004
    Inventors: Marlon D. Cowart, Yi-Yin Ku, Sou-Jen Chang, Dilinie P. Fernando, Timothy A. Grieme, Robert J. Altenbach
  • Fused bicyclic-substituted amines as histamine-3 receptor ligands
    Publication number: 20040224953
    Abstract: Compounds of formula (I) 1
    Type: Application
    Filed: September 25, 2003
    Publication date: November 11, 2004
    Inventors: Marlon D. Cowart, Yi-Yin Ku, Sou-Jen Chang, Dilinie P. Fernando, Timothy A. Grieme, Robert J. Altenbach
  • Tricyclic dihydropyrazolone and tricyclic dihydroisoxazolone potassium channel openers
    Patent number: 6780872
    Abstract: Compounds of formula I are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.
    Type: Grant
    Filed: January 22, 2003
    Date of Patent: August 24, 2004
    Assignee: Abbott Laboratories
    Inventors: Irene Drizin, Robert J. Altenbach, William A. Carroll
  • Bicyclic-substituted amines as histamine-3 receptor ligands
    Publication number: 20040152704
    Abstract: Compounds of formula (I) 1
    Type: Application
    Filed: October 22, 2003
    Publication date: August 5, 2004
    Inventors: Robert J. Altenbach, Lawrence A. Black, Sou-Jen Chang, Marlon D. Cowart, Ramin Faghih, Gregory A. Gfesser, Yi-Yin Ku, Huaqing Liu, Kirill A. Lukin, Diana L. Nersesian, Yu-ming Pu, Padam N. Sharma, Youssef L. Bennani, Michael P. Curtis
  • Bicyclic-substituted amines as histamine-3 receptor ligands
    Publication number: 20040092521
    Abstract: Compounds of formula (I) 1
    Type: Application
    Filed: November 12, 2002
    Publication date: May 13, 2004
    Inventors: Robert J. Altenbach, Lawrence A. Black, Sou-Jen Chang, Marlon D. Cowart, Ramin Faghih, Gregory A. Gfesser, Yi-yin Ku, Huaqing Liu, Kirill A. Lukin, Diana L. Nersesian, Yu-ming Pu, Padam N. Sharma, Youssef L. Bennani
  • Potassium channel openers
    Patent number: 6645968
    Abstract: Compounds of formula I: are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.
    Type: Grant
    Filed: February 5, 2001
    Date of Patent: November 11, 2003
    Assignee: Abbott Laboratories
    Inventors: Robert J. Altenbach, Hao Bai, Jorge D. Brioni, William A. Carroll, Murali Gopalakrishnan, Robert J. Gregg, Mark W. Holladay, Peggy P. Huang, John F. Kincaid, Michael E. Kort, Philip R. Kym, John K. Lynch, Arturo Perez-Medrano, Henry Q. Zhang
  • Pyrano, piperidino, and thiopyrano compounds and methods of use
    Patent number: 6642222
    Abstract: The present invention provides novel compounds of formula I which may be useful in hyperpolarizing cell membranes, opening potassium channels, relaxing smooth muscle cells, and inhibiting bladder contractions.
    Type: Grant
    Filed: May 3, 2000
    Date of Patent: November 4, 2003
    Assignee: Abbott Laboratories
    Inventors: William A. Carroll, Konstantinos A. Agrios, Robert J. Altenbach, Irene Drizin, Michael E. Kort
  • Radioligands and their use for identifying potassium channel modulators
    Patent number: 6632418
    Abstract: The present invention relates to novel radioligands and test methods using those radioligands in screening compounds.
    Type: Grant
    Filed: July 30, 2002
    Date of Patent: October 14, 2003
    Assignee: Abbott Laboratories
    Inventors: Robert J. Altenbach, Gary A. Rotert, William A. Carroll, Murali Gopalakrishnan, Eduardo Jose Vicente Molinari, Rachel A. Davis-Taber, Victoria Eleanor Sarah Scott
  • Tricyclic dihydropyrazolone and tricyclic dihydroisoxazolone potassium channel openers
    Publication number: 20030171394
    Abstract: Compounds of formula I 1
    Type: Application
    Filed: January 22, 2003
    Publication date: September 11, 2003
    Inventors: Irene Drizin, Robert J. Altenbach, William A. Carroll
  • 4-Imidazole derivatives of benzyl and restricted benzyl sulfonamides, sulfamides, ureas, carbamates, and amides and their use
    Publication number: 20030073850
    Abstract: Compounds of formula I 1
    Type: Application
    Filed: February 17, 2000
    Publication date: April 17, 2003
    Inventors: Robert J. Altenbach, Michael D. Meyer, James F. Kerwin, Albert Khilevich, Teodozyj Kolasa, Jeffrey Rohde, William A. Carroll, Xenia Searle, Fan Yang
  • Novel radioligands and their use for identifying potassium channel modulators
    Publication number: 20030065182
    Abstract: The present invention relates to novel radioligands and test methods using those radioligands in screening compounds.
    Type: Application
    Filed: July 30, 2002
    Publication date: April 3, 2003
    Inventors: Robert J. Altenbach, Gary A. Rotert, William A. Carroll, Murali Gopalakrishnan, Eduardo Jose Vicente Molinari, Rachel A. Davis-Taber, Victoria Eleanor Sarah Scott
  • Tricyclic dihydropyrazolone and tricyclic dihydroisoxazolone potassium channel openers
    Patent number: 6538004
    Abstract: Compounds of formula I are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.
    Type: Grant
    Filed: February 7, 2001
    Date of Patent: March 25, 2003
    Assignee: Abbott Laboratories
    Inventors: Irene Drizin, Robert J. Altenbach, William A. Carroll
  • Pyrano piperidino and thiopyrano compounds and methods of use
    Publication number: 20030055035
    Abstract: 1
    Type: Application
    Filed: May 3, 2000
    Publication date: March 20, 2003
    Inventors: Willilam A. Carroll, Konstantinos A. Agrios, Robert J. Altenbach, Irene Drizin, Michael E. Kort
  • Imidazoles and related compounds as &agr;1A agonists
    Patent number: 6503935
    Abstract: Compounds having formula I: are useful in treating diseases prevented by or ameliorated with &agr;1A agonists. Also disclosed are &agr;1A agonist compositions and a method of activating &agr;1 adrenoceptors in a mammal.
    Type: Grant
    Filed: July 29, 1999
    Date of Patent: January 7, 2003
    Assignee: Abbott Laboratories
    Inventors: Robert J. Altenbach, Michael D. Meyer, James F. Kerwin, Jr., Mark W. Holladay, Albert Khilevich, Teodozyj Kolasa, Jeffrey Rohde, William A. Carroll