Patents by Inventor Robert J. Arceci

Robert J. Arceci has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human binding molecule against CD1a
    Patent number: 7968092
    Abstract: The present invention provides human binding molecules that specifically bind to CD1a, nucleic acid molecules encoding the human binding molecules, compositions comprising the human binding molecules and methods of identifying or producing the human binding molecules. The human binding molecules can be used in the diagnosis, prevention and treatment of neoplastic disorders and diseases.
    Type: Grant
    Filed: March 23, 2006
    Date of Patent: June 28, 2011
    Assignees: Crucell Holland B.V., The Johns Hopkins University
    Inventors: Mark Throsby, Marja van Meijer, Wilfred T. V. Germeraad, Robert J. Arceci, Ada M. Kruisbeek
  • Antibodies for P-glycoprotein encoded by the mdr1 gene and uses thereof
    Patent number: 5369009
    Abstract: A novel antibody capable of binding to a 170,000 dalton P-glycoprotein encoded by the mdr1 gene, wherein said antibody binds to an external epitope on the protein and does not substantially increase the intracellular accumulaton or the cytoxicity of either Daunomycin or vinblastine in multidrug resistant cells is described. Methods of use of such antibodies are also described.
    Type: Grant
    Filed: April 17, 1992
    Date of Patent: November 29, 1994
    Assignee: Dana Farber Cancer Institute
    Inventors: Robert J. Arceci, James M. Croop